Search Results - "Jiao, Xiaozhen"
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1
Expanding the Range of CRISPR/Cas9 Genome Editing in Rice
Published in Molecular plant (06-06-2016)“…Dear Editor The CRISPR/Cas9 system has emerged as a versatile molecular tool for genome editing in various organisms, including plants. In this system, the…”
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2
Rapid generation of genetic diversity by multiplex CRISPR/Cas9 genome editing in rice
Published in Science China. Life sciences (01-05-2017)“…The clustered regularly interspaced short palindromic repeats(CRISPR)-associated endonuclease 9(CRISPR/Cas9) system has emerged as a promising technology for…”
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3
High-resolution mapping and breeding application of a novel brown planthopper resistance gene derived from wild rice (Oryza. rufipogon Griff)
Published in Rice (New York, N.Y.) (04-06-2019)“…Background The brown planthopper ( Nilaparvata lugens Stål; BPH), one of the most destructive pests of rice, has proven to be a substantial threat, conferring…”
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4
FED: a web tool for foreign element detection of genome-edited organism
Published in Science China. Life sciences (2021)Get full text
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5
Development of Specific Molecular and Phenotypic Marker-Based Haploid Inducers in Rice
Published in Agronomy (Basel) (01-06-2023)“…Doubled haploid (DH) technology is an efficient strategy for producing completely homozygous lines for breeding programs. Mutations in the MATRILINEAL (MTL)…”
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6
Discovery of Novel N-Substituted Prolinamido Indazoles as Potent Rho Kinase Inhibitors and Vasorelaxation Agents
Published in Molecules (Basel, Switzerland) (19-10-2017)“…Inhibitors of Rho kinase (ROCK) have potential therapeutic applicability in a wide range of diseases, such as hypertension, stroke, asthma and glaucoma. In a…”
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7
The Protective Effect of DL0805 Derivatives on Pulmonary Artery Cells and the Underlying Mechanisms Study
Published in Current vascular pharmacology (01-01-2017)“…Pulmonary hypertension (PH) is a severe disease characterized by a progressive increase in pulmonary vascular resistance, initially due to abnormal pulmonary…”
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8
Development and application of EST-SSR to evaluate the genetic diversity of Southeast Asian rice planthoppers
Published in Journal of Asia-Pacific entomology (01-09-2016)“…A total of 320 ESTs (Expressed Sequence Tags, 12.8%) of rice planthoppers were identified to carry SSR (Simple Sequence Repeat) motifs from 2491 ESTs…”
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9
The vasorelaxant mechanisms of a Rho kinase inhibitor DL0805 in rat thoracic aorta
Published in Molecules (Basel, Switzerland) (18-05-2012)“…Rho-kinase has been suggested as a potential therapeutic target in the treatment of cardiovascular diseases. The Rho-kinase signaling pathway is substantially…”
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10
Short and straightforward total synthesis of Ammosamide B
Published in Tetrahedron letters (15-09-2010)“…A simple and five steps total synthesis of Ammosamide B has been developed. The tricyclic pyrroloquinoline in Ammosamides was constructed in one step based on…”
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11
Hi-TOM: a platform for high-throughput tracking of mutations induced by CRISPR/Cas systems
Published in Science China. Life sciences (2019)“…The CRISPR/Cas system has been extensively applied to make precise genetic modifications in various organisms. Despite its importance and widespread use,…”
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12
Total Synthesis of (−)-Levesquamide
Published in Journal of organic chemistry (17-03-2023)“…The total synthesis of levesquamide, a natural product with an unprecedented pentasubstituted pyridine-isothiazolinone skeleton, has been accomplished from…”
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13
Knockout of OsHMA3 in an indica rice increases cadmium sensitivity and inhibits plant growth
Published in Plant growth regulation (01-07-2024)“…Cadmium (Cd) is a heavy metal that poses harm to both plants and humans. OsHMA3, a member of the heavy metal ATPase (HMA) family, plays a crucial role in…”
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14
Total Synthesis of the Proposed Structure of Characellide B
Published in Organic letters (07-05-2021)“…We achieved the total synthesis of the proposed structure of characellide B, a novel lipoglycotripeptide. Comparison of the data for the synthetic compound…”
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15
An approach to (±)-Lingzhiol
Published in Organic letters (15-04-2016)“…(±)-Lingzhiol has been synthesized from commercially available 5,8-dimethoxytetralone in seven steps with an overall yield of 10.3% via an unprecedented…”
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16
Asymmetric total synthesis of (+)-isocryptotanshinone and formal synthesis of (−)-cryptotanshinone
Published in Tetrahedron (26-07-2019)“…The first asymmetric total synthesis of (+)-isocryptotanshinone was achieved in 12 linear steps with 12% overall yield from commercially available…”
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17
New bysspectin A derivatives as potent inhibitors of human carboxylesterase 2A
Published in European journal of medicinal chemistry (05-11-2023)“…Human carboxylesterase 2A (hCES2A), the most abundant carboxylesterase in the human gut, plays a crucial role in the metabolic clearance and activation of…”
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18
Total synthesis of bysspectin A
Published in Tetrahedron (07-06-2019)“…Bysspectin A (1), an unusual polyketide-derived octaketide dimer, has highly selective inhibitory activities against human carboxylesterase 2 (hCE2) with an…”
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19
Design, synthesis and biological evaluation of substituted (+)-SG-1 derivatives as novel anti-HIV agents
Published in Bioorganic & medicinal chemistry letters (01-06-2018)“…[Display omitted] •A series of potent HIV-1 reverse transcriptase inhibitors were synthesized.•Compound 4b showed potent inhibitory activity against HIV-1(IC50…”
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(+)-Isocryptotanshinone derivatives and its simplified analogs as STAT3 signaling pathway inhibitors
Published in Bioorganic chemistry (01-10-2022)“…[Display omitted] •STAT3 signaling pathways and tumors are closely related.•A variety of ICTS derivatives and simplified analogs have designed and…”
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