Search Results - "Jimeno, Sonia"
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LipoBots: Using Liposomal Vesicles as Protective Shell of Urease‐Based Nanomotors
Published in Advanced functional materials (01-10-2020)“…Developing self‐powered nanomotors made of biocompatible and functional components is of paramount importance in future biomedical applications. Herein, the…”
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Ferrofluid based on polyethylene glycol-coated iron oxide nanoparticles: Characterization and properties
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (05-03-2013)“…[Display omitted] ► Ferrofluid formed by adsorption of unmodified polyethylene glycol. ► Effect of size and concentration of polyethylene glycol on properties…”
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EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks
Published in Nature communications (13-05-2019)“…The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is necessary for the repair of DNA…”
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The role of RNA and RNA-related proteins in the regulation of DNA double strand break repair pathway choice
Published in DNA repair (01-09-2019)“…DNA end resection is a critical step in the repair of DNA double strand breaks. It controls the way the lesion is going to be repaired, thus its regulation has…”
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ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
Published in Nature communications (17-09-2021)“…The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA lesions. RNA editing, the…”
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The Effect of Atypical Nucleic Acids Structures in DNA Double Strand Break Repair: A Tale of R-loops and G-Quadruplexes
Published in Frontiers in genetics (08-10-2021)“…The fine tuning of the DNA double strand break repair pathway choice relies on different regulatory layers that respond to environmental and local cues. Among…”
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Histone H3K56 acetylation, Rad52, and non-DNA repair factors control double-strand break repair choice with the sister chromatid
Published in PLoS genetics (01-01-2013)“…DNA double-strand breaks (DSBs) are harmful lesions that arise mainly during replication. The choice of the sister chromatid as the preferential repair…”
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Reversible and irreversible aggregation of magnetic liposomes
Published in Nanoscale (12-10-2017)“…Understanding stabilization and aggregation in magnetic nanoparticle systems is crucial to optimizing the functionality of these systems in real physiological…”
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Formation and characterization of biobased magnetic nanoparticles double coated with dextran and chitosan by layer-by-layer deposition
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (20-05-2014)“…•Biobased particles can be successfully achieved through layer-by-layer deposition.•The first layer deposited determines the size and stability of the…”
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New tools to study DNA double-strand break repair pathway choice
Published in PloS one (14-10-2013)“…A broken DNA molecule is difficult to repair, highly mutagenic, and extremely cytotoxic. Such breaks can be repaired by homology-independent or…”
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CtIP Mutations Cause Seckel and Jawad Syndromes
Published in PLoS genetics (01-10-2011)“…Seckel syndrome is a recessively inherited dwarfism disorder characterized by microcephaly and a unique head profile. Genetically, it constitutes a…”
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The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
Published in Frontiers in molecular biosciences (29-04-2021)“…The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the survival and fitness of any living…”
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The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
Published in Cell reports (Cambridge) (18-09-2018)“…DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination (HR). The decision between these…”
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The interface between transcription and mRNP export: From THO to THSC/TREX-2
Published in Biochimica et biophysica acta (01-08-2010)“…Eukaryotic gene expression is a multilayer process covering transcription to post-translational protein modifications. As the nascent pre-mRNA emerges from the…”
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Bioprecariedad. El poder de las patentes y su impacto en la salud pública
Published in Revista de Bioética y Derecho (01-07-2023)“…El objetivo del presente artículo es analizar el poder de las patentes y su papel en la confrontación actual entre el derecho a la salud (pública) y los…”
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Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery
Published in The Journal of cell biology (23-03-2009)“…The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian cells, binds the tumor…”
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A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
Published in PLoS genetics (05-05-2017)“…Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to DNA double-strand breaks (DSBs) that…”
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Magnetoliposomes prepared by reverse-phase followed by sequential extrusion: Characterization and possibilities in the treatment of inflammation
Published in International journal of pharmaceutics (28-02-2011)“…Anionic ferrofluid was encapsulated in 200 nm-diameter liposomes. The process involved phase-reverse evaporation followed by sequential extrusion…”
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External magnetic field-induced selective biodistribution of magnetoliposomes in mice
Published in Nanoscale research letters (10-08-2012)“…This study looked at the effect of an external magnet on the biodistribution of magnetoliposomes intravenously administrated in mice (8 mg iron/kg) with and…”
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Interdependence between Transcription and mRNP Processing and Export, and Its Impact on Genetic Stability
Published in Molecular cell (10-06-2005)“…The conserved eukaryotic THO-TREX complex acts at the interface between transcription and mRNA export and affects transcription-associated recombination. To…”
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