Search Results - "Jikihara, Sae"
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Dioxotriazine derivatives as a new class of P2X3 receptor antagonists: Identification of a lead and initial SAR studies
Published in Bioorganic & medicinal chemistry letters (01-04-2021)“…[Display omitted] P2X3 receptor is an ATP-gated ion channel, mainly localized on peripheral sensory neurons. Currently, several clinical trials are being…”
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Journal Article -
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Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds
Published in Bioorganic & medicinal chemistry letters (01-03-2019)“…[Display omitted] Some P2X3 receptor antagonists have been developed as new therapeutic drugs for pain. We discovered a novel chemotype of P2X3 receptor…”
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Journal Article -
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Dioxotriazine derivatives as a new class of P2X 3 receptor antagonists: Identification of a lead and initial SAR studies
Published in Bioorganic & medicinal chemistry letters (01-04-2021)“…P2X receptor is an ATP-gated ion channel, mainly localized on peripheral sensory neurons. Currently, several clinical trials are being conducted with P2X…”
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Journal Article