Search Results - "Jimenez, Alfons"

Analytical sensitivity of current best-in-class malaria rapid diagnostic tests by Jimenez, Alfons, Rees-Channer, Roxanne R, Perera, Rushini, Gamboa, Dionicia, Chiodini, Peter L, González, Iveth J, Mayor, Alfredo, Ding, Xavier C

“…Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of…”
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SARS-CoV-2 Seroprevalence and Antibody Kinetics Among Health Care Workers in a Spanish Hospital After 3 Months of Follow-up by Moncunill, Gemma, Mayor, Alfredo, Santano, Rebeca, Jiménez, Alfons, Vidal, Marta, Tortajada, Marta, Sanz, Sergi, Méndez, Susana, Llupià, Anna, Aguilar, Ruth, Alonso, Selena, Barrios, Diana, Carolis, Carlo, Cisteró, Pau, Chóliz, Eugenia, Cruz, Angeline, Fochs, Silvia, Jairoce, Chenjerai, Hecht, Jochen, Lamoglia, Montserrat, Martínez, Mikel J, Moreno, Javier, Mitchell, Robert A, Ortega, Natalia, Pey, Nuria, Puyol, Laura, Ribes, Marta, Rosell, Neus, Figueroa-Romero, Antía, Sotomayor, Patricia, Torres, Sara, Williams, Sarah, Barroso, Sonia, Vilella, Anna, Trilla, Antoni, Varela, Pilar, Dobaño, Carlota, Garcia-Basteiro, Alberto L

“…Abstract Background At the COVID-19 spring 2020 pandemic peak in Spain, prevalence of SARS-CoV-2 infection in a cohort of 578 randomly selected health care…”
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Changing Trends in P. falciparum Burden, Immunity, and Disease in Pregnancy by Mayor, Alfredo, Bardají, Azucena, Macete, Eusebio, Nhampossa, Tacilta, Fonseca, Ana Maria, González, Raquel, Maculuve, Sonia, Cisteró, Pau, Rupérez, Maria, Campo, Joe, Vala, Anifa, Sigaúque, Betuel, Jiménez, Alfons, Machevo, Sonia, de la Fuente, Laura, Nhama, Abel, Luis, Leopoldina, Aponte, John J, Acácio, Sozinho, Nhacolo, Arsenio, Chitnis, Chetan, Dobaño, Carlota, Sevene, Esperanza, Alonso, Pedro Luis, Menéndez, Clara

“…Great strides have been made in malaria control, but loss of partial immunity may lead to more-severe disease when infection occurs. In this study of pregnant…”
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Plasma MicroRNA Profiling of Plasmodium falciparum Biomass and Association with Severity of Malaria Disease by Gupta, Himanshu, Rubio, Mercedes, Sitoe, Antonio, Varo, Rosauro, Cisteró, Pau, Madrid, Lola, Cuamba, Inocencia, Jimenez, Alfons, Martiáñez-Vendrell, Xavier, Barrios, Diana, Pantano, Lorena, Brimacombe, Allison, Bustamante, Mariona, Bassat, Quique, Mayor, Alfredo

“…Severe malaria (SM) is a major public health problem in malaria-endemic countries. Sequestration of Plasmodium falciparum-infected erythrocytes in vital organs…”
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Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates by Gómez-Pérez, Gloria P, Legarda, Almudena, Muñoz, Jose, Sim, B Kim Lee, Ballester, María Rosa, Dobaño, Carlota, Moncunill, Gemma, Campo, Joseph J, Cisteró, Pau, Jimenez, Alfons, Barrios, Diana, Mordmüller, Benjamin, Pardos, Josefina, Navarro, Mireia, Zita, Cecilia Justino, Nhamuave, Carlos Arlindo, García-Basteiro, Alberto L, Sanz, Ariadna, Aldea, Marta, Manoj, Anita, Gunasekera, Anusha, Billingsley, Peter F, Aponte, John J, James, Eric R, Guinovart, Caterina, Antonijoan, Rosa M, Kremsner, Peter G, Hoffman, Stephen L, Alonso, Pedro L

