Search Results - "Jimbu, Laura"

Is There a Place for PD-1-PD-L Blockade in Acute Myeloid Leukemia? by Jimbu, Laura, Mesaros, Oana, Popescu, Cristian, Neaga, Alexandra, Berceanu, Iulia, Dima, Delia, Gaman, Mihaela, Zdrenghea, Mihnea

“…Checkpoint inhibitors were a major breakthrough in the field of oncology. In September 2014, based on the KEYNOTE-001 study, the Food and Drug Administration…”
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MicroRNAs Associated With a Good Prognosis of Acute Myeloid Leukemia and Their Effect on Macrophage Polarization by Neaga, Alexandra, Bagacean, Cristina, Tempescul, Adrian, Jimbu, Laura, Mesaros, Oana, Blag, Cristina, Tomuleasa, Ciprian, Bocsan, Corina, Gaman, Mihaela, Zdrenghea, Mihnea

“…Acute myeloid leukemia (AML) is an aggressive myeloid malignancy with poor outcomes despite very intensive therapeutic approaches. For the majority of patients…”
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Dysregulated MicroRNAs in Chronic Lymphocytic Leukemia by Mesaros, Oana, Veres, Stefana, Onciul, Madalina, Matei, Emilia, Jimbu, Laura, Neaga, Alexandra, Zdrenghea, Mihnea

“…MiRNAs are a class of non-coding RNAs acting as gene expression regulators by modulating the lifespan of messenger RNA. Commonly referred to as the most…”
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The Potential Advantage of Targeting Both PD-L1/PD-L2/PD-1 and IL-10–IL-10R Pathways in Acute Myeloid Leukemia by Jimbu, Laura, Mesaros, Oana, Neaga, Alexandra, Nanut, Ana Maria, Tomuleasa, Ciprian, Dima, Delia, Bocsan, Corina, Zdrenghea, Mihnea

“…Tumor cells promote the suppression of host anti-tumor type 1 T cell responses by various mechanisms, including the upregulation of surface inhibitory…”
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MicroRNAs Associated with a Bad Prognosis in Acute Myeloid Leukemia and Their Impact on Macrophage Polarization by Jimbu, Laura, Mesaros, Oana, Joldes, Corina, Neaga, Alexandra, Zaharie, Laura, Zdrenghea, Mihnea

“…MicroRNAs (miRNAs) are short, non-coding ribonucleic acids (RNAs) associated with gene expression regulation. Since the discovery of the first miRNA in 1993,…”
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Macrophages as Potential Therapeutic Targets in Acute Myeloid Leukemia by Mesaros, Oana, Onciul, Madalina, Matei, Emilia, Joldes, Corina, Jimbu, Laura, Neaga, Alexandra, Serban, Oana, Zdrenghea, Mihnea, Nanut, Ana Maria

“…Acute myeloid leukemia (AML) is a heterogenous malignant hemopathy, and although new drugs have emerged recently, current treatment options still show limited…”
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Macrophage Polarization in Chronic Lymphocytic Leukemia: Nurse-Like Cells Are the Caretakers of Leukemic Cells by Mesaros, Oana, Jimbu, Laura, Neaga, Alexandra, Popescu, Cristian, Berceanu, Iulia, Tomuleasa, Ciprian, Fetica, Bogdan, Zdrenghea, Mihnea

“…Macrophages are terminally differentiated innate immune cells. Through their activation, they can be polarized towards the pro-inflammatory M1 type or the…”
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A Survival Analysis of Acute Myeloid Leukemia Patients Treated With Intensive Chemotherapy: A Single Center Experience by Jimbu, Laura, Valeanu, Madalina, Adrian, Trifa, Mesaros, Oana, Bojan, Anca, Dima, Delia, Parvu, Andrada, Rus, Ioana C, Tomuleasa, Ciprian, Torok, Tunde, Urian, Laura, Vasilache, Anca, Zdrenghea, Mihnea

“…Introduction: Acute myeloid leukaemia (AML) is a haematological disease associated with a dismal prognosis, despite major progress made in recent years in…”
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Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients? by Popescu, Cristian-Marian, Ursache, Aurora Livia, Feketea, Gavriela, Bocsan, Corina, Jimbu, Laura, Mesaros, Oana, Edwards, Michael, Wang, Hongwei, Berceanu, Iulia, Neaga, Alexandra, Zdrenghea, Mihnea

“…Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively…”
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Children With Acute Lymphoblastic Leukemia in Romania: Results From a Decade-Long Single-Center Study by Neaga, Alexandra, Jimbu, Laura, Mesaros, Oana, Blag, Cristina, Zdrenghea, Mihnea

“…Acute lymphoblastic leukemia (ALL) is the most prevalent cancer in children, with continuously improving survival rates. As few studies in Romania have…”
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Why Do Children with Acute Lymphoblastic Leukemia Fare Better Than Adults? by Neaga, Alexandra, Jimbu, Laura, Mesaros, Oana, Bota, Madalina, Lazar, Diana, Cainap, Simona, Blag, Cristina, Zdrenghea, Mihnea

“…It is a new and exciting time for acute lymphoblastic leukemia (ALL). While nearly 50 years ago, only one in nine children with ALL survived with chemotherapy,…”
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Association of TLR4 Rs4986791 Polymorphism and TLR9 Haplotypes with Acute Myeloid Leukemia Susceptibility: A Case-Control Study of Adult Patients by Banescu, Claudia, Tripon, Florin, Bojan, Anca S, Trifa, Adrian P, Muntean, Carmen, Crauciuc, George Andrei, Boglis, Alina, Candea, Marcela, Lazar, Erzsebet, Jimbu, Laura, Iancu, Mihaela

“…Toll-like receptors (TLRs) have an important role in innate immunity, and single nucleotide polymorphisms (SNPs) of genes influence the risk of developing…”
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Association Analysis of TP53 rs1042522, MDM2 rs2279744, rs3730485, MDM4 rs4245739 Variants and Acute Myeloid Leukemia Susceptibility, Risk Stratification Scores, and Clinical Features: An Exploratory Study by Tripon, Florin, Iancu, Mihaela, Trifa, Adrian, Crauciuc, George Andrei, Boglis, Alina, Balla, Beata, Cosma, Adriana, Dima, Delia, Candea, Marcela, Lazar, Erzsebet, Jimbu, Laura, Banescu, Claudia

“…This study aimed to explore the associations between the TP53 rs1042522 (TP53 Arg72Pro), MDM2 rs2279744 (MDM2 309T>G), rs3730485 (MDM2 del1518), MDM4 rs4245739…”
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