Search Results - "Jin, Jide"

Overexpression of Hepatocyte Growth Factor in Dental Pulp Stem Cells Ameliorates the Severity of Psoriasis by Reducing Inflammatory Responses by Meng, Hongfang, Wei, Fen, Zhou, Ying, Hu, Lei, Ge, Zhiqiang, Jin, Jide, Wang, Hua, Wu, Chu-Tse

“…Psoriasis is an autoimmune disease still lacking standard treatment, and it has been demonstrated that mesenchymal stem cells (MSCs) are capable of…”
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Recombinant neorudin and its active metabolite hirudin: the fate in vivo of a novel anticoagulant drug by Li, Qiang, Liu, Yubin, Ren, Boyuan, Jin, Jiayan, Zhang, Lin, Wu, ChuTse, Jin, JiDe

“…Thrombosis, a prevalent condition, can provoke severe health issues like acute coronary syndrome (ACS), deep vein thrombosis (DVT), and pulmonary embolism…”
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A phase I, single and continuous dose administration study on the safety, tolerability, and pharmacokinetics of neorudin, a novel recombinant anticoagulant protein, in healthy subjects by Liu, Yubin, Wang, Meixia, Dong, Xiaona, He, Jia, Zhang, Lin, Zhou, Ying, Xia, Xia, Dou, Guifang, Wu, Chu‐tse, Jin, Jide

“…The aim of this study was to evaluate the tolerability, safety, and pharmacokinetics of single and continuous dose administration of recombinant neorudin…”
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K-ras Mutations in Lung Tumors from NNK-treated Mice with Lipopolysaccharide-elicited Lung Inflammation by KEOHAVONG, Phouthone, KAHKONEN, Beth, KINCHINGTON, Edwina, JINLING YIN, JIDE JIN, XIAOPING LIU, SIEGFRIED, Jill M, PETER DI, Y

“…Chronic lung inflammation has been associated with an increased risk of lung cancer. However, it is unclear whether such an event affects the incidence of…”
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Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis by Stabile, Laura P, Rothstein, Mary E, Keohavong, Phouthone, Jin, Jide, Yin, Jinling, Land, Stephanie R, Dacic, Sanja, Luong, The Minh, Kim, K Jin, Dulak, Austin M, Siegfried, Jill M

“…The hepatocyte growth factor (HGF)/c-Met signaling pathway is involved in lung tumor growth and progression, and agents that target this pathway have clinical…”
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Aberrant Gene Promoter Methylation in Sputum from Individuals Exposed to Smoky Coal Emissions by YANG LIU, QING LAN, MIN SHEN, JIDE JIN, MUMFORD, Judy, DIANXU REN, KEOHAVONGI, Phouthone

“…Background: Recent studies suggested the potential for aberrant gene promoter methylation in sputum as a predictive marker for lung cancer. Here, the promoter…”
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Development, validation, and clinical pharmacokinetic application of ultra-performance liquid chromatography/tandem mass spectrometry method for simultaneously determining a novel recombinant hirudin derivative (Neorudin) and its active metabolite in human serum by Dong, Xiaona, Meng, Zhiyun, Jin, Jide, Gu, Ruolan, Dou, Guifang

“…•A UPLC–MS/MS assay was used to evaluate EH and HV2 in human serum samples.•The method was robust and optimized for relevant conditions.•EH and HV2 were stable…”
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Predicting the metabolic characteristics of neorudin, a novel anticoagulant fusion protein, in patients with deep vein thrombosis by Dong, Xiaona, Meng, Zhiyun, Gu, Ruolan, Zhu, Xiaoxia, Gan, Hui, Jin, Jide, Liu, Jianglin, Dou, Guifang

“…Recombinant neorudin (EPR-hirudin, EH) is an inactive prodrug that is converted to its active metabolite, hirudin variant 2-Lys47 (HV2), at the thrombus site…”
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Evaluating prodrug characteristics of a novel anticoagulant fusion protein neorudin, a prodrug targeting release of hirudin variant 2-Lys47 at the thrombosis site, by means of in vitro pharmacokinetics by Dong, Xiaona, Gu, Ruolan, Zhu, Xiaoxia, Gan, Hui, Liu, Jianglin, Jin, Jide, Meng, Zhiyun, Dou, Guifang

