Search Results - "Jin, Weilin"

The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness by Gao, Xingchun, Jin, Weilin

“…Highlights • miRNAs are epigenetic regulators of glioblastoma stemness. • Aberrant expression of miR-218 can be observed in malignant gliomas. • Roles of…”
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EAT1 promotes tapetal cell death by regulating aspartic proteases during male reproductive development in rice by Niu, Ningning, Liang, Wanqi, Yang, Xijia, Jin, Weilin, Wilson, Zoe A., Hu, Jianping, Zhang, Dabing

“…Programmed cell death is essential for the development of multicellular organisms, yet pathways of plant programmed cell death and its regulation remain…”
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MicroRNA-218 Inhibits Glioma Invasion, Migration, Proliferation, and Cancer Stem-like Cell Self-Renewal by Targeting the Polycomb Group Gene Bmi1 by Tu, Yanyang, Gao, Xingchun, Li, Gang, Fu, Hualin, Cui, Daxiang, Liu, Hui, Jin, Weilin, Zhang, Yongsheng

“…Malignant gliomas are the most common central nervous system tumors and the molecular mechanism driving their development and recurrence is still largely…”
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Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy by Gao, Xingchun, Mi, Yajing, Guo, Na, Xu, Hao, Xu, Lixian, Gou, Xingchun, Jin, Weilin

“…Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3 CD56 natural killer T cells, which can be easily expanded from peripheral…”
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The Emerging Role of Myeloid-Derived Suppressor Cells in the Glioma Immune Suppressive Microenvironment by Mi, Yajing, Guo, Na, Luan, Jing, Cheng, Jianghong, Hu, Zhifang, Jiang, Pengtao, Jin, Weilin, Gao, Xingchun

“…Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid progenitor and precursor cells at different stages of differentiation, which play…”
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Probiotics, prebiotics, and postbiotics in health and disease by Ji, Jing, Jin, Weilin, Liu, Shuang‐Jiang, Jiao, Zuoyi, Li, Xiangkai

“…The gut microbiota and its homeostasis play a crucial role in human health. However, for some diseases related to the gut microbiota, current traditional…”
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Therapeutic applications of PARP inhibitors in ovarian cancer by Xie, Hongyu, Wang, Wenjie, Xia, Bairong, Jin, Weilin, Lou, Ge

“…•PARPi are an effective therapeutic option for HR-deficient ovarian cancer patients.•Chemotherapy-induced nerve impairment can be alleviated by…”
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Antitumor Effect of Simvastatin in Combination With DNA Methyltransferase Inhibitor on Gastric Cancer via GSDME-Mediated Pyroptosis by Xia, Ying, Jin, Yong, Cui, Daxiang, Wu, Xia, Song, Cunfeng, Jin, Weilin, Huang, Hai

“…Gasdermin E (GSDME) is one of the executors of pyroptosis, a type of programmed lytic cell death, which can be triggered by caspase-3 activation upon…”
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Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development by Dai, Jinxiang, Bercury, Kathryn K, Jin, Weilin, Macklin, Wendy B

“…The oligodendrocyte transcription factor Olig1 is critical for both oligodendrocyte development and remyelination in mice. Nuclear to cytoplasmic translocation…”
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Targeting DNA Repair Response Promotes Immunotherapy in Ovarian Cancer: Rationale and Clinical Application by Xie, Hongyu, Wang, Wenjie, Qi, Wencai, Jin, Weilin, Xia, Bairong

“…Immune checkpoint inhibitors (ICI) have emerged as a powerful oncologic treatment modality for patients with different solid tumors. Unfortunately, the…”
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Cancer cachexia: Focus on cachexia factors and inter-organ communication by Wang, Yongfei, Dong, Zikai, An, Ziyi, Jin, Weilin

“…Cancer cachexia is a multi-organ syndrome and closely related to changes in signal communication between organs, which is mediated by cancer cachexia factors…”
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Hexokinase 2 (HK2), the tumor promoter in glioma, is downregulated by miR-218/Bmi1 pathway by Liu, Hui, Liu, Nan, Cheng, Yingduan, Jin, Weilin, Zhang, Pengxing, Wang, Xin, Yang, Hongwei, Xu, Xiaoshan, Wang, Zhen, Tu, Yanyang