“…Controlled human malaria infection (CHMI) by mosquito bite is a powerful tool for evaluation of vaccines and drugs against Plasmodium falciparum malaria…”
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Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital by Garcia-Basteiro, Alberto L., Moncunill, Gemma, Tortajada, Marta, Vidal, Marta, Guinovart, Caterina, Jiménez, Alfons, Santano, Rebeca, Sanz, Sergi, Méndez, Susana, Llupià, Anna, Aguilar, Ruth, Alonso, Selena, Barrios, Diana, Carolis, Carlo, Cisteró, Pau, Chóliz, Eugenia, Cruz, Angeline, Fochs, Silvia, Jairoce, Chenjerai, Hecht, Jochen, Lamoglia, Montserrat, Martínez, Mikel J., Mitchell, Robert A., Ortega, Natalia, Pey, Nuria, Puyol, Laura, Ribes, Marta, Rosell, Neus, Sotomayor, Patricia, Torres, Sara, Williams, Sarah, Barroso, Sonia, Vilella, Anna, Muñoz, José, Trilla, Antoni, Varela, Pilar, Mayor, Alfredo, Dobaño, Carlota

“…Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the…”
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Highly Sensitive and Specific Multiplex Antibody Assays To Quantify Immunoglobulins M, A, and G against SARS-CoV-2 Antigens by Dobaño, Carlota, Vidal, Marta, Santano, Rebeca, Jiménez, Alfons, Chi, Jordi, Barrios, Diana, Ruiz-Olalla, Gemma, Rodrigo Melero, Natalia, Carolis, Carlo, Parras, Daniel, Serra, Pau, Martínez de Aguirre, Paula, Carmona-Torre, Francisco, Reina, Gabriel, Santamaria, Pere, Mayor, Alfredo, García-Basteiro, Alberto L, Izquierdo, Luis, Aguilar, Ruth, Moncunill, Gemma

“…Reliable serological tests are required to determine the prevalence of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to…”
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Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies by Dobaño, Carlota, Santano, Rebeca, Jiménez, Alfons, Vidal, Marta, Chi, Jordi, Rodrigo Melero, Natalia, Popovic, Matija, López-Aladid, Rubén, Fernández-Barat, Laia, Tortajada, Marta, Carmona-Torre, Francisco, Reina, Gabriel, Torres, Antoni, Mayor, Alfredo, Carolis, Carlo, García-Basteiro, Alberto L., Aguilar, Ruth, Moncunill, Gemma, Izquierdo, Luis

“…COVID-19 patients elicit strong responses to the nucleocapsid (N) protein of SARS-CoV-2 but binding antibodies are also detected in prepandemic individuals,…”
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Ambient Air Pollution in Relation to SARS-CoV-2 Infection, Antibody Response, and COVID-19 Disease: A Cohort Study in Catalonia, Spain (COVICAT Study) by Kogevinas, Manolis, Castaño-Vinyals, Gemma, Karachaliou, Marianna, Espinosa, Ana, de Cid, Rafael, Garcia-Aymerich, Judith, Carreras, Anna, Cortés, Beatriz, Pleguezuelos, Vanessa, Jiménez, Alfons, Vidal, Marta, O'Callaghan-Gordo, Cristina, Cirach, Marta, Santano, Rebeca, Barrios, Diana, Puyol, Laura, Rubio, Rocío, Izquierdo, Luis, Nieuwenhuijsen, Mark, Dadvand, Payam, Aguilar, Ruth, Moncunill, Gemma, Dobaño, Carlota, Tonne, Cathryn

“…Emerging evidence links ambient air pollution with coronavirus 2019 (COVID-19) disease, an association that is methodologically challenging to investigate. We…”
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SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia by Karachaliou, Marianna, Moncunill, Gemma, Espinosa, Ana, Castaño-Vinyals, Gemma, Rubio, Rocío, Vidal, Marta, Jiménez, Alfons, Prados, Esther, Carreras, Anna, Cortés, Beatriz, Blay, Natàlia, Bañuls, Marc, Pleguezuelos, Vanessa, Melero, Natalia Rodrigo, Serra, Pau, Parras, Daniel, Izquierdo, Luis, Santamaría, Pere, Carolis, Carlo, Papantoniou, Kyriaki, Goldberg, Ximena, Aguilar, Ruth, Garcia-Aymerich, Judith, de Cid, Rafael, Kogevinas, Manolis, Dobaño, Carlota

