Search Results - "Jiemy, William F."

Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis by Esen, Idil, Jiemy, William F, van Sleen, Yannick, Bijzet, Johan, de Jong, Daniel M, Nienhuis, Pieter H, Slart, Riemer H J A, Heeringa, Peter, Boots, Annemieke M H, Brouwer, Elisabeth

“…Abstract Objectives GCA is a large vessel vasculitis in which metabolically active immune cells play an important role. GCA diagnosis is based on CRP/ESR and…”
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CD163 and CD206 expression define distinct macrophage subsets involved in active ANCA-associated glomerulonephritis by Aendekerk, Joop P., Jiemy, William F., Raveling-Eelsing, Elisabeth, Bijnens, Nele, Abdul-Hamid, Myrurgia A., Strating, Inge M., Dekkema, Gerjan J., Sanders, Jan-Stephan F., Stegeman, Coen A., Damoiseaux, Jan G.M.C., Little, Mark A., Heeringa, Peter, van Paassen, Pieter

“…Macrophages are key players in the immunopathology of anti-neutrophil cytoplasmic antibody (ANCA) mediated-vasculitis (AAV) with glomerulonephritis (ANCA GN)…”
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Evidence for increased interferon type I activity in CD8+ T cells in giant cell arteritis patients by van Nieuwland, Marieke, Esen, Idil, Reitsema, Rosanne D, Abdulahad, Wayel H, van Sleen, Yannick, Jiemy, William F, Sandovici, Maria, Brouwer, Elisabeth, van Bon, Lenny

“…Giant cell arteritis (GCA) is a vasculitis of the medium- and large-sized arteries. Interferon type I (IFN-I) is increasingly recognized as a key player in…”
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Contribution of pathogenic T helper 1 and 17 cells to bursitis and tenosynovitis in polymyalgia rheumatica by Reitsema, Rosanne D, Jiemy, William F, Wekema, Lieske, Boots, Annemieke M H, Heeringa, Peter, Huitema, Minke G, Abdulahad, Wayel H, van Sleen, Yannick, Sandovici, Maria, Roozendaal, Caroline, Diepstra, Arjan, Kwee, Thomas, Dasgupta, Bhaskar, Brouwer, Elisabeth, van der Geest, Kornelis S M

“…Although polymyalgia rheumatica (PMR) is a very common rheumatic inflammatory disease, current insight into the pathobiology of PMR is limited and largely…”
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Novel PET Imaging of Inflammatory Targets and Cells for the Diagnosis and Monitoring of Giant Cell Arteritis and Polymyalgia Rheumatica by van der Geest, Kornelis S. M., Sandovici, Maria, Nienhuis, Pieter H., Slart, Riemer H. J. A., Heeringa, Peter, Brouwer, Elisabeth, Jiemy, William F.

“…Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated inflammatory diseases affecting patients above 50 years of age. Patients with…”
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Distinct macrophage phenotypes skewed by local granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) are associated with tissue destruction and intimal hyperplasia in giant cell arteritis by Jiemy, William F, Sleen, Yannick, Geest, Kornelis SM, Berge, Hilde A, Abdulahad, Wayel H, Sandovici, Maria, Boots, Annemieke MH, Heeringa, Peter, Brouwer, Elisabeth

“…Objective To determine the presence and spatial distribution of different macrophage phenotypes, governed by granulocyte macrophage colony‐stimulating factor…”
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Evaluation of Hydra HALT-1 as a toxin moiety for recombinant immunotoxin by Jiemy, William F, Hiew, Lih Fhung, Sha, Hong Xi, In, Lionel L. A, Hwang, Jung Shan

“…Immunotoxin is a hybrid protein consisting of a toxin moiety that is linked to a targeting moiety for the purpose of specific elimination of target cells…”
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A Distinct Macrophage Subset Mediating Tissue Destruction and Neovascularization in Giant Cell Arteritis: Implication of the YKL‐40/Interleukin‐13 Receptor α2 Axis by Sleen, Yannick, Jiemy, William F., Pringle, Sarah, Geest, Kornelis S. M., Abdulahad, Wayel H., Sandovici, Maria, Brouwer, Elisabeth, Heeringa, Peter, Boots, Annemieke M. H.

“…Objective Macrophages mediate inflammation, angiogenesis, and tissue destruction in giant cell arteritis (GCA). Serum levels of the macrophage‐associated…”
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Expression of interleukin-6 in synovial tissue of patients with polymyalgia rheumatica by Jiemy, William F, Zhang, Anqi, Boots, Annemieke M H, Heeringa, Peter, Sandovici, Maria, Diepstra, Arjan, Hein, Sandra, Dasgupta, Bhaskar, Brouwer, Elisabeth, van der Geest, Kornelis Sm

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The immune pathology of bursitis in rheumatic inflammatory diseases, degenerative conditions and mechanical stress: A systematic review by Zhang, Anqi, Brouwer, Elisabeth, Sandovici, Maria, Diepstra, Arjan, Jiemy, William F., van der Geest, Kornelis S.M.

