Search Results - "Jin, Ningyi"
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Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model
Published in Cell research (01-02-2013)“…Dear Editor, The recent controversial studies of man-made avian flu viruses caused a media storm, and brought new con-cerns to the potential of an avian…”
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SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment
Published in Frontiers in microbiology (06-01-2022)“…Mitochondria, which is essential for adequate innate immune response, energy metabolism and mitochondria reactive oxygen species (ROS) production, might be in…”
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A Tentative Tamdy Orthonairovirus Related to Febrile Illness in Northwestern China
Published in Clinical infectious diseases (06-05-2020)“…Many novel tick-borne viruses have been discovered by deep-sequencing technology in recent years; however, their medical significance is unknown. We obtained…”
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Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury
Published in PLoS pathogens (16-03-2020)“…Infection with avian influenza A H5N1 virus results in acute lung injury (ALI) and has a high mortality rate (52.79%) because there are limited therapies…”
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A recombinant Lactobacillus plantarum strain expressing the spike protein of SARS-CoV-2
Published in International journal of biological macromolecules (01-10-2020)“…Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic in the past…”
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Mucosal IgA response elicited by intranasal immunization of Lactobacillus plantarum expressing surface-displayed RBD protein of SARS-CoV-2
Published in International journal of biological macromolecules (01-11-2021)“…Coronavirus Disease 2019 (COVID-19) caused by a novel betacoronavirus SARS-CoV-2 has been an ongoing global pandemic. Several vaccines have been developed to…”
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mRNA Vaccines Encoding the HA Protein of Influenza A H1N1 Virus Delivered by Cationic Lipid Nanoparticles Induce Protective Immune Responses in Mice
Published in Vaccines (Basel) (10-03-2020)“…The design of the mRNA vaccine involves the selection of in vitro transcription (IVT) systems and nonviral delivery vectors. This study aimed to verify the…”
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Retrospective surveillance of porcine circovirus 4 in pigs in Inner Mongolia, China, from 2016 to 2018
Published in Archives of virology (01-07-2021)“…A novel circovirus designated "porcine circovirus type 4" (PCV4) was recently reported in pigs with severe clinical disease in Hunan Province, China…”
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Origin, genetic diversity, adaptive evolution and transmission dynamics of Getah virus
Published in Transboundary and emerging diseases (01-07-2022)“…As a member of the Alphavirus, Getah virus (GETV) was becoming more serious and posing a serious threat to animal safety and public health. However, the…”
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Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma
Published in Frontiers in pharmacology (11-07-2022)“…Ferritinophagy is associated with tumor occurrence, development, and therapy effects. Ferritinophagy and ferroptosis are regulated by iron metabolism and are…”
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Inhibitors of endosomal acidification suppress SARS-CoV-2 replication and relieve viral pneumonia in hACE2 transgenic mice
Published in Virology journal (27-02-2021)“…Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2 and broke out as a global pandemic in late 2019. The acidic pH environment of endosomes is believed…”
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Sequence and phylogenetic analysis of novel porcine parvovirus 7 isolates from pigs in Guangxi, China
Published in PloS one (10-07-2019)“…Parvoviruses are a diverse group of viruses that infect a wide range of animals and humans. In recent years, advances in molecular techniques have resulted in…”
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Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants
Published in Nature communications (17-04-2023)“…A full understanding of the inactivated COVID-19 vaccine-mediated antibody responses to SARS-CoV-2 circulating variants will inform vaccine effectiveness and…”
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Trends and insights in dengue virus research globally: a bibliometric analysis (1995-2023)
Published in Journal of translational medicine (03-09-2024)“…Dengue virus (DENV) is the most widespread arbovirus. The World Health Organization (WHO) declared dengue one of the top 10 global health threats in 2019…”
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Genomic characteristics of an avipoxvirus 282E4 strain
Published in Virus research (15-10-2023)“…•For avipoxvirus 282E4 strain, the avipoxvirus 282E4 was shown to be divergent from known fowlpox virus isolates.•For the genome avipoxvirus 282E4, the linear…”
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FHL2 Inhibits SARS-CoV-2 Replication by Enhancing IFN-β Expression through Regulating IRF-3
Published in International journal of molecular sciences (26-12-2023)“…SARS-CoV-2 triggered the global COVID-19 pandemic, posing a severe threat to public health worldwide. The innate immune response in cells infected by…”
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Current Progress on Host Antiviral Factor IFITMs
Published in Frontiers in immunology (30-11-2020)“…Host antiviral factor interferon-induced transmembrane proteins (IFITMs) are a kind of small-molecule transmembrane proteins induced by interferon. Their…”
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Cryo-EM structure of severe fever with thrombocytopenia syndrome virus
Published in Nature communications (10-10-2023)“…The severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne human-infecting bunyavirus, which utilizes two envelope glycoproteins, Gn and Gc,…”
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Astragalus polysaccharides protects against acute leptospirosis by glycolysis-depended priming effect
Published in Biomedicine & pharmacotherapy (01-07-2022)“…Leptospirosis, caused by pathogenic leptospira, is a neglected infectious disease that causes acute kidney injury, bleeding disorders, and even death. People…”
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The associated killing of hepatoma cells using multilayer drug-loaded mats combined with fast neutron therapy
Published in Nano research (01-03-2021)“…Chemotherapeutic and radiation therapy have emerged as two most important treatment strategies to treat cancer in clinical practice; however, to improve…”
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