Search Results - "Jin, Linhua"

TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment by Tabe, Yoko, Shi, Yue Xi, Zeng, Zhihong, Jin, Linhua, Shikami, Masato, Hatanaka, Yasuhito, Miida, Takashi, Hsu, Frank J, Andreeff, Michael, Konopleva, Marina

“…Hypoxia and interactions with bone marrow (BM) stromal cells have emerged as essential components of the leukemic BM microenvironment in promoting leukemia…”
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Growth kinetics of Cu surface layers in H2O2-BTA aqueous solutions by Kondoh, Eiichi, Toyama, Mao, Jin, Linhua, Hamada, Satomi, Shima, Shohei, Hiyama, Hirokuni

“…Slurries for the chemical mechanical polishing of Cu contain both an oxidizer and a corrosion inhibitor, in addition to abrasives. To understand the chemistry…”
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CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells by Jin, Linhua, Tabe, Yoko, Konoplev, Sergej, Xu, Yuanyuan, Leysath, Clinton E, Lu, Hongbo, Kimura, Shinya, Ohsaka, Akimichi, Rios, Mary-Beth, Calvert, Leslie, Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina

“…Chronic myelogenous leukemia (CML) is driven by constitutively activated Bcr-Abl tyrosine kinase, which causes the defective adhesion of CML cells to bone…”
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Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells by TABE, Yoko, LINHUA JIN, KONOPLEVA, Marina, TSUTSUMI-ISHII, Yuko, YUANYUAN XU, MCQUEEN, Teresa, PRIEBE, Waldemar, MILLS, Gordon B, OHSAKA, Akimichi, NAGAOKA, Isao, ANDREEFF, Michael

“…Integrin-linked kinase (ILK) directly interacts with beta integrins and phosphorylates Akt in a phosphatidylinositol 3-kinase (PI3K)-dependent manner. In this…”
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MDM2 Antagonist Nutlin-3 Displays Antiproliferative and Proapoptotic Activity in Mantle Cell Lymphoma by Tabe, Yoko, Sebasigari, Denise, Jin, Linhua, Rudelius, Martina, Davies-Hill, Theresa, Miyake, Kazunori, Miida, Takashi, Pittaluga, Stefania, Raffeld, Mark

“…Purpose: Mantle cell lymphoma (MCL) has one of the poorest prognoses of the non-Hodgkin's lymphomas, and novel therapeutic approaches are needed. We wished to…”
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Cell-Adhesive Matrices Composed of RGD Peptide-Displaying M13 Bacteriophage/Poly(lactic-co-glycolic acid) Nanofibers Beneficial to Myoblast Differentiation by Shin, Yong Cheol, Lee, Jong Ho, Jin, Linhua, Kim, Min Jeong, Kim, Chuntae, Hong, Suck Won, Oh, Jin Woo, Han, Dong-Wook

“…Recently, there has been considerable effort to develop suitable scaffolds for tissue engineering applications. Cell adhesion is a prerequisite for cells to…”
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Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment by Jin, Linhua, Tabe, Yoko, Lu, Hongbo, Borthakur, Gautam, Miida, Takashi, Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina

“…Abstract We investigated the antileukemia effects and molecular mechanisms of apoptosis induction by simultaneous blockade of PI3K and mutant FLT3 in AML cells…”
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MDM2 antagonist Nutlin-3 enhances bortezomib-mediated mitochondrial apoptosis in TP53-mutated mantle cell lymphoma by Jin, Linhua, Tabe, Yoko, Kojima, Kensuke, Zhou, Yixin, Pittaluga, Stefania, Konopleva, Marina, Miida, Takashi, Raffeld, Mark

“…Abstract This study demonstrated a pronounced synergistic growth-inhibitory effect of an MDM2 inhibitor Nutlin-3 and a proteasome inhibitor bortezomib in…”
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TGF‐β receptor kinase inhibitor LY2109761 reverses the anti‐apoptotic effects of TGF‐β1 in myelo‐monocytic leukaemic cells co‐cultured with stromal cells by Xu, Yuanyuan, Tabe, Yoko, Jin, Linhua, Watt, Julie, McQueen, Teresa, Ohsaka, Akimichi, Andreeff, Michael, Konopleva, Marina

“…Summary Transforming growth factor β1 (TGF‐β1) is an essential regulator of cell proliferation, survival and apoptosis, depending on the cellular context…”
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PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment by Jin, Linhua, Tabe, Yoko, Kojima, Kensuke, Shikami, Masato, Benito, Juliana, Ruvolo, Vivian, Wang, Rui-Yu, McQueen, Teresa, Ciurea, Stefan O., Miida, Takashi, Andreeff, Michael, Konopleva, Marina

