Search Results - "Jin, Chun Mei"
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1
Synthesis and Antimicrobial Activity Evaluation of Imidazole‐Fused Imidazo[2,1‐b][1,3,4]thiadiazole Analogues
Published in ChemMedChem (05-08-2021)“…Three series of new imidazole‐fused imidazo[2,1‐b][1,3,4]thiadiazole analogues (compounds 20 a–g, 21 a–g, and 22 a–g) have been synthesized, and their…”
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2
Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents
Published in Molecules (Basel, Switzerland) (29-02-2016)“…New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and…”
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3
Synthesis and evaluation of in vitro and in vivo anti-Toxoplasma gondii activity of tetraoxane-substituted ursolic acid derivatives
Published in Natural product research (02-11-2023)“…A series of derivatives of ursolic acid (UA) were synthesised, the anti-Toxoplasma gondii activity was tested, and the selectivity index (SI) of these…”
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4
Synthesis and Pharmacological Evaluation of New 3,4-Dihydroisoquinolin Derivatives Containing Heterocycle as Potential Anticonvulsant Agents
Published in Molecules (Basel, Switzerland) (29-11-2016)“…Two novel series of 3,4-dihydroisoquinolin with heterocycle derivatives ( - and - ) were synthesized and evaluated for their anticonvulsant activity using…”
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5
Synthesis and evaluation of mycophenolic acid derivatives as potential anti-Toxoplasma gondii agents
Published in Medicinal chemistry research (01-12-2021)“…Nineteen mycophenolic acid (MPA) derivatives were designed and synthesized, and their anti- Toxoplasma activity evaluated for the first time. Among them, N…”
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6
Evaluation of the anti-Toxoplasma gondii Activity of Hederagenin in vitro and in vivo
Published in Korean journal of parasitology (01-06-2021)“…Toxoplasma gondii infection is widespread worldwide, not only posing a serious threat to human food safety and animal husbandry, but also endangering human…”
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7
Anti-toxoplasmosis Effects of Oleuropein Isolated from Fraxinus rhychophylla
Published in Biological & Pharmaceutical Bulletin (01-12-2008)“…Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii, with very few therapeutic treatment options. Typically, the choices for treatment are…”
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8
Synthesis and biological evaluation of ursolic acid derivatives bearing triazole moieties as potential anti-Toxoplasma gondii agents
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…Ursolic acid (UA), a plant-derived compound, has many properties beneficial to health. In the present study, we synthesised three series of novel UA…”
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9
The Methanol Extract of Azadirachta indica A. Juss Leaf Protects Mice Against Lethal Endotoxemia and Sepsis
Published in Biomolecules & therapeutics (2012)“…In the present study, the inhibitory effect of neem leaf extract (NLE) on lipopolysaccaride (LPS)-induced nitric oxide (NO) and tumor necrosis factor-α (TNF-α)…”
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10
Effects of anonaine on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells
Published in Molecules (Basel, Switzerland) (27-02-2008)“…The effects of anonaine, an aporphine isoquinoline alkaloid, on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells were investigated. Anonaine…”
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11
Liriodenine inhibits dopamine biosynthesis and L-DOPA-induced dopamine content in PC12 cells
Published in Archives of pharmacal research (01-08-2007)“…The inhibitory effects of liriodenine, an aporphine isoquinoline alkaloid, on dopamine biosynthesis and L-DOPA-induced dopamine content increases in PC12 cells…”
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12
Effects of (1R,9S)-β-Hydrastine on Intracellular Calcium Concentration in PC12 Cells
Published in Biological & pharmaceutical bulletin (01-08-2007)“…(1R,9S)-β-Hydrastine (BHS) decreases the basal intracellular Ca2+ concentration ([Ca2+]i) in PC12 cells.5) This study examined the effects of (1R,9S)-BHS on…”
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13
Evaluation of the anti-Toxoplasma gondii Activity of Hederagenin in vitro and in vivo
Published in Korean journal of parasitology (2021)“…Toxoplasma gondii infection is widespread worldwide, not only posing a serious threat to human food safety and animal husbandry, but also endangering human…”
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14
Inhibitory effects of (1R,9S)-beta-Hydrastine on calcium transport in PC12 cells
Published in Archives of pharmacal research (01-01-2007)“…(1R,9S)-beta-Hydrastine (BHS), at 100 microM, has been shown to mainly reduce the K+-induced dopamine release and Ca2+ influx by blocking the L-type Ca2+…”
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15
The Methanol Extract of Azadirachta indica A. Juss Leaf Protects Mice Against Lethal Endotoxemia and Sepsis
Published in Biomolecules & therapeutics (31-01-2012)“…In the present study, the inhibitory effect of neem leaf extract (NLE) on lipopolysaccaride (LPS)-induced nitric oxide (NO) and tumor necrosis factor-α (TNF-α)…”
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16
Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells
Published in European journal of pharmacology (10-06-2008)“…The effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells were investigated. Harman and norharman at a…”
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17
Induction of dopamine biosynthesis by l-DOPA in PC12 cells: Implications of l-DOPA influx and cyclic AMP
Published in European journal of pharmacology (04-09-2008)“…The effects of 3,4-dihydroxyphenylalanine ( l-DOPA) on dopamine biosynthesis and cytotoxicity were investigated in PC12 cells. l-DOPA treatment (20–200 μM)…”
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18
Liriodenine Inhibits Dopamine Biosynthesis and L-DOPA-Induced Dopamine Content in PC12 Cells
Published in Archives of pharmacal research (2007)“…The inhibitory effects of liriodenine, an aporphine isoquinoline alkaloid, on dopamine biosynthesis and L-DOPA-induced dopamine content increases in PC12 cells…”
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19
Inhibitory Effects of $(1R,9S)-{\beta}-Hydrastine$ on Calcium Transport in PC12 Cells
Published in Archives of pharmacal research (2007)“…[ $(1R,9S)-{\beta} ]-Hydrastine$ (BHS), at $100{\mu}M$, has been shown to mainly reduce the $K^+-induced$ dopamine release and $Ca^{2+}$ influx by blocking the…”
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20
Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents
Published in European journal of medicinal chemistry (05-10-2018)“…Four new series of arctigenin derivatives were designed, synthesised, and evaluated for their anti-Toxoplasma gondii activity in vitro and in vivo. Among the…”
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