“…To summarize current insights on the immune pathology of bursitis caused by rheumatic inflammatory diseases, degenerative conditions, or mechanical stress and…”
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Indication of Activated Senescence Pathways in the Temporal Arteries of Patients With Giant Cell Arteritis by Jiemy, William F, van Sleen, Yannick, Graver, Jacoba C, Pringle, Sarah, Brouwer, Elisabeth, van der Geest, K S M, Cornec, Divi, Boots, Annemieke M H, Sandovici, Maria

“…Giant cell arteritis (GCA) affects almost exclusively individuals above 50 years old, suggesting a role of aging-related changes such as cellular senescence in…”
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Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD8+ T cells in giant cell arteritis by Reitsema, Rosanne D, van der Geest, Kornelis S M, Sandovici, Maria, Jiemy, William F, Graver, Jacoba C, Abdulahad, Wayel H, Boots, Annemieke M H, Heeringa, Peter, Brouwer, Elisabeth

“…Evidence from temporal artery tissue and blood suggests involvement of CD8+ T cells in the pathogenesis of GCA, but their exact role is poorly understood…”
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Altered Plasma Levels and Tissue Expression of Fibroblast Activation Protein Alpha in Giant Cell Arteritis by Xu, Shuang, Jiemy, William F., Boots, Annemieke M. H., Arends, Suzanne, Sleen, Yannick, Nienhuis, Pieter H., Geest, Kornelis S. M., Heeringa, Peter, Brouwer, Elisabeth, Sandovici, Maria

“…Objective Giant cell arteritis (GCA) is characterized by granulomatous inflammation of the medium‐ and large‐sized arteries accompanied by remodeling of the…”
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Current evidence on the role of fibroblasts in large-vessel vasculitides: From pathogenesis to therapeutics by Xu, Shuang, Jiemy, William F., Brouwer, Elisabeth, Burgess, Janette K., Heeringa, Peter, van der Geest, Kornelis S.M., Alba-Rovira, Roser, Corbera-Bellalta, Marc, Boots, Annemieke H., Cid, Maria C., Sandovici, Maria

“…Large-vessel vasculitides (LVV) comprise a group of chronic inflammatory diseases of the aorta and its major branches. The most common forms of LVV are giant…”
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Cytokine producing B-cells and their capability to polarize macrophages in giant cell arteritis by Graver, Jacoba C., Jiemy, William F., Altulea, Dania H.A., van Sleen, Yannick, Xu, Shuang, van der Geest, Kornelis S.M., Verstappen, Gwenny M.P.J., Heeringa, Peter, Abdulahad, Wayel H., Brouwer, Elisabeth, Boots, Annemieke M.H., Sandovici, Maria

“…The lack of disease-specific autoantibodies in giant cell arteritis (GCA) suggests an alternative role for B-cells readily detected in the inflamed arteries…”
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Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters by Stempels, Femmy C, Jiang, Muwei, Warner, Harry M, Moser, Magda-Lena, Janssens, Maaike H, Maassen, Sjors, Nelen, Iris H, de Boer, Rinse, Jiemy, William F, Knight, David, Selley, Julian, O'Cualain, Ronan, Baranov, Maksim V, Burgers, Thomas C Q, Sansevrino, Roberto, Milovanovic, Dragomir, Heeringa, Peter, Jones, Matthew C, Vlijm, Rifka, Ter Beest, Martin, van den Bogaart, Geert

“…Endosomal Sorting Complex Required for Transport (ESCRT) proteins can be transiently recruited to the plasma membrane for membrane repair and formation of…”
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Comment on: Plasma Pyruvate Kinase M2 as a marker of vascular inflammation in giant cell arteritis: reply by Esen, Idil, Jiemy, William F, van Sleen, Yannick, Reitsema, Rosanne D, Bijzet, Johan, de Jong, Daniel M, Nienhuis, Pieter H, Slart, Riemer H J A, Heeringa, Peter, Boots, Annemieke M H, Brouwer, Elisabeth

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Positron Emission Tomography Imaging in Vasculitis by van der Geest, Kornelis S.M., Slijkhuis, Berend G.C., Tomelleri, Alessandro, Gheysens, Olivier, Jiemy, William F., Piccolo, Costanza, Nienhuis, Pieter, Sandovici, Maria, Brouwer, Elisabeth, Glaudemans, Andor W.J.M., Mulder, Douwe J., Slart, Riemer H.J.A.

“…Systemic vasculitides comprise a group of autoimmune diseases affecting blood vessels. [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed…”
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Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment by Esen, Idil, Jiemy, William F., van Sleen, Yannick, van der Geest, Kornelis S.M., Sandovici, Maria, Heeringa, Peter, Boots, Annemieke M. H., Brouwer, Elisabeth

“…Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that affects adults above 50 years of age. In GCA, circulating monocytes are recruited to…”
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Serum Soluble CD206 Complements Urinary Soluble CD163 in Detecting Active ANCA-Associated Glomerulonephritis: PO1417 by Aendekerk, Joop, Jiemy, William F., Strating, Inge M., Dekkema, Gerjan J., Sanders, Jan-Stephan, Stegeman, Coen A., Little, Mark A., Heeringa, Peter, van Paassen, Pieter

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