Search Results - "Jimenez, Maritza A."

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  1. 1

    Lung vaso-occlusion in sickle cell disease mediated by arteriolar neutrophil-platelet microemboli by Bennewitz, Margaret F, Jimenez, Maritza A, Vats, Ravi, Tutuncuoglu, Egemen, Jonassaint, Jude, Kato, Gregory J, Gladwin, Mark T, Sundd, Prithu

    Published in JCI insight (12-01-2017)
    “…In patients with sickle cell disease (SCD), the polymerization of intraerythrocytic hemoglobin S promotes downstream vaso-occlusive events in the…”
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    Journal Article
  2. 2
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    Glycoprotein Ibα inhibitor (CCP-224) prevents neutrophil-platelet aggregation in sickle cell disease by Jimenez, Maritza A., Novelli, Enrico M., Shaw, Gray D., Sundd, Prithu

    Published in Blood advances (12-09-2017)
    “…•CCP-224 attenuates neutrophil-platelet aggregation in SCD patient blood.•CCP-224 has the potential to prevent vaso-occlusion in SCD patients…”
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    Journal Article
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    Neutrophil-Platelet Aggregation Enables Vaso-Occlusion in Sickle Cell Disease by Jimenez, Maritza A., Kato, Gregory J, Sundd, Prithu

    Published in Blood (02-12-2016)
    “…Introduction: Sickle Cell Disease (SCD) is an autosomal-recessive-genetic disorder that leads to sickling and hemolysis of red blood cells (RBCs). Acute…”
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    Journal Article
  6. 6

    Platelet Nucleation on Arrested Neutrophils Drives Vaso-Occlusion in Sickle Cell Disease by Jimenez, Maritza A., Sundd, Prithu, Novelli, Enrico M, Kato, Gregory J

    Published in Blood (03-12-2015)
    “…Introduction: Sickle Cell Disease (SCD) is an autosomal recessive genetic disorder that leads to sickling and hemolysis of RBCs under hypoxic conditions. As a…”
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    Journal Article