Search Results - "Jin, Jiangli"
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A phase I, randomized study to evaluate the safety, tolerability, and pharmacokinetics of mefunidone in healthy subjects
Published in Frontiers in pharmacology (12-06-2024)“…Mefunidone is a novel synthetic compound and is better when compared to pirfenidone for the anti-fibrotic treatment of renal fibrosis in end-stage renal…”
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Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease
Published in Acta neuropathologica communications (21-05-2021)“…Abstract Cerebral amyloid angiopathy (CAA) contributes to accelerated cognitive decline in Alzheimer’s disease (AD) dementia and is a common finding at…”
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1031 Association Between Objective Sleep Architecture and Biomarkers of Alzheimer's Disease
Published in Sleep (New York, N.Y.) (20-04-2024)“…Abstract Introduction Growing evidence suggests a bi-directional association between sleep and Alzheimer’s disease (AD), with several studies showing an…”
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Safety, pharmacokinetics, and pharmacodynamics of TG103, a novel long-acting GLP-1/Fc fusion protein after a single ascending dose in Chinese healthy subjects
Published in European journal of pharmaceutical sciences (01-06-2023)“…TG103 is a novel GLP-1/Fc fusion protein, developed for the treatment of type 2 diabetes and obesity. This trial was designed to assess the safety and…”
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Acarbose, the α-glucosidase inhibitor, attenuates the blood pressure and splanchnic blood flow responses to meal in elderly patients with postprandial hypotension concomitant with abnormal glucose metabolism
Published in Blood pressure monitoring (01-02-2016)“…Postprandial hypotension (PPH) is a unique clinical phenomenon in the elderly, but its underlying pathogenesis has not been completely elucidated, and drug…”
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DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque
Published in Clinical epigenetics (01-12-2021)“…Abstract Background Atherosclerotic plaque vulnerability is a key feature of atheroprogression and precipitating acute cardiovascular events. Although the…”
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Transcript levels in plasma contribute substantial predictive value as potential Alzheimer's disease biomarkers in African Americans
Published in EBioMedicine (01-04-2022)“…African Americans (AA) remain underrepresented in Alzheimer's disease (AD) research, despite the prevalence of AD being double in AA compared to non-Hispanic…”
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DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A 2 in human vulnerable atherosclerotic plaque
Published in Clinical epigenetics (21-08-2021)“…Atherosclerotic plaque vulnerability is a key feature of atheroprogression and precipitating acute cardiovascular events. Although the pivotal role of…”
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A ɑ-KA fluorescent probe for discrimination of blood cancer serum
Published in 中国化学快报:英文版 (2017)“…a-Ketoglutaric acid(a-KA) is an important metabolic intermediate in tricarboxylic acid circle in our body.The mutations of isocitrate dehydrogenase-1(IDH1) and…”
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