Search Results - "Jin, Xiong"

A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential by Gobin, Emily, Bagwell, Kayla, Wagner, John, Mysona, David, Sandirasegarane, Sharmila, Smith, Nathan, Bai, Shan, Sharma, Ashok, Schleifer, Robert, She, Jin-Xiong

“…By understanding Matrix Metalloprotease (MMP) dysregulation from a pan-cancer perspective, this study sheds light on the diagnostic potentials of MMPs across…”
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Current understanding on the roles of gut microbiota in fish disease and immunity by Xiong, Jin-Bo, Nie, Li, Chen, Jiong

“…Intensive aquaculture has increased the severity and frequency of fish diseases. Given the functional importance of gut microbiota in various facets of host…”
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Cancer stem cells and differentiation therapy by Jin, Xiong, Jin, Xun, Kim, Hyunggee

“…Cancer stem cells can generate tumors from only a small number of cells, whereas differentiated cancer cells cannot. The prominent feature of cancer stem cells…”
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Temporal development of the gut microbiome in early childhood from the TEDDY study by Stewart, Christopher J., Ajami, Nadim J., O’Brien, Jacqueline L., Hutchinson, Diane S., Smith, Daniel P., Wong, Matthew C., Ross, Matthew C., Lloyd, Richard E., Doddapaneni, HarshaVardhan, Metcalf, Ginger A., Muzny, Donna, Gibbs, Richard A., Vatanen, Tommi, Huttenhower, Curtis, Xavier, Ramnik J., Rewers, Marian, Hagopian, William, Toppari, Jorma, Ziegler, Anette-G., She, Jin-Xiong, Akolkar, Beena, Lernmark, Ake, Hyoty, Heikki, Vehik, Kendra, Krischer, Jeffrey P., Petrosino, Joseph F.

“…The development of the microbiome from infancy to childhood is dependent on a range of factors, with microbial–immune crosstalk during this time thought to be…”
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The human gut microbiome in early-onset type 1 diabetes from the TEDDY study by Vatanen, Tommi, Franzosa, Eric A., Schwager, Randall, Tripathi, Surya, Arthur, Timothy D., Vehik, Kendra, Lernmark, Åke, Hagopian, William A., Rewers, Marian J., She, Jin-Xiong, Toppari, Jorma, Ziegler, Anette-G., Akolkar, Beena, Krischer, Jeffrey P., Stewart, Christopher J., Ajami, Nadim J., Petrosino, Joseph F., Gevers, Dirk, Lähdesmäki, Harri, Vlamakis, Hera, Huttenhower, Curtis, Xavier, Ramnik J.

“…Type 1 diabetes (T1D) is an autoimmune disease that targets pancreatic islet beta cells and incorporates genetic and environmental factors 1 , including…”
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Prospective virome analyses in young children at increased genetic risk for type 1 diabetes by Vehik, Kendra, Lynch, Kristian F., Wong, Matthew C., Tian, Xiangjun, Ross, Matthew C., Gibbs, Richard A., Ajami, Nadim J., Petrosino, Joseph F., Rewers, Marian, Toppari, Jorma, Ziegler, Anette G., She, Jin-Xiong, Lernmark, Ake, Akolkar, Beena, Hagopian, William A., Schatz, Desmond A., Krischer, Jeffrey P., Hyöty, Heikki, Lloyd, Richard E.

“…Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insulin deficiency and type 1 diabetes (T1D) 1 – 4 . Certain…”
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Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration‐approved drugs by Lin, Hui‐Ping, Singla, Bhupesh, Ghoshal, Pushpankur, Faulkner, Jessica L, Cherian‐Shaw, Mary, O'Connor, Paul M, She, Jin‐Xiong, Belin de Chantemele, Eric J, Csányi, Gábor

“…Background and Purpose Macropinocytosis is involved in many pathologies, including cardiovascular disorders, cancer, allergic diseases, viral and bacterial…”
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Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children by Bonifacio, Ezio, Beyerlein, Andreas, Hippich, Markus, Winkler, Christiane, Vehik, Kendra, Weedon, Michael N, Laimighofer, Michael, Hattersley, Andrew T, Krumsiek, Jan, Frohnert, Brigitte I, Steck, Andrea K, Hagopian, William A, Krischer, Jeffrey P, Lernmark, Åke, Rewers, Marian J, She, Jin-Xiong, Toppari, Jorma, Akolkar, Beena, Oram, Richard A, Rich, Stephen S, Ziegler, Anette-G

“…Around 0.3% of newborns will develop autoimmunity to pancreatic beta cells in childhood and subsequently develop type 1 diabetes before adulthood. Primary…”
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TP53 gain-of-function mutation promotes inflammation in glioblastoma by Ham, Seok Won, Jeon, Hee-Young, Jin, Xiong, Kim, Eun-Jung, Kim, Jun-Kyum, Shin, Yong Jae, Lee, Yeri, Kim, Se Hoon, Lee, Seon Yong, Seo, Sunyoung, Park, Min Gi, Kim, Hye-Mi, Nam, Do-Hyun, Kim, Hyunggee

