Search Results - "Jiménez, M. Ángeles"
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1
Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity
Published in Journal of medicinal chemistry (12-11-2015)“…In silico dissection of crotalicidin (Ctn), a cathelicidin from a South American pit viper, yielded fragments Ctn[1–14] and Ctn[15–34], which were tested to…”
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2
The C-Terminus of Panusin, a Lobster β-Defensin, Is Crucial for Optimal Antimicrobial Activity and Serum Stability
Published in Pharmaceutics (01-06-2023)“…β-defensins are one of the most abundant and studied families of antimicrobial peptides (AMPs). Because of their selective toxicity to bacterial membranes and…”
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3
Comparison of Two Commercially Available Gamma Interferon Blood Tests for Immunodiagnosis of Tuberculosis
Published in Clinical and Vaccine Immunology (01-01-2008)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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4
Roles of Amphipathicity and Hydrophobicity in the Micelle‐Driven Structural Switch of a 14‐mer Peptide Core from a Choline‐Binding Repeat
Published in Chemistry : a European journal (17-04-2018)“…Choline‐binding repeats (CBRs) are ubiquitous sequences with a β‐hairpin core that are found in the surface proteins of several microorganisms such as S…”
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5
The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region
Published in The Journal of biological chemistry (22-05-2015)“…The membrane-proximal external region (MPER) C-terminal segment and the transmembrane domain (TMD) of gp41 are involved in HIV-1 envelope glycoprotein-mediated…”
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6
A new allele in the BMP15 gene (FecX) that affects prolificacy co-segregates with FecX and FecX in Rasa aragonesa sheep
Published in Theriogenology (01-03-2020)“…A FecX-mutated allele called FecX(R) in the BMP15 gene has been described in Rasa aragonesa sheep. FecX(R) causes increased prolificacy when heterozygous and…”
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7
Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface
Published in Scientific reports (01-12-2016)“…The mechanism by which the HIV-1 MPER epitope is recognized by the potent neutralizing antibody 10E8 at membrane interfaces remains poorly understood. To solve…”
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8
Genetic heterogeneity of dolphin morbilliviruses detected in the Spanish Mediterranean in inter-epizootic period
Published in BMC veterinary research (24-08-2018)“…In the last 20 years, Cetacean Morbillivirus (CeMV) has been responsible for many die-offs in marine mammals worldwide, as clearly exemplified by the three…”
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9
eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1, and self-assembly
Published in Frontiers in molecular biosciences (23-09-2022)“…Yeast eIF4G1 interacts with RNA binding proteins (RBPs) like Pab1 and Pub1 affecting its function in translation initiation and stress granules formation. We…”
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10
DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target
Published in Bioorganic chemistry (01-10-2021)“…[Display omitted] •DD04107 (Pal-EEMQRR-NH2) inhibits α-CGRP exocytotic release.•Ala-scanning indicated that residues E1, M3, Q4 and R6 are crucial for…”
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11
Emergence of structure through protein–protein interactions and pH changes in dually predicted coiled-coil and disordered regions of centrosomal proteins
Published in Biochimica et biophysica acta. Proteins and proteomics (01-10-2014)“…Human centrosomal proteins show a significant, 3.5 fold, bias to be both unstructured and coiled-coils with respect to generic human proteins, based on results…”
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12
Sequence Inversion and Phenylalanine Surrogates at the β-Turn Enhance the Antibiotic Activity of Gramicidin S
Published in Journal of medicinal chemistry (27-05-2010)“…A series of gramicidin S (GS) analogues have been synthesized where the Phe (i + 1) and Pro (i + 2) residues of the β-turn have been swapped while the…”
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13
Therapeutic Index of Gramicidin S is Strongly Modulated by d-Phenylalanine Analogues at the β-Turn
Published in Journal of medicinal chemistry (12-02-2009)“…Analogues of the cationic antimicrobial peptide gramicidin S (GS), cyclo(Val-Orn-Leu-d-Phe-Pro)2, with d-Phe residues replaced by different (restricted…”
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14
Heritage and minority languages, and their learning: A general bibliometric approach and content analysis
Published in Training, language and culture (Online) (15-03-2023)“…The cultural and linguistic diversity that characterises our current society has led to different ways of considering languages and their status in their…”
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15
Influence of the Ovine Genital Tract Microbiota on the Species Artificial Insemination Outcome. A Pilot Study in Commercial Sheep Farms
Published in Biotech (Basel) (06-07-2020)“…To date, there is a lack of research into the vaginal and sperm microbiome and its bearing on artificial insemination (AI) success in the ovine species. Using…”
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16
The Effect of Soil Management on Olive Yield and VOO Quality in a Rainfed Olive Grove of Central Spain
Published in Journal of chemistry (01-01-2016)“…Rainfed olive groves have been traditionally tilled in order to reduce the competition for water and nutrients. In sloping Mediterranean olive groves, this…”
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17
Regulation of formin INF2 and its alteration in INF2-linked inherited disorders
Published in Cellular and molecular life sciences : CMLS (01-12-2024)“…Formins are proteins that catalyze the formation of linear filaments made of actin. INF2, a formin, is crucial for correct vesicular transport, microtubule…”
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18
Cyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor
Published in Bioorganic & medicinal chemistry letters (01-01-2012)“…Based on β-turn-like BDNF loops 2 and 4, involved in receptor interaction, cyclic peptide replicas were designed, synthesized and tested. In addition to the…”
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Design and structural characterisation of monomeric water-soluble α-helix and β-hairpin peptides: State-of-the-art
Published in Archives of biochemistry and biophysics (01-01-2019)“…Peptides are not only useful models for the structural understanding of protein folding and stability but also provide promising therapeutic avenues for the…”
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20
Development and Evaluation of an NTM-IGRA to Guide Pediatric Lymphadenitis Diagnosis
Published in The Pediatric infectious disease journal (01-03-2024)“…Diagnosis of nontuberculous mycobacteria (NTM) infections remains a challenge. In this study, we describe the evaluation of an immunological NTM-interferon…”
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