Search Results - "Jin, Lixia"

Urban shrinkage and growth: Measurement and determinants of economic resilience in the Pearl River Delta by Du, Zhiwei, Zhang, Hongou, Ye, Yuyao, Jin, Lixia, Xu, Qian

“…In the aftermath of the global financial crisis of 2008, China witnessed gradual shrinkage of cities in the Pearl River Delta (PRD). In this study, we…”
Get full text

Effect of hyaluronic acid on cytokines and immune cells change in patients of knee osteoarthritis by Jin, Lixia, Xu, Kangli, Liang, Yun, Du, Peng, Wan, Shengcheng, Jiang, Chang

“…Abstract Purpose To evaluate the changes of cytokines and immune cells after Intra-articular hyaluronic acid(IAHA)injections in patients with knee…”
Get full text

The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents by Canon, Jude, Osgood, Tao, Olson, Steven H, Saiki, Anne Y, Robertson, Rebecca, Yu, Dongyin, Eksterowicz, John, Ye, Qiuping, Jin, Lixia, Chen, Ada, Zhou, Jing, Cordover, David, Kaufman, Stephen, Kendall, Richard, Oliner, Jonathan D, Coxon, Angela, Radinsky, Robert

“…p53 is a critical tumor suppressor and is the most frequently inactivated gene in human cancer. Inhibition of the interaction of p53 with its negative…”
Get full text

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development by Sun, Daqing, Li, Zhihong, Rew, Yosup, Gribble, Michael, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chen, Xiaoqi, Chow, David, Deignan, Jeffrey, Duquette, Jason, Eksterowicz, John, Fisher, Benjamin, Fox, Brian M, Fu, Jiasheng, Gonzalez, Ana Z, Gonzalez-Lopez De Turiso, Felix, Houze, Jonathan B, Huang, Xin, Jiang, Min, Jin, Lixia, Kayser, Frank, Liu, Jiwen (Jim), Lo, Mei-Chu, Long, Alexander M, Lucas, Brian, McGee, Lawrence R, McIntosh, Joel, Mihalic, Jeff, Oliner, Jonathan D, Osgood, Tao, Peterson, Matthew L, Roveto, Philip, Saiki, Anne Y, Shaffer, Paul, Toteva, Maria, Wang, Yingcai, Wang, Yu Chung, Wortman, Sarah, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Yu, Ming, Zhao, Xiaoning, Zhou, Jing, Zhu, Jiang, Olson, Steven H, Medina, Julio C

“…We recently reported the discovery of AM-8553 (1), a potent and selective piperidinone inhibitor of the MDM2–p53 interaction. Continued research investigation…”
Get full text

High concentrations of single-walled carbon nanotubes lower soil enzyme activity and microbial biomass by Jin, Lixia, Son, Yowhan, Yoon, Tae Kyung, Kang, Yu Jin, Kim, Woong, Chung, Haegeun

“…Nanomaterials such as single-walled carbon nanotubes (SWCNTs) may enter the soil environment with unknown consequences resulting from the development of…”
Get full text

Enantiomeric separation of organophosphorus pesticides by high-performance liquid chromatography, gas chromatography and capillary electrophoresis and their applications to environmental fate and toxicity assays by Li, Ling, Zhou, Shanshan, Jin, Lixia, Zhang, Cheng, Liu, Weiping

“…In recent years, the continuous evolution of the field of stereochemistry has produced a heightened awareness of the applications of pure enantiomers of…”
Get full text

Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers by Seitz, Lisa, Jin, Lixia, Leleti, Manmohan, Ashok, Devika, Jeffrey, Jenna, Rieger, Aimee, Tiessen, Renger G., Arold, Gerhard, Tan, Joanne B. L., Powers, Jay P., Walters, Matthew J., Karakunnel, Joyson

“…Summary Adenosine suppresses antitumor immune responses via A 2a and A 2b receptors expressed on intratumoral immune cells. This effect is mediated by…”
Get full text

Photocatalytic research performance of zinc oxide/graphite phase carbon nitride catalyst and its application in environment by Liu, Haiyang, Wang, Zhe, Zhang, Heng, Jin, Lixia, Zhao, Yuehui

“…In this article, ZnO quantum dots (QDs)-g-C complexes were prepared by a combined sol–gel method and ultrasound-assisted chemical method, and ZnO-g-C…”
Get full text

China’s Urban Transformation in the Shadow of Regulatory Centralism: The Revitalization of Old Industrial Cities as a Case by Guo, Jie, Jin, Lixia, Yang, Yongchun

“…Recent research has focused on a dialectical examination of neoliberalism and China’s inherent authoritarian regulatory regime and the planned economy…”
Get full text

B cell subsets and dysfunction of regulatory B cells in IgG4-related diseases and primary Sjögren's syndrome: the similarities and differences by Lin, Wei, Jin, Lixia, Chen, Hua, Wu, Qingjun, Fei, Yunyun, Zheng, Wenjie, Wang, Qian, Li, Ping, Li, Yongzhe, Zhang, Wen, Zhao, Yan, Zeng, Xiaofeng, Zhang, Fengchun

