Search Results - "Jimenez, C R"

Breast cancer classification by proteomic technologies: Current state of knowledge by Lam, S.W, Jimenez, C.R, Boven, E

“…Abstract Breast cancer is traditionally considered as a heterogeneous disease. Molecular profiling of breast cancer by gene expression studies has provided us…”
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Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma by Le Large, T Y S, Bijlsma, M F, El Hassouni, B, Mantini, G, Lagerweij, T, Henneman, A A, Funel, N, Kok, B, Pham, T V, de Haas, R, Morelli, L, Knol, J C, Piersma, S R, Kazemier, G, van Laarhoven, H W M, Giovannetti, E, Jimenez, C R

“…Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease, with minimal therapeutic options. Aberrant tyrosine kinase activity influences tumor growth…”
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Fructose metabolism as a common evolutionary pathway of survival associated with climate change, food shortage and droughts by Johnson, R. J., Stenvinkel, P., Andrews, P., Sánchez‐Lozada, L. G., Nakagawa, T., Gaucher, E., Andres‐Hernando, A., Rodriguez‐Iturbe, B., Jimenez, C. R., Garcia, G., Kang, D.‐H., Tolan, D. R., Lanaspa, M. A.

“…Mass extinctions occur frequently in natural history. While studies of animals that became extinct can be informative, it is the survivors that provide clues…”
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Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a single arm intervention study by van den Berg, I, van de Weerd, S, Roodhart, J M L, Vink, G R, van den Braak, R R J Coebergh, Jimenez, C R, Elias, S G, van Vliet, D, Koelink, M, Hong, E, van Grevenstein, W M U, van Oijen, M G H, Beets-Tan, R G H, van Krieken, J H J M, IJzermans, J N M, Medema, J P, Koopman, M

“…It is estimated that around 15-30% of patients with early stage colon cancer benefit from adjuvant chemotherapy. We are currently not capable of upfront…”
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Identification of failure modes in glass/polypropylene composites by means of the primary frequency content of the acoustic emission event by Ramirez-Jimenez, C.R, Papadakis, N, Reynolds, N, Gan, T.H, Purnell, P, Pharaoh, M

“…Tensile test were carried out on glass/polypropylene specimens made in-home, and acoustic emissions were recorded from these tests. Fibre orientation of each…”
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Simple urine storage protocol for extracellular vesicle proteomics compatible with at-home self-sampling by Erozenci, L. A., Pham, T. V., Piersma, S. R., Dits, N. F. J., Jenster, G. W., van Royen, M. E., Moorselaar, R. J. A., Jimenez, C. R., Bijnsdorp, I. V.

“…Urinary extracellular vesicles (EVs) have gained increased interest as a biomarker source. Clinical implementation on a daily basis requires protocols that…”
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Comparative Proteomics of Colon Cancer Stem Cells and Differentiated Tumor Cells Identifies BIRC6 as a Potential Therapeutic Target by Van Houdt, WJ, Emmink, BL, Pham, TV, Piersma, SR, Verheem, A, Vries, RG, Fratantoni, SA, Pronk, A, Clevers, H, Borel Rinkes, IHM, Jimenez, CR, Kranenburg, O

“…Patients with liver metastases from colon carcinoma show highly variable responses to chemotherapy and tumor recurrence is frequently observed…”
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Effect of the number of bilayers in Ti/TiN coatings on AISI 316L deposited by sputtering on their hardness, adhesion, and wear by Santaella-González, J.B., Hernández-Torres, J., Morales-Hernández, J., Flores-Ramírez, N., Ferreira-Palma, C., Rodríguez-Jiménez, R.C., García-González, L.

“…•The nanostructured Ti/TiN multilayer coatings were synthesized by reactive DC sputtering.•The increase of Ti/TiN interfaces favors the increase of the…”
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Simulated linear test applied to quantitative proteomics by Pham, T V, Jimenez, C R

“…Omics studies aim to find significant changes due to biological or functional perturbation. However, gene and protein expression profiling experiments contain…”
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Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer by Snoeren, N, Emmink, B L, Koerkamp, M J G, van Hooff, S R, Goos, J A C M, van Houdt, W J, de Wit, M, Prins, A M, Piersma, S R, Pham, T V, Belt, E J, Bril, H, Stockmann, H B, Meijer, G A, van Hillegersberg, R, Holstege, F C, Jimenez, C R, Fijneman, R J A, Kranenburg, O W, Rinkes, I H M Borel

“…Background: Little is known about the factors that drive metastasis formation in colorectal cancer (CRC). Here, we set out to identify genes and proteins in…”
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Identification of biomarkers for diagnosis and progression of MS by MALDI-TOF mass spectrometry by Teunissen, CE, Koel-Simmelink, MJA, Pham, TV, Knol, JC, Khalil, M, Trentini, A, Killestein, J, Nielsen, J, Vrenken, H, Popescu, V, Dijkstra, CD, Jimenez, CR