“…Heterogeneity of the population in relation to infection, COVID-19 vaccination, and host characteristics is likely reflected in the underlying SARS-CoV-2…”
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Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children by Ubillos, Itziar, Ayestaran, Aintzane, Nhabomba, Augusto J, Dosoo, David, Vidal, Marta, Jiménez, Alfons, Jairoce, Chenjerai, Sanz, Hèctor, Aguilar, Ruth, Williams, Nana Aba, Díez-Padrisa, Núria, Mpina, Maximilian, Sorgho, Hermann, Agnandji, Selidji Todagbe, Kariuki, Simon, Mordmüller, Benjamin, Daubenberger, Claudia, Asante, Kwaku Poku, Owusu-Agyei, Seth, Sacarlal, Jahit, Aide, Pedro, Aponte, John J, Dutta, Sheetij, Gyan, Ben, Campo, Joseph J, Valim, Clarissa, Moncunill, Gemma, Dobaño, Carlota

“…The RTS,S/AS01E vaccine provides partial protection against malaria in African children, but immune responses have only been partially characterized and do not…”
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Infection induced SARS-CoV-2 seroprevalence and heterogeneity of antibody responses in a general population cohort study in Catalonia Spain by Karachaliou, Marianna, Moncunill, Gemma, Espinosa, Ana, Castaño-Vinyals, Gemma, Jiménez, Alfons, Vidal, Marta, Santano, Rebeca, Barrios, Diana, Puyol, Laura, Carreras, Anna, Mayer, Leonie, Rubio, Rocío, Cortés, Beatriz, Pleguezuelos, Vanessa, O’Callaghan-Gordo, Cristina, Fossati, Serena, Rivas, Ioar, Casabonne, Delphine, Vrijheid, Martine, Izquierdo, Luis, Aguilar, Ruth, Basagaña, Xavier, Garcia-Aymerich, Judith, de Cid, Rafael, Dobaño, Carlota, Kogevinas, Manolis

“…Sparse data exist on the complex natural immunity to SARS-CoV-2 at the population level. We applied a well-validated multiplex serology test in 5000…”
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Differential Patterns of IgG Subclass Responses to Plasmodium falciparum Antigens in Relation to Malaria Protection and RTS,S Vaccination by Dobaño, Carlota, Santano, Rebeca, Vidal, Marta, Jiménez, Alfons, Jairoce, Chenjerai, Ubillos, Itziar, Dosoo, David, Aguilar, Ruth, Williams, Nana Aba, Díez-Padrisa, Núria, Ayestaran, Aintzane, Valim, Clarissa, Asante, Kwaku Poku, Owusu-Agyei, Seth, Lanar, David, Chauhan, Virander, Chitnis, Chetan, Dutta, Sheetij, Angov, Evelina, Gamain, Benoit, Coppel, Ross L, Beeson, James G, Reiling, Linda, Gaur, Deepak, Cavanagh, David, Gyan, Ben, Nhabomba, Augusto J, Campo, Joseph J, Moncunill, Gemma

“…Naturally acquired immunity (NAI) to malaria is mainly mediated by IgG antibodies but the subclasses, epitope targets and effector functions have not been…”
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Correlates of protection and determinants of SARS-CoV-2 breakthrough infections 1 year after third dose vaccination by Martín Pérez, Carla, Aguilar, Ruth, Jiménez, Alfons, Salmerón, Gemma, Canyelles, Mar, Rubio, Rocío, Vidal, Marta, Cuamba, Inocencia, Barrios, Diana, Díaz, Natalia, Santano, Rebeca, Serra, Pau, Santamaria, Pere, Izquierdo, Luis, Trilla, Antoni, Vilella, Anna, Barroso, Sonia, Tortajada, Marta, García-Basteiro, Alberto L, Moncunill, Gemma, Dobaño, Carlota

