Search Results - "Jin, Sun Hee"
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Kojic acid-induced IL-6 production in human keratinocytes plays a role in its anti-melanogenic activity in skin
Published in Journal of dermatological science (01-06-2012)“…Abstract Background Kojic acid is a fungal metabolite widely used in medicinal and cosmetic formulations as a skin-lightening agent based on its de-pigmenting…”
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2
Keratinocyte-derived IL-24 plays a role in the positive feedback regulation of epidermal inflammation in response to environmental and endogenous toxic stressors
Published in Toxicology and applied pharmacology (15-10-2014)“…Keratinocytes are the major cellular components of human epidermis and play a key role in the modulating cutaneous inflammation and toxic responses. In human…”
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3
A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells
Published in Archives of toxicology (01-07-2019)“…Avobenzone is the most commonly used ultraviolet (UV) A filter ingredient in sunscreen. To investigate the biological activity of avobenzone in normal human…”
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4
Diallyl Biphenyl-Type Neolignans Have a Pharmacophore of PPARα/γ Dual Modulators
Published in Biomolecules & therapeutics (01-09-2020)“…Adiponectin secretion-promoting compounds have therapeutic potentials in human metabolic diseases. Diallyl biphenyl-type neolignan compounds, magnolol,…”
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5
Keratinocyte-derived IL-36γ plays a role in hydroquinone-induced chemical leukoderma through inhibition of melanogenesis in human epidermal melanocytes
Published in Archives of toxicology (01-08-2019)“…Chemical leukoderma is an acquired type of vitiligo that can be initiated by various exogenous chemicals such as hydroquinone (HQ), rhododendrol (RD), or…”
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IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway
Published in Journal of investigative dermatology (01-02-2013)“…Skin diseases can be characterized by their predominant CD4-positive T-helper (Th) cell profiles. Chronic dermatological conditions often give rise to abnormal…”
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3,4,5-Trimethoxycinnamate thymol ester inhibits melanogenesis in normal human melanocytes and 3D human epidermal equivalents via the PGC-1α-independent PPARγ partial agonism
Published in Journal of dermatological science (01-04-2022)“…•TCTE, an anti-melanogenic agent, increased adiponectin production.•TCTE acted as a PPARγ partial agonist.•A PPARγ antagonist attenuated the effect of TCTE on…”
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8
Leptin regulates the pro-inflammatory response in human epidermal keratinocytes
Published in Archives of Dermatological Research (01-05-2018)“…The role of leptin in cutaneous wound healing process has been suggested in genetically obese mouse studies. However, the molecular and cellular effects of…”
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9
Carnosine and Retinol Synergistically Inhibit UVB-Induced PGE2 Synthesis in Human Keratinocytes through the Up-Regulation of Hyaluronan Synthase 2
Published in Biomolecules & therapeutics (01-09-2024)“…Skin aging results from complex interactions of intrinsic and extrinsic factors, leading to structural and biochemical changes such as wrinkles and dryness…”
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10
Imiquimod, a Toll-Like Receptor 7 Agonist, Inhibits Melanogenesis and Proliferation of Human Melanocytes
Published in Journal of investigative dermatology (01-01-2009)Get full text
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Diallyl Biphenyl-Type Neolignans Have a Pharmacophore of PPARα/γ Dual Modulators
Published in Biomolecules & therapeutics (01-09-2020)“…Adiponectin secretion-promoting compounds have therapeutic potentials in human metabolic diseases. Diallyl biphenyl-type neolignan compounds, magnolol,…”
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12
Activation of Toll-like Receptors 1, 2, 4, 5, and 7 on Human Melanocytes Modulate Pigmentation
Published in Annals of dermatology (01-11-2010)“…Human melanocytes are not simply pigment-producing cells. It may be part of the inflammatory response, during which the pigmentary system may produce more…”
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13
Human melanocytes express functional Toll-like receptor 4
Published in Experimental dermatology (01-05-2008)“…Background: Melanocytes are not simply pigment‐producing cells, but produce substances with a range of biological functions including antimicrobial defense…”
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14
The retinoic acid-induced up-regulation of insulin-like growth factor 1 and 2 is associated with prolidase-dependent collagen synthesis in UVA-irradiated human dermal equivalents
Published in Journal of dermatological science (01-04-2012)“…Abstract Background Ultraviolet (UV) A irradiation causes the degeneration of extracellular matrix in the skin dermis, mainly due to disrupted collagen…”
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15
Human melanocytes form a PAX3-expressing melanocyte cluster on Matrigel by the cell migration process
Published in Journal of dermatological science (01-10-2014)“…Graphical abstract…”
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16
Methyl-β-cyclodextrin, a specific cholesterol-binding agent, inhibits melanogenesis in human melanocytes through activation of ERK
Published in Archives of Dermatological Research (01-09-2008)“…Cholesterol has been suggested to regulate cell differentiation. In this study, we have examined the effects of cholesterol modulation on pigmentation of skin…”
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17
LPS induces melanogenesis through p38 MAPK activation in human melanocytes
Published in Archives of Dermatological Research (01-07-2008)Get full text
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18
Cell penetrable peptide nucleic acids targeting PDZK1IP1 with anti-inflammatory potential in human keratinocytes
Published in Bioorganic & medicinal chemistry letters (01-01-2025)“…[Display omitted] •A primary amine chain was introduced into the nucleobase to synthesize a modified PNA.•Chemical modification enhanced the water solubility…”
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Benzophenone-3 and benzophenone-8 exhibit obesogenic activity via peroxisome proliferator-activated receptor γ pathway
Published in Toxicology in vitro (01-09-2020)“…Benzophenone-3 (BP-3) and benzopenone-8 (BP-8) are commonly used ultraviolet (UV) filter ingredients in diverse sunscreen products. Recently, the obesogenic…”
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Sunscreen filter octocrylene is a potential obesogen by acting as a PPARγ partial agonist
Published in Toxicology letters (01-02-2022)“…[Display omitted] •Ultraviolet B filter octocrylene (OC) promoted adipogenesis in hBM-MSCs.•OC directly bound to PPARγ and recruited coactivator proteins,…”
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