“…Introduction: Body fluid biomarkers for clinical subtyping and monitoring of disease progression are of considerable interest in multiple sclerosis (MS)…”
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Brain endothelial cell expression of SPARCL‐1 is specific to chronic multiple sclerosis lesions and is regulated by inflammatory mediators in vitro by Bridel, C., Koel‐Simmelink, M. J. A., Peferoen, L., Derada Troletti, C., Durieux, S., Gorter, R., Nutma, E., Gami, P., Iacobaeus, E., Brundin, L., Kuhle, J., Vrenken, H., Killestein, J., Piersma, S. R., Pham, T. V., De Vries, H. E., Amor, S., Jimenez, C. R., Teunissen, C. E.

“…Aims Cell matrix modulating protein SPARCL‐1 is highly expressed by astrocytes during CNS development and following acute CNS damage. Applying NanoLC‐MS/MS to…”
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The IntAct molecular interaction database in 2012 by Kerrien, Samuel, Aranda, Bruno, Breuza, Lionel, Bridge, Alan, Broackes-Carter, Fiona, Chen, Carol, Duesbury, Margaret, Dumousseau, Marine, Feuermann, Marc, Hinz, Ursula, Jandrasits, Christine, Jimenez, Rafael C., Khadake, Jyoti, Mahadevan, Usha, Masson, Patrick, Pedruzzi, Ivo, Pfeiffenberger, Eric, Porras, Pablo, Raghunath, Arathi, Roechert, Bernd, Orchard, Sandra, Hermjakob, Henning

“…IntAct is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. Two…”
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Effects of IGF‐1 on In Vitro Culture of Bovine Preantral Follicles are Dose‐Dependent by Jimenez, CR, de Azevedo, JL, Silveira, RG, Penitente-Filho, J, Carrascal-Triana, EL, Zolini, AM, Araujo, VR, Torres, CAA, Gonçalves, WG

“…This study aimed at assessing the effect of different concentrations of the growth factor similar to insulin 1 (IGF‐1) in the development, survival and…”
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Effects of Growth Hormone on In Situ Culture of Bovine Preantral Follicles are Dose Dependent by Jimenez, CR, de Azevedo, JL, Silveira, RG, Penitente-Filho, J, Carrascal-Triana, EL, Zolini, AM, Araújo, VR, Torres, CAA

“…Content The objective of this study was to evaluate different concentrations of growth hormone (GH) on the development of bovine preantral follicles cultured…”
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Key biological processes driving metastatic spread of pancreatic cancer as identified by multi-omics studies by Le Large, T.Y.S, Bijlsma, M.F, Kazemier, G, van Laarhoven, H.M.W, Giovannetti, E, Jimenez, C.R

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy, characterized by a high metastatic burden, already at the time of…”
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Co-expression analysis of pancreatic cancer proteome reveals biology and prognostic biomarkers by Mantini, G., Vallés, A. M., Le Large, T. Y. S., Capula, M., Funel, N., Pham, T. V., Piersma, S. R., Kazemier, G., Bijlsma, M. F., Giovannetti, E., Jimenez, C. R.

“…Purpose Despite extensive biological and clinical studies, including comprehensive genomic and transcriptomic profiling efforts, pancreatic ductal…”
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miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivo by Senol, O, Schaaij-Visser, T B M, Erkan, E P, Dorfer, C, Lewandrowski, G, Pham, T V, Piersma, S R, Peerdeman, S M, Ströbel, T, Tannous, B, Saydam, N, Slavc, I, Knosp, E, Jimenez, C R, Saydam, O

“…miR-200a has been implicated in the pathogenesis of meningiomas, one of the most common central nervous system tumors in humans. To identify how miR-200a…”
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Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery by PosthumaDeBoer, J, Piersma, S R, Pham, T V, van Egmond, P W, Knol, J C, Cleton-Jansen, A M, van Geer, M A, van Beusechem, V W, Kaspers, G J L, van Royen, B J, Jiménez, C R, Helder, M N

“…Background: Osteosarcoma (OS) is the most common bone tumour in children and adolescents. Despite aggressive therapy regimens, treatment outcomes are…”
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Neuropeptide expression and processing as revealed by direct matrix-assisted laser desorption ionization mass spectrometry of single neurons by Jiménez, C R, van Veelen, P A, Li, K W, Wildering, W C, Geraerts, W P, Tjaden, U R, van der Greef, J

“…Neuropeptides were directly detected in single identified neurons and the neurohemal area of peptidergic (neuroendocrine) systems in the Lymnaea brain by using…”
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