“…Glioblastoma (GBM), the most severe and common brain tumor in adults, is characterized by multiple somatic mutations and aberrant activation of inflammatory…”
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Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study by Krischer, Jeffrey P, Lynch, Kristian F, Lernmark, Åke, Hagopian, William A, Rewers, Marian J, She, Jin-Xiong, Toppari, Jorma, Ziegler, Anette-G, Akolkar, Beena

“…We tested the associations between genetic background and selected environmental exposures with respect to islet autoantibodies and type 1 diabetes. Infants…”
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A novel monoclonal antibody associated with glucoside kills gastric adenocarcinoma AGS cells based on glycosylation target by Xu, Heng, Dun, Boying, Liu, Beiyi, Mysona, David, She, Jin‐Xiong, Ma, Rong

“…Glycosylation results in the production of glycans which are required for certain proteins to function. These glycans are also present on cell surfaces where…”
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Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins by Purohit, Sharad, Li, Tiehai, Guan, Wanyi, Song, Xuezheng, Song, Jing, Tian, Yanna, Li, Lei, Sharma, Ashok, Dun, Boying, Mysona, David, Ghamande, Sharad, Rungruang, Bunja, Cummings, Richard D., Wang, Peng George, She, Jin-Xiong

“…Glycan-binding proteins (GBPs) play critical roles in diverse cellular functions such as cell adhesion, signal transduction and immune response. Studies of the…”
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Modified upper and lower triangular splitting iterative method for a class of block two-by-two linear systems by Xiong, Jin-Song

“…Based on two triangular splitting of the coefficient matrix, a modified upper and lower triangular (MULT) splitting iterative method is proposed in this paper…”
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Multiplex Glycan Bead Array (MGBA ) for High Throughput and High Content Analyses of Glycan-Binding Proteins Including Natural Anti-Glycan Antibodies by Purohit, Sharad, She, Jin-Xiong

“…We present here detailed protocols for the newly developed multiplex glycan bead array (MGBA) for the high throughput and high content analyses of various…”
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Case report: Precise NGS and combined bevacizumab promote durable response in ALK-positive lung adenocarcinoma with multiple-line ALK-TKI resistance by Xiong, Jin, Xia, Lei

“…Liquid biopsies including pleural fluid or plasma are commonly applied for patients with advanced non-small cell lung cancer (NSCLC) and pleural effusion (PE)…”
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Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis by Niu, Qian, Huang, Zhuo-Chun, Wu, Xiao-Juan, Jin, Ya-Xiong, An, Yun-Fei, Li, Ya-Mei, Xu, Huan, Yang, Bin, Wang, Lan-Lan

“…Follicular helper T (Tfh) cells are specialized in helping B lymphocytes, which play a central role in autoimmune diseases that have a major B cell component,…”
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RTN4B‐mediated suppression of Sirtuin 2 activity ameliorates β‐amyloid pathology and cognitive impairment in Alzheimer's disease mouse model by Wang, Yan, Yang, Jing‐Qi, Hong, Ting-Ting, Sun, Yuan‐Hong, Huang, Hai‐Li, Chen, Feng, Chen, Xiong‐Jin, Chen, Hui‐Yi, Dong, Shan‐Shan, Cui, Li‐Li, Yang, Tie‐Lin

“…Sirtuin 2 (SIRT2) is an NAD+ dependent deacetylase that is the most abundant sirtuin protein in the brain. Accumulating evidence revealed the role of SIRT2 in…”
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Novel Biocompatible Polysaccharide-Based Self-Healing Hydrogel by Wei, Zhao, Yang, Jian Hai, Liu, Zhen Qi, Xu, Feng, Zhou, Jin Xiong, Zrínyi, Miklós, Osada, Yoshihito, Chen, Yong Mei

“…A novel biocompatible polysaccharide‐based self‐healing hydrogel, CEC‐l‐OSA‐l‐ADH hydrogel (“l” means “linked‐by”), is developed by exploiting the dynamic…”
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The prognostic value of m6A-related LncRNAs in patients with HNSCC: bioinformatics analysis of TCGA database by Zhou, Liu-qing, Shen, Jin-xiong, Zhou, Jie-yu, Hu, Yao, Xiao, Hong-jun

“…N6-methyladenosine (m6A) modifications play an essential role in tumorigenesis. These modifications modulate RNAs, including mRNAs and lncRNAs. However, the…”
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ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages by Yin, Jinlong, Kim, Sung Soo, Choi, Eunji, Oh, Young Taek, Lin, Weiwei, Kim, Tae-Hoon, Sa, Jason K., Hong, Jun Hee, Park, Se Hwan, Kwon, Hyung Joon, Jin, Xiong, You, Yeonhee, Kim, Ji Hye, Kim, Hyunggee, Son, Jaekyoung, Lee, Jeongwu, Nam, Do-Hyun, Choi, Kui Son, Shi, Bingyang, Gwak, Ho-Shin, Yoo, Heon, Iavarone, Antonio, Kim, Jong Heon, Park, Jong Bae

“…The interplay between glioblastoma stem cells (GSCs) and tumor-associated macrophages (TAMs) promotes progression of glioblastoma multiforme (GBM). However,…”
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