Search Results - "Jima, D"

A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes by Doss, Jennifer F, Corcoran, David L, Jima, Dereje D, Telen, Marilyn J, Dave, Sandeep S, Chi, Jen-Tsan

“…Human erythrocytes are terminally differentiated, anucleate cells long thought to lack RNAs. However, previous studies have shown the persistence of many…”
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Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children by Cowley, Michael, Skaar, David A, Jima, Dereje D, Maguire, Rachel L, Hudson, Kathleen M, Park, Sarah S, Sorrow, Patricia, Hoyo, Cathrine

“…Imprinted genes are defined by their preferential expression from one of the two parental alleles. This unique mode of gene expression is dependent on…”
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Genomic map of candidate human imprint control regions: the imprintome by Jima, Dereje D., Skaar, David A., Planchart, Antonio, Motsinger-Reif, Alison, Cevik, Sebnem E., Park, Sarah S., Cowley, Michael, Wright, Fred, House, John, Liu, Andy, Jirtle, Randy L., Hoyo, Cathrine

“…Imprinted genes - critical for growth, metabolism, and neuronal function - are expressed from one parental allele. Parent-of-origin-dependent CpG methylation…”
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Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior by Hudson, Kathleen M., Shiver, Emily, Yu, Jianshi, Mehta, Sanya, Jima, Dereje D., Kane, Maureen A., Patisaul, Heather B., Cowley, Michael

“…Cadmium (Cd) is a ubiquitous toxic heavy metal of major public concern. Despite inefficient placental transfer, maternal Cd exposure impairs fetal growth and…”
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Patterns of microRNA expression characterize stages of human B-cell differentiation by Zhang, Jenny, Jima, Dereje D., Jacobs, Cassandra, Fischer, Randy, Gottwein, Eva, Huang, Grace, Lugar, Patricia L., Lagoo, Anand S., Rizzieri, David A., Friedman, Daphne R., Weinberg, J. Brice, Lipsky, Peter E., Dave, Sandeep S.

“…Mature B-cell differentiation provides an important mechanism for the acquisition of adaptive immunity. Malignancies derived from mature B cells constitute the…”
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Isolation and characterization of a novel Rickettsia species (Rickettsia asembonensis sp. nov.) obtained from cat fleas (Ctenocephalides felis) by Maina, Alice N, Luce-Fedrow, Alison, Omulo, Sylvia, Hang, Jun, Chan, Teik-Chye, Ade, Fredrick, Jima, Dereje D, Ogola, Eric, Ge, Hong, Breiman, Robert F, Njenga, Moses K, Richards, Allen L

“…A novel rickettsial agent, 'Candidatus Rickettsia asembonensis' strain NMRCiiT, was isolated from cat fleas, Ctenocephalides felis, from Kenya. Genotypic…”
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LncRNA Tuna is activated in cadmium-induced placental insufficiency and drives the NRF2-mediated oxidative stress response by Simmers, Mark D, Jima, Dereje D, Tsuji, Yoshiaki, Cowley, Michael

“…Cadmium (Cd) is a toxic heavy metal found throughout the environment and one of the top ten toxicants of major public health concern identified by the World…”
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A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics by House, John S, Grimm, Fabian A, Jima, Dereje D, Zhou, Yi-Hui, Rusyn, Ivan, Wright, Fred A

“…Cell-based assays are an attractive option to measure gene expression response to exposure, but the cost of whole-transcriptome RNA sequencing has been a…”
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C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors by House, John S., Gray, Sophia, Owen, Jennifer R., Jima, Dereje D., Smart, Robert C., Hall, Jonathan R.

“…The skin is the first line of defense to cutaneous microbes and viruses, and epidermal keratinocytes play a critical role in preventing infection by viruses…”
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DNA methylation of imprint control regions associated with Alzheimer's disease in non-Hispanic Blacks and non-Hispanic Whites by Cevik, Sebnem E, Skaar, David A, Jima, Dereje D, Liu, Andy J, Østbye, Truls, Whitson, Heather E, Jirtle, Randy L, Hoyo, Cathrine, Planchart, Antonio

