Search Results - "Jimenez, Consuelo"

Assessment of the PARP inhibitor talazoparib photosafety profile by Mateos-Pujante, Alejandro, Jiménez, M. Consuelo, Andreu, Inmaculada

“…Talazoparib (TLZ) is a poly(adenosine diphosphate [ADP]-ribose) polymerase inhibitor employed for the treatment of breast cancer. This drug displays an…”
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Topological effects in ultrafast photoinduced processes between flurbiprofen and tryptophan in linked dyads and within human serum albumin by Tamarit, Lorena, García-Gabarda, Laura, Jiménez, M Consuelo, Miranda, Miguel A, Vayá, Ignacio

“…The interaction dynamics between flurbiprofen (FBP) and tryptophan (Trp) has been studied in covalently linked dyads and within human serum albumin (HSA) by…”
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Highly Efficient Production of Heteroarene Phosphonates by Dichromatic Photoredox Catalysis by Herrera-Luna, Jorge C, Díaz, David Díaz, Jiménez, M. Consuelo, Pérez-Ruiz, Raúl

“…A new strategy to achieve efficient aerobic phosphorylation of five-membered heteraroenes with excellent yields using dichromatic photoredox catalysis in a…”
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Photogeneration of Quinone Methides as Latent Electrophiles for Lysine Targeting by Pérez-Ruiz, Raúl, Molins-Molina, Oscar, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A, Jiménez, M. Consuelo

“…Latent electrophiles are nowadays very attractive chemical entities for drug discovery, as they are unreactive unless activated upon binding with the specific…”
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Rapid Access to Borylated Thiophenes Enabled by Visible Light by Herrera-Luna, Jorge C, Sampedro, Diego, Jiménez, M. Consuelo, Pérez-Ruiz, Raúl

“…Boron-containing thiophenes are important entities in organic/medicinal chemistry as well as in material science. In this Letter, a novel, straightforward, and…”
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Aerobic Visible-Light-Driven Borylation of Heteroarenes in a Gel Nanoreactor by Herrera-Luna, Jorge C, Díaz Díaz, David, Abramov, Alex, Encinas, Susana, Jiménez, M. Consuelo, Pérez-Ruiz, Raúl

“…Heteroarene boronate esters constitute valuable intermediates in modern organic synthesis. As building blocks, they can be further applied to the synthesis of…”
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Photoactive assemblies of organic compounds and biomolecules: drug-protein supramolecular systems by Vayá, Ignacio, Lhiaubet-Vallet, Virginie, Jiménez, M Consuelo, Miranda, Miguel A

“…The properties of singlet and triplet excited states are strongly medium-dependent. Hence, these species constitute valuable tools as reporters to probe…”
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A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins by Vendrell-Criado, Victoria, González-Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo

“…Binding of the immunosuppressive agent mycophenolate mofetil (MMP) and its pharmacologically active metabolite mycophenolic acid (MPA) to human serum albumin…”
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Effect of Cilastatin on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy by Zaballos, Matilde, Power, Mercedes, Canal-Alonso, María Iluminada, González-Nicolás, María Ángeles, Vasquez-Jimenez, Wenceslao, Lozano-Lominchar, Pablo, Cabrerizo-Torrente, Pilar, Palencia-García, Natividad, Gago-Quiroga, Susana, Ginel-Feito, María Dolores, Jiménez, Consuelo, Lázaro, Alberto, González-Bayón, Luis

“…Cisplatin is one of the most widely used chemotherapeutic agents in oncology, although its nephrotoxicity limits application and dosage. We present the results…”
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Antimicrobial activity of essential oil components against Escherichia coli depends on the food components present in a food matrix by Gómez-Llorente, Héctor, Pérez-Esteve, Édgar, Barat, José M., Jiménez, M. Consuelo, González-Bello, Concepción, Fernández-Segovia, Isabel

