Search Results - "Jiménez, M. Angeles"

Design and structural characterisation of monomeric water-soluble α-helix and β-hairpin peptides: State-of-the-art by Morales, Paula, Jiménez, M. Angeles

“…Peptides are not only useful models for the structural understanding of protein folding and stability but also provide promising therapeutic avenues for the…”
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Effect of Phosphorylation on the Structural Behaviour of Peptides Derived from the Intrinsically Disordered C‐Terminal Domain of Histone H1.0 by Chaves‐Arquero, Belén, Pérez‐Cañadillas, José M., Jiménez, M. Angeles

“…To investigate the structural impact of phosphorylation on the human histone H1.0 C‐terminal domain, we performed NMR structural studies of model peptides…”
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Turncoat Polypeptides: We Adapt to Our Environment by Zamora‐Carreras, Héctor, Maestro, Beatriz, Sanz, Jesús M., Jiménez, M. Angeles

“…A common interpretation of Anfinsen's hypothesis states that one amino acid sequence should fold into a single, native, ordered state, or a highly similar set…”
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Insights Into the Micelle-Induced β-Hairpin-to-α-Helix Transition of a LytA-Derived Peptide by Photo-CIDNP Spectroscopy by Gomez, M. Victoria, Ruiz-Castañeda, Margarita, Nitschke, Philipp, Gschwind, Ruth M., Jiménez, M. Angeles

“…A choline-binding module from pneumococcal LytA autolysin, LytA239–252, was reported to have a highly stable nativelike β-hairpin in aqueous solution, which…”
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First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases by Borroto, Aldo, Reyes-Garau, Diana, Jiménez, M Angeles, Carrasco, Esther, Moreno, Beatriz, Martínez-Pasamar, Sara, Cortés, José R, Perona, Almudena, Abia, David, Blanco, Soledad, Fuentes, Manuel, Arellano, Irene, Lobo, Juan, Heidarieh, Haleh, Rueda, Javier, Esteve, Pilar, Cibrián, Danay, Martinez-Riaño, Ana, Mendoza, Pilar, Prieto, Cristina, Calleja, Enrique, Oeste, Clara L, Orfao, Alberto, Fresno, Manuel, Sánchez-Madrid, Francisco, Alcamí, Antonio, Bovolenta, Paola, Martín, Pilar, Villoslada, Pablo, Morreale, Antonio, Messeguer, Angel, Alarcon, Balbino

“…Modulating T cell activation is critical for treating autoimmune diseases but requires avoiding concomitant opportunistic infections. Antigen binding to the T…”
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Structure and function of the N-terminal extension of the formin INF2 by Labat-de-Hoz, Leticia, Comas, Laura, Rubio-Ramos, Armando, Casares-Arias, Javier, Fernández-Martín, Laura, Pantoja-Uceda, David, Martín, M. Teresa, Kremer, Leonor, Jiménez, M. Angeles, Correas, Isabel, Alonso, Miguel A.

“…In INF2—a formin linked to inherited renal and neurological disease in humans—the DID is preceded by a short N-terminal extension of unknown structure and…”
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NMR Insights into the Structure-Function Relationships in the Binding of Melanocortin Analogues to the MC1R Receptor by Morais, Maurício, Zamora-Carreras, Héctor, Raposinho, Paula D, Oliveira, Maria Cristina, Pantoja-Uceda, David, Correia, João D G, Jiménez, M Angeles

“…Linear and cyclic analogues of the α-melanocyte stimulating hormone (α-MSH) targeting the human melanocortin receptor 1 (MC1R) are of pharmacological interest…”
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Peptides Mimicking the β7/β8 Loop of HIV‑1 Reverse Transcriptase p51 as “Hotspot-Targeted” Dimerization Inhibitors by Sánchez-Murcia, Pedro A, de Castro, Sonia, García-Aparicio, Carlos, Jiménez, M. Angeles, Corona, Angela, Tramontano, Enzo, Sluis-Cremer, Nicolas, Menéndez-Arias, Luis, Velázquez, Sonsoles, Gago, Federico, Camarasa, María-José

“…A conformationally constrained short peptide designed to target a protein–protein interaction hotspot in HIV-1 reverse transcriptase (RT) disrupts p66-p51…”
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Context-Dependence of the Contribution of Disulfide Bonds to β-Hairpin Stability by Santiveri, Clara M., León, Esther, Rico, Manuel, Jiménez, M. Angeles

