Search Results - "Jim, Swoger"
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1
The role of spatially controlled cell proliferation in limb bud morphogenesis
Published in PLoS biology (01-07-2010)“…Although the vertebrate limb bud has been studied for decades as a model system for spatial pattern formation and cell specification, the cellular basis of its…”
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2
Defined chromosome structure in the genome-reduced bacterium Mycoplasma pneumoniae
Published in Nature communications (08-03-2017)“…DNA-binding proteins are central regulators of chromosome organization; however, in genome-reduced bacteria their diversity is largely diminished. Whether the…”
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3
Optical sectioning deep inside live embryos by selective plane illumination microscopy
Published in Science (American Association for the Advancement of Science) (13-08-2004)“…Large, living biological specimens present challenges to existing optical imaging techniques because of their absorptive and scattering properties. We…”
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4
OPTiSPIM: integrating optical projection tomography in light sheet microscopy extends specimen characterization to nonfluorescent contrasts
Published in Optics letters (15-02-2014)“…Mesoscopic 3D imaging has become a widely used optical imaging technique to visualize intact biological specimens. Selective plane illumination microscopy…”
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5
Antigen Availability and DOCK2-Driven Motility Govern CD4 + T Cell Interactions with Dendritic Cells In Vivo
Published in The Journal of immunology (1950) (15-07-2017)“…Parenchymal migration of naive CD4 T cells in lymph nodes (LNs) is mediated by the Rac activator DOCK2 and PI3Kγ and is widely assumed to facilitate efficient…”
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6
Light sheet fluorescence microscopy for in situ cell interaction analysis in mouse lymph nodes
Published in Journal of immunological methods (01-04-2016)“…Reactive lymph nodes (LNs) are sites where pMHC-loaded dendritic cells (DCs) interact with rare cognate T cells, leading to their clonal expansion. While DC…”
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7
Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis
Published in eLife (20-09-2018)“…The earliest developmental origins of dysmorphologies are poorly understood in many congenital diseases. They often remain elusive because the first signs of…”
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8
Naive B-cell trafficking is shaped by local chemokine availability and LFA-1–independent stromal interactions
Published in Blood (16-05-2013)“…It is not known how naive B cells compute divergent chemoattractant signals of the T-cell area and B-cell follicles during in vivo migration. Here, we used…”
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9
From Mouse to Man and Back: Closing the Correlation Gap between Imaging and Histopathology for Lung Diseases
Published in Diagnostics (Basel) (26-08-2020)“…Lung diseases such as fibrosis, asthma, cystic fibrosis, infection and cancer are life-threatening conditions that slowly deteriorate quality of life and for…”
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10
Born With Bristles: New Insights on the Kölliker’s Organs of Octopus Skin
Published in Frontiers in Marine Science (10-05-2021)“…The entire skin surface of octopus embryos, hatchlings and juveniles bears scattered tufts of tiny chitinous setae within small pockets, from which they can be…”
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11
4D retrospective lineage tracing using SPIM for zebrafish organogenesis studies
Published in Journal of biophotonics (01-01-2011)“…A study demonstrating an imaging framework that permits the determination of cell lineages during organogenesis of the posterior lateral line in zebrafish is…”
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12
Intravital imaging of hair-cell development and regeneration in the zebrafish
Published in Frontiers in neuroanatomy (2013)“…Direct videomicroscopic visualization of organ formation and regeneration in toto is a powerful strategy to study cellular processes that often cannot be…”
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13
Decrease in Cell Volume Generates Contractile Forces Driving Dorsal Closure
Published in Developmental cell (08-06-2015)“…Biological tissues must generate forces to shape organs and achieve proper development. Such forces often result from the contraction of an apical acto-myosin…”
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14
Ontogenetic and evolutionary trends on cephalopod digestive systems
Published in Reviews in fish biology and fisheries (11-11-2024)“…Meropelagic octopuses hatch as planktonic paralarvae, being the subject of progressive morphological and behavioural changes ending with settlement on the…”
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15
pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion
Published in The Journal of experimental medicine (14-11-2016)“…During adaptive immune responses, CD8 T cells with low TCR affinities are released early into the circulation before high-affinity clones become dominant at…”
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16
Maximizing content across scales: Moving multimodal microscopy and mesoscopy toward molecular imaging
Published in Current opinion in chemical biology (01-08-2021)“…Molecular imaging aims to depict the molecules in living patients. However, because this aim is still far beyond reach, patchworks of different solutions need…”
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REMBI: Recommended Metadata for Biological Images—enabling reuse of microscopy data in biology
Published in Nature methods (01-12-2021)“…Bioimaging data have significant potential for reuse, but unlocking this potential requires systematic archiving of data and metadata in public databases. We…”
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18
Multi-view image fusion improves resolution in three-dimensional microscopy
Published in Optics express (25-06-2007)“…A non-blind, shift-invariant image processing technique that fuses multi-view three-dimensional image data sets into a single, high quality three-dimensional…”
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High-resolution three-dimensional imaging of large specimens with light sheet-based microscopy
Published in Nature methods (01-04-2007)“…We report that single (or selective) plane illumination microscopy (SPIM), combined with a new deconvolution algorithm, provides a three-dimensional spatial…”
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20
Assessing Gene Expression Patterns in Mouse Models to Test Hypotheses About Human Head Evolution
Published in The FASEB journal (01-05-2021)“…Continuous fossil discoveries and recent analysis of genomic data are revealing that anatomically modern traits evolved following a complex evolutionary path…”
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