“…Despite numerous studies evaluating the antimicrobial activity of essential oil components (EOCs) against different microorganisms, the effect of the…”
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In-Flow Heterogeneous Triplet–Triplet Annihilation Upconversion by Castellanos-Soriano, Jorge, Garnes-Portolés, Francisco, Jiménez, M. Consuelo, Leyva-Pérez, Antonio, Pérez-Ruiz, Raúl

“…Photon upconversion based on triplet–triplet annihilation (TTA-UC) is an attractive wavelength conversion with increasing use in organic synthesis in the…”
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Photobehavior of the antipsychotic drug cyamemazine in a supramolecular gel protective environment by Vendrell-Criado, Victoria, Angulo-Pachón, César A., Miravet, Juan F., Galindo, Francisco, Miranda, Miguel A., Jiménez, M. Consuelo

“…In this work, a molecular hydrogel made of gelator (S)-4-((3-methyl-1-(nonylamino)-1-oxobutan-2-yl)amino)-4-oxobutanoic acid (SVN) has been employed as soft…”
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Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods by Limones-Herrero, Daniel, Palumbo, Fabrizio, Vendrell-Criado, Victoria, Andreu, Inmaculada, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo

“…Transient absorption spectroscopy in combination with in silico methods has been employed to study the interactions between human serum albumin (HSA) and the…”
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Mechanistic Studies on the Photoallergy Mediated by Fenofibric Acid: Photoreactivity with Serum Albumins by Vayá, Ignacio, Andreu, Inmaculada, Monje, Vicente T, Jiménez, M. Consuelo, Miranda, Miguel A

“…The photoreactivity of fenofibric acid (FA) in the presence of human and bovine serum albumins (HSA and BSA, respectively) has been investigated by…”
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A New Pathway for Protein Haptenation by β‐Lactams by Pérez‐Ruíz, Raúl, Lence, Emilio, Andreu, Inmaculada, Limones‐Herrero, Daniel, González‐Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo

“…The covalent binding of β‐lactams to proteins upon photochemical activation has been demonstrated by using an integrated approach that combines photochemical,…”
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Experimental and Theoretical Studies on the Radical-Cation-Mediated Imino-Diels–Alder Reaction by Pérez-Ruiz, Raul, Domingo, Luis R, Jiménez, M. Consuelo, Miranda, Miguel A

“…The feasibility of an electron transfer imino-Diels–Alder reaction between N-benzylideneaniline and arylalkenes in the presence of a pyrylium salt as a…”
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Stereodifferentiation in the Compartmentalized Photooxidation of a Protein-Bound Anthracene by Alonso, Rafael, Jiménez, M. Consuelo, Miranda, Miguel A

“…Encapsulation within transport proteins strongly reduces the photooxidation rate of (S)- and (R)-2-(9-anthracenyl)propanoic acid (1) and results in a…”
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Enhanced Photostability of the Anthracene Chromophore in Aqueous Medium upon Protein Encapsulation by Alonso, Rafael, Yamaji, Minoru, Jiménez, M. Consuelo, Miranda, Miguel A

“…In the present work, 9-anthraceneacetic acid (1) has been selected as a simple, water-compatible derivative of the anthracene chromophore to investigate the…”
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A joint experimental/theoretical study of the ultrafast excited state deactivation of deoxyadenosine and 9-methyladenine in water and acetonitrile by Gustavsson, Thomas, Sarkar, Nilmoni, Vayá, Ignacio, Jiménez, M Consuelo, Markovitsi, Dimitra, Improta, Roberto

“…The excited states of deoxyadenosine (dA) and 9-methyladenine (9Me-Ade) were studied in water and acetonitrile by a combination of steady-state and…”
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Mapping a protein recognition centre with chiral photoactive ligands. An integrated approach combining photophysics, reactivity, proteomics and molecular dynamics simulation studies by Limones-Herrero, Daniel, Pérez-Ruiz, Raúl, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A, Jiménez, M Consuelo

“…A multidisciplinary strategy to obtain structural information on the intraprotein region is described here. As probe ligands, ( )- and ( )- (the methyl esters…”
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