Search Results - "Jiménez‐Díaz, Lydia"

Spatial Memory Training Counteracts Hippocampal GIRK Channel Decrease in the Transgenic APPSw,Ind J9 Alzheimer’s Disease Mouse Model by Temprano-Carazo, Sara, Contreras, Ana, Saura, Carlos A., Navarro-López, Juan D., Jiménez-Díaz, Lydia

“…G-protein-gated inwardly rectifying potassium (GIRK) channels are critical determinants of neuronal excitability. They have been proposed as potential targets…”
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Role of GirK Channels in Long-Term Potentiation of Synaptic Inhibition in an In Vivo Mouse Model of Early Amyloid- β Pathology by Sánchez-Rodríguez, Irene, Gruart, Agnès, Delgado-García, José María, Jiménez-Díaz, Lydia, Navarro-López, Juan D

“…Imbalances of excitatory/inhibitory synaptic transmission occur early in the pathogenesis of Alzheimer's disease (AD), leading to hippocampal hyperexcitability…”
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ALZMETA.APP: ONLINE META-ANALYSIS OF MONOCLONAL ANTIBODIES AGAINST AMYLOID-BETA PEPTIDES IN LARGE PHASE III CLINICAL TRIALS IN ALZHEIMER'S DISEASE by Jeremic, Danko, Navarro-López, Juan D., Jiménez-Díaz, Lydia

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PROTEOME IMAGING USING MALDI IN AN ALZHEIMER’S DISEASE MOUSE MODEL: DIFFERENTIAL EXPRESSION OF MEMORY-RELATED HIPPOCAMPAL PROTEINS IN FEMALE AND MALE MICE by Contreras, Ana, Jiménez-Herrera, Raquel, Djebari, Souhail, Navarro-López, Juan D., Jiménez-Díaz, Lydia

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Systematic characterization of a non-transgenic Aβ 1–42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice by Raquel Jiménez-Herrera, Ana Contreras, Souhail Djebari, Jaime Mulero-Franco, Guillermo Iborra-Lázaro, Danko Jeremic, Juan Navarro-López, Lydia Jiménez-Díaz

“…Abstract Background The amyloid-β (Aβ) cascade is one of the most studied theories linked to AD. In multiple models, Aβ accumulation and dyshomeostasis have…”
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SIGMA-1 RECEPTOR ACTIVATION PRESERVES HIPPOCAMPAL SYNAPTIC PLASTICITY AND HIPPOCAMPAL-DEPENDENT CONTEXTUAL AND SOCIAL MEMORY IN AN EARLY AMYLOIDOPATHY MOUSE MODEL by Djebari, Souhail, Jiménez-Hererra, Raquel, Iborra-Lázaro, Guillermo, Jiménez-Díaz, Lydia, Navarro-López, Juan D.

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SYSTEMATIC CHARACTERIZATION OF A NON-TRANSGENIC AΒ1–42 AMYLOIDOSIS MODEL: SYNAPTIC PLASTICITY AND MEMORY DEFICITS IN FEMALE AND MALE MICE by Jiménez-Hererra, Raquel, Contreras, Ana, Iborra-Lázaro, Guillermo, Jeremic, Danko, Djebari, Souhail, Navarro-López, Juan D., Jiménez-Díaz, Lydia

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VU0810464, A GIRK CHANNEL ACTIVATOR, COUNTERACTS SYNAPTIC PLASTICITY AND VISUO-SPATIAL MEMORY IMPAIRMENTS IN AN EARLY AMYLOIDOPATHY MOUSE MODEL by Franco, Jaime Mulero, Jiménez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Iborra-Lázaro, Guillermo, Jiménez-Díaz, Lydia, Navarro-López, Juan D.

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NEW INSIGHTS INTO CPT1C FUNCTIONS RELATED TO LEARNING AND MEMORY: FROM SYNAPSES TO BEHAVIOR by Lázaro, Guillermo Iborra, Djebari, Souhail, Sánchez-Rodríguez, Irene, Gratacòs-Batlle, Esther, Sánchez-Fernández, Nuria, Radosevic, Marija, Casals, Nuria, Navarro-López, Juan D., Soto, David, Jiménez-Díaz, Lydia

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EXPLORING THE LINK BETWEEN CPT1C, AMPA RECEPTORS EXPRESSION AND NOCICEPTION by Castellanos, Aida, Picañol, Javier, Gratacòs-Batlle, Esther, Rimbaut, Maud, Casals, Nuria, Gasull, Xavier, Navarro-López, Juan D., Jiménez-Díaz, Lydia, Soto, David

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Hippocampal long‐term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G‐protein‐gated inwardly rectifying potassium channel activity by Sánchez‐Rodríguez, Irene, Djebari, Souhail, Temprano‐Carazo, Sara, Vega‐Avelaira, David, Jiménez‐Herrera, Raquel, Iborra‐Lázaro, Guillermo, Yajeya, Javier, Jiménez‐Díaz, Lydia, Navarro‐López, Juan D.

