Search Results - "Jimenez, Maritza A."
-
1
Lung vaso-occlusion in sickle cell disease mediated by arteriolar neutrophil-platelet microemboli
Published in JCI insight (12-01-2017)“…In patients with sickle cell disease (SCD), the polymerization of intraerythrocytic hemoglobin S promotes downstream vaso-occlusive events in the…”
Get full text
Journal Article -
2
Quantitative microfluidic fluorescence microscopy to study vaso-occlusion in sickle cell disease
Published in Haematologica (Roma) (01-10-2015)Get full text
Journal Article -
3
Glycoprotein Ibα inhibitor (CCP-224) prevents neutrophil-platelet aggregation in sickle cell disease
Published in Blood advances (12-09-2017)“…•CCP-224 attenuates neutrophil-platelet aggregation in SCD patient blood.•CCP-224 has the potential to prevent vaso-occlusion in SCD patients…”
Get full text
Journal Article -
4
Platelet Extracellular Vesicles Drive Inflammasome-IL-1β-Dependent Lung Injury in Sickle Cell Disease
Published in American journal of respiratory and critical care medicine (01-01-2020)“…Intraerythrocytic polymerization of Hb S promotes hemolysis and vasoocclusive events in the microvasculature of patients with sickle cell disease (SCD)…”
Get full text
Journal Article -
5
Neutrophil-Platelet Aggregation Enables Vaso-Occlusion in Sickle Cell Disease
Published in Blood (02-12-2016)“…Introduction: Sickle Cell Disease (SCD) is an autosomal-recessive-genetic disorder that leads to sickling and hemolysis of red blood cells (RBCs). Acute…”
Get full text
Journal Article -
6
Platelet Nucleation on Arrested Neutrophils Drives Vaso-Occlusion in Sickle Cell Disease
Published in Blood (03-12-2015)“…Introduction: Sickle Cell Disease (SCD) is an autosomal recessive genetic disorder that leads to sickling and hemolysis of RBCs under hypoxic conditions. As a…”
Get full text
Journal Article