“…Alzheimer's disease (AD) prevalence is twice as high in non-Hispanic Blacks (NHBs) as in non-Hispanic Whites (NHWs). The objective of this study was to…”
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PAK1 Mediates Resistance to PI3K Inhibition in Lymphomas by WALSH, Katherine, MCKINNEY, Matthew S, LOVE, Cassandra, QINGQUAN LIU, FAN, Alice, PATEL, Amee, SMITH, Jason, BEAVEN, Anne, JIMA, Dereje D, DAVE, Sandeep S

“…The phosphoinositide 3-kinase (PI3K) pathway is known to play an active role in many malignancies. The role of PI3K inhibition in the treatment of lymphomas…”
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Creation and validation of the first infinium DNA methylation array for the human imprintome by Carreras-Gallo, Natalia, Dwaraka, Varun B., Jima, Dereje D., Skaar, David A., Mendez, Tavis L., Planchart, Antonio, Zhou, Wanding, Jirtle, Randy L., Smith, Ryan, Hoyo, Cathrine

“…Abstract Background Differentially methylated imprint control regions (ICRs) regulate the monoallelic expression of imprinted genes. Their epigenetic…”
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Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis by Reaves, Denise K, Hoadley, Katherine A, Fagan-Solis, Katerina D, Jima, Dereje D, Bereman, Michael, Thorpe, Lynnelle, Hicks, Jyla, McDonald, David, Troester, Melissa A, Perou, Charles M, Fleming, Jodie M

“…Lipolysis-stimulated lipoprotein receptor (LSR) has been found in the plasma membrane and is believed to function in lipoprotein endocytosis and tight…”
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Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting by Longo, Nancy S., Lugar, Patricia L., Yavuz, Sule, Zhang, Wen, Krijger, Peter H.L., Russ, Daniel E., Jima, Dereje D., Dave, Sandeep S., Grammer, Amrie C., Lipsky, Peter E.

“…Subjects with X-linked hyper-IgM syndrome (X-HIgM) have a markedly reduced frequency of CD27+ memory B cells, and their Ig genes have a low level of somatic…”
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Risk factors for anemia in children under 6 years of age in Ethiopia: analysis of the data from the cross-sectional Malaria Indicator Survey, 2007 by Reithinger, R., Ngondi, J.M., Graves, P.M., Hwang, J., Getachew, A., Jima, D.

“…Background Malaria is a leading cause of morbidity in Ethiopia. However, its transmission varies in both space and time, and large areas of the country are…”
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Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines by Grossman, Lisa, Chang, Chris, Dai, Joanne, Nikitin, Pavel A, Jima, Dereje D, Dave, Sandeep S, Luftig, Micah A

“…Epstein-Barr virus (EBV), an oncogenic herpesvirus, infects and transforms primary B cells into immortal lymphoblastoid cell lines (LCLs), providing a model…”
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The Arsenic Resistance-Associated Listeria Genomic Island LGI2 Exhibits Sequence and Integration Site Diversity and a Propensity for Three Listeria monocytogenes Clones with Enhanced Virulence by Lee, Sangmi, Ward, Todd J, Jima, Dereje D, Parsons, Cameron, Kathariou, Sophia

“…In the foodborne pathogen , arsenic resistance is encountered primarily in serotype 4b clones considered to have enhanced virulence and is associated with an…”
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Enhanced transcription of complement and coagulation genes in the absence of adaptive immunity by Jima, Dereje D., Shah, Radhika N., Orcutt, Timothy M., Joshi, Deepa, Law, J. McHugh, Litman, Gary W., Trede, Nikolaus S., Yoder, Jeffrey A.

“…A recessive nonsense mutation in the zebrafish recombination activating gene 1 (rag1) gene results in defective V(D)J recombination; however, animals…”
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The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease by Riegl, Sierra D, Starnes, Cassie, Jima, Dereje D, Baptissart, Marine, Diehl, Anna Mae, Belcher, Scott M, Cowley, Michael

“…Abstract Cadmium (Cd) exposure in adulthood is associated with nonalcoholic fatty liver disease (NAFLD), characterized by steatosis, inflammation, and…”
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Salinity-induced ionoregulatory changes in the gill proteome of the mayfly, Neocloeon triangulifer by Orr, Sarah E., Collins, Leonard B., Jima, Dereje D., Buchwalter, David B.

“…Ecologists have observed declines in the biodiversity of sensitive freshwater organisms in response to increasing concentrations of major ions (salinization)…”
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