“…In cancer, glycolysis driving enzymes and their regulating microRNAs are one of the key focus of oncology research lately. The glycolytic enzyme hexokinase 2…”
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Liver cirrhosis: molecular mechanisms and therapeutic interventions by Dong, Zihe, Wang, Yeying, Jin, Weilin

“…Liver cirrhosis is the end‐stage of chronic liver disease, characterized by inflammation, necrosis, advanced fibrosis, and regenerative nodule formation…”
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Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain by Zhang, Ming, Wang, Jian, Zhang, Kaixiang, Lu, Guozhen, Liu, Yuming, Ren, Keke, Wang, Wenting, Xin, Dazhuan, Xu, Lingli, Mao, Honghui, Xing, Junlin, Gao, Xingchun, Jin, Weilin, Berry, Kalen, Mikoshiba, Katsuhiko, Wu, Shengxi, Lu, Q. Richard, Zhao, Xianghui

“…Ten-eleven translocation (TET) proteins, the dioxygenase for DNA hydroxymethylation, are important players in nervous system development and diseases. However,…”
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Circulating MiR-16-5p and MiR-19b-3p as Two Novel Potential Biomarkers to Indicate Progression of Gastric Cancer by Zhang, Jingpu, Song, Yang, Zhang, Chunlei, Zhi, Xiao, Fu, Hualin, Ma, Yue, Chen, Yunsheng, Pan, Fei, Wang, Kan, Ni, Jian, Jin, Weilin, He, Xianli, Su, Haichuan, Cui, Daxiang

“…Gastric cancer (GC) is the second most common cancer in China and the second leading cause of cancer-related death in the world. Identifying circulating…”
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USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade by Yang, Zhaojuan, Xu, Guiqin, Wang, Boshi, Liu, Yun, Zhang, Li, Jing, Tiantian, Tang, Ming, Xu, Xiaoli, Jiao, Kun, Xiang, Lvzhu, Fu, Yujie, Tang, Daoqiang, Zhang, Xiaoren, Jin, Weilin, Zhuang, Guanglei, Zhao, Xiaojing, Liu, Yongzhong

“…Oncogenic activation of KRAS and its surrogates is essential for tumour cell proliferation and survival, as well as for the development of protumourigenic…”
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Au-siRNA@ aptamer nanocages as a high-efficiency drug and gene delivery system for targeted lung cancer therapy by Yang, Yuming, Han, Yu, Sun, Qiuyang, Cheng, Jin, Yue, Caixia, Liu, Yanlei, Song, Jie, Jin, Weilin, Ding, Xianting, de la Fuente, Jesús M, Ni, Jian, Wang, Xiaoqiang, Cui, Daxiang

“…Gene and chemical therapy has become one of the rising stars in the field of molecular medicine during the last two decades. However, there are still numerous…”
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Induction and Maturation of Hepatocyte-Like Cells In Vitro : Focus on Technological Advances and Challenges by Xie, Ye, Yao, Jia, Jin, Weilin, Ren, Longfei, Li, Xun

“…Limited by the poor proliferation and restricted sources of adult hepatocytes, there is an urgent need to find substitutes for proliferation and cultivation of…”
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KIAA1522 potentiates TNFα-NFκB signaling to antagonize platinum-based chemotherapy in lung adenocarcinoma by Wang, Boshi, Jing, Tiantian, Jin, Weilin, Chen, Jinnan, Wu, Chengsi, Wang, Mingrong, Liu, Yizhen

“…Abstract Background The platinum-based chemotherapy is the first-line regimen for the treatment of Non-small cell lung cancer (NSCLC). However, the therapeutic…”
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Essential role of ALKBH5-mediated RNA demethylation modification in bile acid-induced gastric intestinal metaplasia by Yue, Ben, Cui, Ran, Zheng, Ruizhe, Jin, Weilin, Song, Chenlong, Bao, Tianshang, Wang, Ming, Yu, Fengrong, Zhao, Enhao

“…Bile acid reflux and subsequent caudal-related homeobox 2 (CDX2) activation contribute to gastric intestinal metaplasia (IM), a precursor of gastric cancer;…”
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