“…The emergence of new SARS-CoV-2 variants and the waning of immunity raise concerns about vaccine effectiveness and protection against COVID-19. While antibody…”
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Quantification of malaria antigens PfHRP2 and pLDH by quantitative suspension array technology in whole blood, dried blood spot and plasma by Martiáñez-Vendrell, Xavier, Jiménez, Alfons, Vásquez, Ana, Campillo, Ana, Incardona, Sandra, González, Raquel, Gamboa, Dionicia, Torres, Katherine, Oyibo, Wellington, Faye, Babacar, Macete, Eusebio, Menéndez, Clara, Ding, Xavier C, Mayor, Alfredo

“…Malaria diagnostics by rapid diagnostic test (RDT) relies primarily on the qualitative detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and…”
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Comparison of two malaria multiplex immunoassays that enable quantification of malaria antigens by Jang, Ihn Kyung, Jiménez, Alfons, Rashid, Andrew, Barney, Rebecca, Golden, Allison, Ding, Xavier C, Domingo, Gonzalo J, Mayor, Alfredo

“…Immunoassay platforms that simultaneously detect malaria antigens including histidine-rich protein 2 (HRP2)/HRP3 and Plasmodium lactate dehydrogenase (pLDH),…”
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Long-Term Exposure to Air Pollution and COVID-19 Vaccine Antibody Response in a General Population Cohort (COVICAT Study, Catalonia) by Kogevinas, Manolis, Karachaliou, Marianna, Espinosa, Ana, Aguilar, Ruth, Castaño-Vinyals, Gemma, Garcia-Aymerich, Judith, Carreras, Anna, Cortés, Beatriz, Pleguezuelos, Vanessa, Papantoniou, Kyriaki, Rubio, Rocío, Jiménez, Alfons, Vidal, Marta, Serra, Pau, Parras, Daniel, Santamaría, Pere, Izquierdo, Luis, Cirach, Marta, Nieuwenhuijsen, Mark, Dadvand, Payam, Straif, Kurt, Moncunill, Gemma, de Cid, Rafael, Dobaño, Carlota, Tonne, Cathryn

“…Ambient air pollution has been associated with COVID-19 disease severity and antibody response induced by infection. We examined the association between…”
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RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study by Dobaño, Carlota, Ubillos, Itziar, Jairoce, Chenjerai, Gyan, Ben, Vidal, Marta, Jiménez, Alfons, Santano, Rebeca, Dosoo, David, Nhabomba, Augusto J, Ayestaran, Aintzane, Aguilar, Ruth, Williams, Nana Aba, Díez-Padrisa, Núria, Lanar, David, Chauhan, Virander, Chitnis, Chetan, Dutta, Sheetij, Gaur, Deepak, Angov, Evelina, Asante, Kwaku Poku, Owusu-Agyei, Seth, Valim, Clarissa, Gamain, Benoit, Coppel, Ross L, Cavanagh, David, Beeson, James G, Campo, Joseph J, Moncunill, Gemma

“…Vaccination and naturally acquired immunity against microbial pathogens may have complex interactions that influence disease outcomes. To date, only…”
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Sustained seropositivity up to 20.5 months after COVID-19 by Dobaño, Carlota, Ramírez-Morros, Anna, Alonso, Selena, Rubio, Rocío, Ruiz-Olalla, Gemma, Vidal-Alaball, Josep, Macià, Dídac, Catalina, Queralt Miró, Vidal, Marta, Casanovas, Aina Fuster, Prados de la Torre, Esther, Barrios, Diana, Jiménez, Alfons, Zanoncello, Jasmina, Melero, Natalia Rodrigo, Carolis, Carlo, Izquierdo, Luis, Aguilar, Ruth, Moncunill, Gemma, Ruiz-Comellas, Anna

“…This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a…”
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Chronic malaria exposure is associated with inhibitory markers on T cells that correlate with atypical memory and marginal zone-like B cells by Mitchell, Robert A, Ubillos, Itziar, Requena, Pilar, Campo, Joseph J, Ome-Kaius, Maria, Hanieh, Sarah, Umbers, Alexandra, Samol, Paula, Barrios, Diana, Jiménez, Alfons, Bardají, Azucena, Mueller, Ivo, Menéndez, Clara, Rogerson, Stephen, Dobaño, Carlota, Moncunill, Gemma

“…Chronic immune activation from persistent malaria infections can induce immunophenotypic changes associated with T-cell exhaustion. However, associations…”
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