“…Hippocampal synaptic plasticity disruption by amyloid‐β (Aβ) peptides + thought to be responsible for learning and memory impairments in Alzheimer's disease…”
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Systematic review and meta analysis of cross immunity and the smokers paradox in COVID19 by Gonzalez-Rubio, Jesús, Navarro-López, Juan D., Jiménez-Díaz, Lydia, Najera, Alberto

“…COVID-19 pandemic, caused by the novel SARS-CoV-2 virus, has raised significant interest in understanding potential cross-immunity mechanisms. Recent evidence…”
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CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non‐associative learning by Iborra‐Lázaro, Guillermo, Djebari, Souhail, Sánchez‐Rodríguez, Irene, Gratacòs‐Batlle, Esther, Sánchez‐Fernández, Nuria, Radošević, Marija, Casals, Núria, Navarro‐López, Juan de Dios, Soto del Cerro, David, Jiménez‐Díaz, Lydia

“…Carnitine palmitoyltransferase 1c (CPT1C) is a neuron‐specific protein widely distributed throughout the CNS and highly expressed in discrete brain areas…”
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Amyloid-β(25-35) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus by Mayordomo-Cava, Jennifer, Yajeya, Javier, Navarro-López, Juan D, Jiménez-Díaz, Lydia

“…During early stages of Alzheimer's disease (AD), synaptic dysfunction induced by toxic amyloid-β (Aβ) is present before the accumulation of histopathological…”
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Recognition Memory Induces Natural LTP-like Hippocampal Synaptic Excitation and Inhibition by Sánchez-Rodríguez, Irene, Temprano-Carazo, Sara, Jeremic, Danko, Delgado-Garcia, Jose Maria, Gruart, Agnès, Navarro-López, Juan D., Jiménez-Díaz, Lydia

“…Synaptic plasticity is a cellular process involved in learning and memory by which specific patterns of neural activity adapt the synaptic strength and…”
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Anti-amyloid antibodies in Alzheimer's disease: what did clinical trials teach us? by Jeremic, Danko, Jiménez-Díaz, Lydia, Navarro-López, Juan D

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A Rapamycin-Sensitive Signaling Pathway Is Essential for the Full Expression of Persistent Pain States by Geranton, Sandrine M, Jimenez-Diaz, Lydia, Torsney, Carole, Tochiki, Keri K, Stuart, Sarah A, Leith, J. Lianne, Lumb, Bridget M, Hunt, Stephen P

“…Translational control through the mammalian target of rapamycin (mTOR) is critical for synaptic plasticity, cell growth, and axon guidance. Recently, it was…”
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Sex differences in Alzheimer's disease: an urgent research venue to follow by Jiménez-Herrera, Raquel, Contreras, Ana, Navarro-López, Juan D, Jiménez-Díaz, Lydia

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Acquisition-dependent modulation of hippocampal neural cell adhesion molecules by associative motor learning by Navarro-López, Juan D, Contreras, Ana, Touyarot, Katia, Herrero, Ana I, Venero, César, Cambon, Karine, Gruart, Agnés, Delgado-García, José M, Sandi, Carmen, Jiménez-Díaz, Lydia

“…It is widely accepted that some types of learning involve structural and functional changes of hippocampal synapses. Cell adhesion molecules neural cell…”
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Local translation in primary afferent fibers regulates nociception by Jiménez-Díaz, Lydia, Géranton, Sandrine M, Passmore, Gayle M, Leith, J Lianne, Fisher, Amy S, Berliocchi, Laura, Sivasubramaniam, Anantha K, Sheasby, Anne, Lumb, Bridget M, Hunt, Stephen P

“…Recent studies have demonstrated the importance of local protein synthesis for neuronal plasticity. In particular, local mRNA translation through the mammalian…”
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