“…Incorporation of disulfide bonds to stabilize protein and peptide structures is not always a successful strategy. To advance current knowledge on the…”
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Design and Structure of an Equilibrium Protein Folding Intermediate: A Hint into Dynamical Regions of Proteins by Ayuso-Tejedor, Sara, Angarica, Vladimir Espinosa, Bueno, Marta, Campos, Luis A., Abián, Olga, Bernadó, Pau, Sancho, Javier, Jiménez, M. Angeles

“…Partly unfolded protein conformations close to the native state may play important roles in protein function and in protein misfolding. Structural analyses of…”
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Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides by Morales, Paula, Bruix, Marta, Jiménez, M Angeles

“…Activation of the cannabinoid CB1 receptor induces different cellular signaling cascades through coupling to different effector proteins (G-proteins and…”
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Frontispiece: Effect of Phosphorylation on the Structural Behaviour of Peptides Derived from the Intrinsically Disordered C‐Terminal Domain of Histone H1.0 by Chaves‐Arquero, Belén, Pérez‐Cañadillas, José M., Jiménez, M. Angeles

“…TPKK versus TPVK phosphorylation motifs: Based on NMR data of model peptides, these phosphorylation motifs that are present in the intrinsically disordered…”
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Structural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity by Falcao, Claudio Borges, Pérez-Peinado, Clara, de la Torre, Beatriz G, Mayol, Xavier, Zamora-Carreras, Héctor, Jiménez, M. Ángeles, Rádis-Baptista, Gandhi, Andreu, David

“…In silico dissection of crotalicidin (Ctn), a cathelicidin from a South American pit viper, yielded fragments Ctn[1–14] and Ctn[15–34], which were tested to…”
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The C-Terminus of Panusin, a Lobster β-Defensin, Is Crucial for Optimal Antimicrobial Activity and Serum Stability by Bello-Madruga, Roberto, Valle, Javier, Jiménez, M Ángeles, Torrent, Marc, Montero-Alejo, Vivian, Andreu, David

“…β-defensins are one of the most abundant and studied families of antimicrobial peptides (AMPs). Because of their selective toxicity to bacterial membranes and…”
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A CON-based NMR assignment strategy for pro-rich intrinsically disordered proteins with low signal dispersion: the C-terminal domain of histone H1.0 as a case study by Chaves-Arquero, Belén, Pantoja-Uceda, David, Roque, Alicia, Ponte, Inmaculada, Suau, Pedro, Jiménez, M. Angeles

“…The C-terminal domain of histone H1.0 (C-H1.0) is involved in DNA binding and is a main determinant of the chromatin condensing properties of histone H1.0…”
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Design and NMR conformational study of a β‐sheet peptide based on Betanova and WW domains by Fernández‐Escamilla, Ana M., Ventura, Salvador, Serrano, Luis, Jiménez, M. Angeles

“…A good approach to test our current knowledge on formation of protein β‐sheets is de novo protein design. To obtain a three‐stranded β‐sheet mini‐protein, we…”
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Comparison of Two Commercially Available Gamma Interferon Blood Tests for Immunodiagnosis of Tuberculosis by Domínguez, Jose, Ruiz-Manzano, Juan, De Souza-Galvão, Malú, Latorre, Irene, Milà, Celia, Blanco, Silvia, Jiménez, M. Ángeles, Prat, Cristina, Lacoma, Alicia, Altet, Neus, Ausina, Vicente

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Roles of Amphipathicity and Hydrophobicity in the Micelle‐Driven Structural Switch of a 14‐mer Peptide Core from a Choline‐Binding Repeat by Zamora‐Carreras, Héctor, Maestro, Beatriz, Strandberg, Erik, Ulrich, Anne S., Sanz, Jesús M., Jiménez, M. Ángeles

“…Choline‐binding repeats (CBRs) are ubiquitous sequences with a β‐hairpin core that are found in the surface proteins of several microorganisms such as S…”
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The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region by Apellániz, Beatriz, Rujas, Edurne, Serrano, Soraya, Morante, Koldo, Tsumoto, Kouhei, Caaveiro, Jose M.M., Jiménez, M. Ángeles, Nieva, José L.

“…The membrane-proximal external region (MPER) C-terminal segment and the transmembrane domain (TMD) of gp41 are involved in HIV-1 envelope glycoprotein-mediated…”
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Design of monomeric water-soluble β-hairpin and β-sheet peptides by Jiménez, M Angeles

“…Since the first report in 1993 (JACS 115, 5887-5888) of a peptide able to form a monomeric β-hairpin structure in aqueous solution, the design of peptides…”
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