Search Results - "Jiao, Shiping"

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression by Jiao, Shiping, Xia, Weiya, Yamaguchi, Hirohito, Wei, Yongkun, Chen, Mei-Kuang, Hsu, Jung-Mao, Hsu, Jennifer L, Yu, Wen-Hsuan, Du, Yi, Lee, Heng-Huan, Li, Chia-Wei, Chou, Chao-Kai, Lim, Seung-Oe, Chang, Shih-Shin, Litton, Jennifer, Arun, Banu, Hortobagyi, Gabriel N, Hung, Mien-Chie

“…To explore whether a cross-talk exists between PARP inhibition and PD-L1/PD-1 immune checkpoint axis, and determine whether blockade of PD-L1/PD-1 potentiates…”
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Unraveling the spatial organization and development of human thymocytes through integration of spatial transcriptomics and single-cell multi-omics profiling by Li, Yanchuan, Li, Huamei, Peng, Cheng, Meng, Ge, Lu, Yijun, Liu, Honglin, Cui, Li, Zhou, Huan, Xu, Zhu, Sun, Lingyun, Liu, Lihong, Xiong, Qing, Sun, Beicheng, Jiao, Shiping

“…The structural components of the thymus are essential for guiding T cell development, but a thorough spatial view is still absent. Here we develop the TSO-his…”
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Comprehensive description of the current breast cancer microenvironment advancements via single-cell analysis by Yan, Xueqi, Xie, Yinghong, Yang, Fan, Hua, Yijia, Zeng, Tianyu, Sun, Chunxiao, Yang, Mengzhu, Huang, Xiang, Wu, Hao, Fu, Ziyi, Li, Wei, Jiao, Shiping, Yin, Yongmei

“…Breast cancer is a heterogeneous disease with a complex microenvironment consisting of tumor cells, immune cells, fibroblasts and vascular cells. These…”
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Efficacy, safety, and immunogenicity of SARS-CoV-2 mRNA vaccine (Omicron BA.5) LVRNA012: a randomized, double-blind, placebo-controlled phase 3 trial by Zhou, Huan, Zheng, Hui, Peng, Yucai, Su, Yue, Yu, Xuya, Wang, Weixiao, Li, Simin, Ding, Yuzhou, Jiao, Shiping, Wang, Ying, Zhu, Xingyu, Luo, Liping, Dong, Ziyong, Liu, Lu, Zhang, Fan, Wu, Qiang, Li, Jingxin, Zhu, Fengcai

“…We aimed to evaluate the efficacy, safety, and immunogenicity of a SARS-CoV-2 mRNA vaccine (Omicron BA.5) LVRNA012 given as the booster in immunized but…”
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Intratumor expanded T cell clones can be non-sentinel lymph node derived in breast cancer revealed by single-cell immune profiling by Jiao, Shiping, Xiong, Qing, Yan, Meisi, Zhan, Xiaolu, Yang, Zhenhuang, Peng, Cheng, Sun, Beicheng, Pang, Da, Liu, Tong

“…BackgroundSentinel lymph nodes (LNs) are regarded as key immune surveillance sites in cancer wherein mature dendritic cells present tumor-derived antigens to…”
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Characteristics of SARS-CoV-2-specific cytotoxic T cells revealed by single-cell immune profiling of longitudinal COVID-19 blood samples by Xiong, Qing, Peng, Cheng, Yan, Xiaomin, Yan, Xueqi, Chen, Lin, Sun, Beicheng, Jiao, Shiping

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BikDDA, a mutant of Bik with longer half-life expression protein, can be a novel therapeutic gene for triple-negative breast cancer by Jiao, Shiping, Wu, Minqing, Ye, Feng, Tang, Hailin, Xie, Xinhua, Xie, Xiaoming

“…Our previous studies showed that BikDD, a constitutively active mutant form of Bik, exhibited powerful antitumor effects in preclinical pancreatic, lung and…”
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Nrdp1 expression to predict clinical outcome and efficacy of adjuvant anthracyclines-based chemotherapy in breast cancer: A retrospective study by Jiao, Shiping, Liu, Wenjie, Wu, Minqing, Peng, Cheng, Tang, Hailin, Xie, Xiaoming

“…Existing reports showed loss of Nrdp1, an E3 ubiquitin ligase, promoted breast cancer malignancy because of failure to deregulate ErbB3. However, the…”
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Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy by Jiao, Shiping, Subudhi, Sumit K., Aparicio, Ana, Ge, Zhongqi, Guan, Baoxiang, Miura, Yuji, Sharma, Padmanee

“…Immune checkpoint therapy (ICT) shows encouraging results in a subset of patients with metastatic castration-resistant prostate cancer (mCRPC) but still…”
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EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer by Yamaguchi, H, Du, Y, Nakai, K, Ding, M, Chang, S-S, Hsu, J L, Yao, J, Wei, Y, Nie, L, Jiao, S, Chang, W-C, Chen, C-H, Yu, Y, Hortobagyi, G N, Hung, M-C

“…Inhibitors against poly (ADP-ribose) polymerase (PARP) are promising targeted agents currently used to treat BRCA -mutant ovarian cancer and are in clinical…”
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Abstract 6665: A spatiotemporal cell atlas of human gastric malignancy reveals mechanisms underlying metastasis and immunotherapy response by Luo, Yikai, Kang, Muxing, Liu, Wei, Jiao, Shiping, Wang, Lie, Chen, Jian, Liang, Han

“…Abstract Cellular heterogeneity in the tumor immune microenvironment (TIME) of gastric cancer (GC) is progressively molded in pre- and early-malignant lesions…”
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BikDDA, a Mutant of Bik with Longer Half-Life Expression Protein, Can Be a Novel Therapeutic Gene for Triple-Negative Breast Cancer: e92172 by Jiao, Shiping, Wu, Minqing, Ye, Feng, Tang, Hailin, Xie, Xinhua, Xie, Xiaoming

“…Our previous studies showed that BikDD, a constitutively active mutant form of Bik, exhibited powerful antitumor effects in preclinical pancreatic, lung and…”
Get full text