“…IgG4-related disease (IgG4-RD) is a multisystem-involved autoimmune disease. Abnormally activated and differentiated B cells may play important roles…”
Get full text

IL-1β contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages by Jiang, Zengxin, Jin, Lixia, Jiang, Chang, Yan, Zuoqin, Cao, Yuanwu

“…Despite extensive research, there is still a need for safe and effective agents to promote spinal fusion. Interleukin (IL)-1β is an important factor which…”
Get full text

Polychlorinated biphenyls in surface sediments of Yueqing Bay, Xiangshan Bay, and Sanmen Bay in East China Sea by Yang, Huayun, Xue, Bin, Jin, Lixia, Zhou, Shanshan, Liu, Weiping

“…► Distribution and source of PCBs in sediments of Eastern China were analysed. ► Tri-PCB was identified as the prevalent contaminate of surface sediments. ►…”
Get full text

A Selective Prostaglandin E2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques by Fox, Brian M, Beck, Hilary P, Roveto, Philip M, Kayser, Frank, Cheng, Qingwen, Dou, Hannah, Williamson, Toni, Treanor, James, Liu, Hantao, Jin, Lixia, Xu, Guifen, Ma, Ji, Wang, Songli, Olson, Steven H

“…A high-throughput screen resulted in the discovery of benzoxazepine 1, an EP2 antagonist possessing low microsomal stability and potent CYP3A4 inhibition…”
Get full text

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction by Rew, Yosup, Sun, Daqing, Gonzalez-Lopez De Turiso, Felix, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Deignan, Jeffrey, Fox, Brian M, Gustin, Darin, Huang, Xin, Jiang, Min, Jiao, Xianyun, Jin, Lixia, Kayser, Frank, Kopecky, David J, Li, Yihong, Lo, Mei-Chu, Long, Alexander M, Michelsen, Klaus, Oliner, Jonathan D, Osgood, Tao, Ragains, Mark, Saiki, Anne Y, Schneider, Steve, Toteva, Maria, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H

“…Structure-based rational design led to the discovery of novel inhibitors of the MDM2–p53 protein–protein interaction. The affinity of these compounds for MDM2…”
Get full text

Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes by TCHAPARIAN, Eskouhie H, HOUGHTON, Jessica S, UYEDA, Craig, GRILLO, Mark P, LIXIA JIN

“…Sandwich-cultured rat hepatocytes are used in drug discovery for pharmacological and toxicological assessment of drug candidates, yet their utility as a…”
Get full text

Cage migration after unilateral instrumented transforaminal lumbar interbody fusion and associated risk factors: a modified measurement method by Jin, Lixia, Chen, Zixian, Jiang, Chun, Cao, Yuanwu, Feng, Zhenzhou, Jiang, Xiaoxing

“…Objective In this retrospective study, a modified measurement method was used to analyze cage migration during follow-up after unilateral instrumented…”
Get full text

A finite element analysis on comparing the stability of different posterior fixation methods for thoracic total en bloc spondylectomy by Liang, Yun, Cao, Yuanwu, Gong, Zhiguo, Jiang, Chang, Jin, Lixia, Li, Zheng, Chen, Zixian, Jiang, Chun, Jiang, Xiaoxing

“…To compare the spinal stability with different fixation methods after thoracic TES using finite element analysis METHODS: The spinal finite element model was…”
Get full text

Decreased programmed cell death ligand 2-positive monocytic myeloid-derived suppressor cells and programmed cell death protein 1-positive T-regulatory cells in patients with type 2 diabetes: implications for immunopathogenesis by Liu, Zhaoxiang, Zhang, Mingqiang, Shi, Xiaohu, Zhao, Wenhui, Cao, Chenxiang, Jin, Lixia, Wang, Yanlei, Xiao, Jianzhong

“…Objectives The activation of immune cells plays a significant role in the progression of type 2 diabetes. This study aimed to investigate the potential role of…”
Get full text

Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques by Hazuda, Daria J., Young, Steven D., Guare, James P., Anthony, Neville J., Gomez, Robert P., Wai, John S., Vacca, Joseph P., Handt, Larry, Motzel, Sherri L., Klein, Hilton J., Dornadula, Geethanjali, Danovich, Robert M., Witmer, Marc V., Keith A. A. Wilson, Tussey, Lynda, Schleif, William A., Gabryelski, Lori S., Jin, Lixia, Miller, Michael D., Casimiro, Danilo R., Emini, Emilio A., Shiver, John W.

“…We describe the efficacy of L-870812, an inhibitor of HIV-1 and SIV integrase, in rhesus macaques infected with the simian-human immunodeficiency virus (SHIV)…”
Get full text

Genetics of Metabolic Variations between Yersinia pestis Biovars and the Proposal of a New Biovar, microtus by Zhou, Dongsheng, Tong, Zongzhong, Song, Yajun, Han, Yanping, Pei, Decui, Pang, Xin, Zhai, Junhui, Li, Min, Cui, Baizhong, Qi, Zhizhen, Jin, Lixia, Dai, Ruixia, Du, Zongmin, Wang, Jin, Guo, Zhaobiao, Wang, Jian, Huang, Peitang, Yang, Ruifu

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text