“…Both phosphatidylinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin signaling and antiapoptotic Bcl-2 family members are critical for survival of…”
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Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells by Tabe, Yoko, Konopleva, Marina, Contractor, Rooha, Munsell, Mark, Schober, Wendy D., Jin, Linhua, Tsutsumi-Ishii, Yuko, Nagaoka, Isao, Igari, Jun, Andreeff, Michael

“…The multidrug resistance 1 (MDR1) gene product P-glycoprotein (P-gp) is frequently implicated in cross-resistance of tumors to chemotherapeutic drugs. In…”
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Molecular Mechanisms Of Inhibition Of Ribosomal Biogenesis and Translational Flux By The Selective Inhibitor Of Nuclear Export (SINE) XPO1/CRM1 Antagonist KPT-185 In Mantle Cell Lymphoma by Tabe, Yoko, Kojima, Kensuke, Jin, Linhua, Iwanami, Hiroko, Matsushita, Hiromichi, Kazuno, Saiko, Fujimura, Tsutomu, Ueno, Takashi, Miida, Takashi, Andreeff, Michael

“…Exportin 1 (XPO1/CRM1) mediates transport of a number of cargo molecules including transcription factors and ribosomal subunits from the nucleus to cytoplasm…”
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Stimulated myogenic differentiation of C2C12 murine myoblasts by using graphene oxide by Kim, Min Jeong, Lee, Jong Ho, Shin, Yong Cheol, Jin, Linhua, Hong, Suck Won, Han, Dong-Wook, Kim, Yong-Joo, Kim, Bongju

“…Currently, applications of graphene and its derivatives have been reported in many fields. In particular, graphene oxide (GO) has been studied for biomedical…”
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Cell-adhesive RGD peptide-displaying M13 bacteriophage/PLGA nanofiber matrices for growth of fibroblasts by Shin, Yong Cheol, Lee, Jong Ho, Jin, Linhua, Kim, Min Jeong, Oh, Jin-Woo, Kim, Tai Wan, Han, Dong-Wook

“…M13 bacteriophages can be readily fabricated as nanofibers due to non-toxic bacterial virus with a nanofiber-like shape. In the present study, we prepared…”
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Stimulated myoblast differentiation on graphene oxide-impregnated PLGA-collagen hybrid fibre matrices by Shin, Yong Cheol, Lee, Jong Ho, Jin, Linhua, Kim, Min Jeong, Kim, Yong-Joo, Hyun, Jung Keun, Jung, Tae-Gon, Hong, Suck Won, Han, Dong-Wook

“…Electrospinning is a simple and effective method for fabricating micro- and nanofiber matrices. Electrospun fibre matrices have numerous advantages for use as…”
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Crystal structure of 4-methoxy- N -phenylbenzamide by Wang, Zhijun, Lei, Haiying, Jin, Linhua, Zhu, Ruitao

“…In the title molecule, C 14 H 13 NO 2 , the dihedral angle between the planes of the benzene rings is 65.18 (4)°. The central amide group has about the same…”
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Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion by Chen, Fei, El-Naccache, Darine W., Ponessa, John J., Lemenze, Alexander, Espinosa, Vanessa, Wu, Wenhui, Lothstein, Katherine, Jin, Linhua, Antao, Olivia, Weinstein, Jason S., Damani-Yokota, Payal, Khanna, Kamal, Murray, Peter J., Rivera, Amariliz, Siracusa, Mark C., Gause, William C.

“…Macrophages are known to mediate anti-helminth responses, but it remains uncertain which subsets are involved or how macrophages actually kill helminths. Here,…”
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The anti-tumoral effect of PI3K inhibitor and MEK inhibitor combined with STI571 on chronic myeloid leukemia cells in a bone marrow stromal cell co-culture system by Jin, Linhua, Kato, Atsushi, Tabe, Yoko

“…The goal of this study was to elucidate the functional roles of PI3K/AKT and MEK/ERK signaling on the proliferation and apoptosis of STI571-sensitive and…”
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Growth kinetics of Cu surface layers in H 2 O 2 –BTA aqueous solutions by Kondoh, Eiichi, Toyama, Mao, Jin, Linhua, Hamada, Satomi, Shima, Shohei, Hiyama, Hirokuni

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Structures of Cu surfaces developing in benzotriazole solutions: Effect of pH by Kondoh, Eiichi, Kawakami, Tatsuya, Watanabe, Mitsuhiro, Jin, Linhua, Hamada, Satomi, Shima, Shohei, Hiyama, Hirokuni

“…The effect of pH on layer formation onto clean Cu surfaces in benzotriazole (BTA) aqueous solutions was studied by in situ spectroscopic ellipsometry. The…”
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