“…Recombinant neorudin (EPR-hirudin, EH), a low-bleeding anticoagulant fusion protein, is an inactive prodrug designed to be converted to the active metabolite,…”
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Recent advances in the therapeutic efficacy of hepatocyte growth factor gene‐modified mesenchymal stem cells in multiple disease settings by Meng, Hong‐fang, Jin, Jide, Wang, Hua, Wang, Li‐sheng, Wu, Chu‐tse

“…Mesenchymal stem cell (MSC) therapy is considered a new treatment for a wide range of diseases and injuries, but challenges remain, such as poor survival,…”
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Long-term hypoxia inhibits the passage-dependent stemness decrease and senescence increase of human dental pulp stem cells by Meng, Hongfang, Wei, Fen, Ge, Zhiqiang, Jin, Jide, Wang, Hua, Wang, Li-sheng, Wu, Chu-tse

“…Dental pulp stem cells (DPSCs) derived from discarded orthodontic teeth are easily obtained and have become a promising source for mesenchymal stem cell-based…”
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KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients by Gao, Weimin, Jin, Jide, Yin, Jinling, Land, Stephanie, Gaither‐Davis, Autumn, Christie, Neil, Luketich, James D., Siegfried, Jill M., Keohavong, Phouthone

“…Mutations in the KRAS and TP53 genes have been found frequently in lung tumors and specimens from individuals at high risk for lung cancer and have been…”
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Spectral and Energy Efficiency of Downlink MU-MIMO Systems with MRT by Weiqiang Tan Shi Jin Jide Yuan

“…This paper studies the achievable spectral efficiency （SE） of downlink multiuser multiple-input-multiple-output （MIMO） system, where the base station （BS） is…”
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Abstract 4377: Pulmonary inflammation and lung tumorigenesis in mice by Keohavong, Phouthone, Kahkonen, Beth, Kinchington, Edwina, Yin, Jinling, Jin, Jide, Siegfried, Jill M., Di, Peter

“…Abstract Chronic inflammation has been suggested to be associated with an increased risk of human cancer, including lung cancer, the leading cause of cancer…”
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High mobility group box 1 protein inhibits the proliferation of human mesenchymal stem cells and promotes their migration and differentiation along osteoblastic pathway by Meng, Erhong, Guo, Zikuan, Wang, Hengxiang, Jin, Jide, Wang, Jinsong, Wang, Hua, Wu, Cutse, Wang, Lisheng

“…Extracellular high mobility group box 1 (HMGB1) is a novel cytokine that takes part in the processes of inflammation, tissue damage and regeneration…”
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Locally activity-released bifunctional fusion protein enhances antithrombosis and alleviates bleeding risk by Shi, Bingxing, Yu, Aiping, Liu, Yuying, Li, Jingchuan, Jin, Jide, Dong, Chunna, Wu, Chutse

“…Despite the fact that lytic therapy of thromboembolic disorder has been achieved, reocclusion of the damaged vessels and bleeding complication frequently…”
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Precipitation Behaviors in the Diffusion Affected Zone of TLP Bonded Single Crystal Superalloy Joint by Sheng, Naicheng, Liu, Jide, Jin, Tao, Sun, Xiaofeng, Hu, Zhuangqi

“…The single crystal superalloys were joined by transient liquid phase(TLP) bonding. The precipitating behavior in the diffusion affected zone(DAZ) was studied…”
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High Temperature Stress Rupture Anisotropy of a Ni-Based Single Crystal Superalloy by Wang, Guanglei, Liu, Jinlai, Liu, Jide, Jin, Tao, Sun, Xiaofeng, Sun, Xudong, Hu, Zhuangqi

“…High temperature stress rupture anisotropies of a second generation Ni-base single crystal（SC） superalloy specimens with [001], [011] and [111] orientations…”
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Influence of the Substrate Orientation on the Isothermal Solidification during TLP Bonding Single Crystal Superalloys by Sheng, Naicheng, Li, Bo, Liu, Jide, Jin, Tao, Sun, Xiaofeng, Hu, Zhuangqi

“…Angle deviations between the two substrates during transient liquid phase （TLP） bonding single crystal superalloys cannot be avoided. In the present work,…”
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