Search Results - "Jiao, Shimeng"
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Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives
Published in Frontiers in pharmacology (12-10-2022)“…Treatment-resistant schizophrenia (TRS) often results in severe disability and functional impairment. Currently, the diagnosis of TRS is largely exclusionary…”
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Pre-treatment risk predictors of valproic acid-induced dyslipidemia in pediatric patients with epilepsy
Published in Frontiers in pharmacology (02-04-2024)“…Valproic acid (VPA) stands as one of the most frequently prescribed medications in children with newly diagnosed epilepsy. Despite its infrequent adverse…”
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B-GOS alleviates olanzapine-induced lipid disturbances in mice by enriching Akkermansia and upregulation of PGRMC1-Wnt signaling
Published in Food and chemical toxicology (01-03-2024)“…Although olanzapine (OLZ) remains one of the most efficacious antipsychotic medications for the treatment of schizophrenia, there are significant tolerability…”
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Differential impact of intermittent versus continuous treatment with clozapine on fatty acid metabolism in the brain of an MK-801-induced mouse model of schizophrenia
Published in Progress in neuro-psychopharmacology & biological psychiatry (13-07-2024)“…Continuous antipsychotic treatment is often recommended to prevent relapse in schizophrenia. However, the efficacy of antipsychotic treatment appears to…”
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Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells
Published in Toxicology (Amsterdam) (01-06-2023)“…Clozapine is usually considered as the last resort for treatment-resistant schizophrenia (TRS). However, it shows limited efficacy in cognition improvement…”
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Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts
Published in European archives of psychiatry and clinical neuroscience (01-10-2022)“…Neurotransmitter metabolism plays a critical role in the pathophysiology of major depressive disorder (MDD). However, whether the neurotransmitter metabolism…”
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Long non-coding RNAs in schizophrenia: Genetic variations, treatment markers and potential targeted signaling pathways
Published in Schizophrenia research (01-10-2023)“…Schizophrenia (SZ), a complex and debilitating spectrum of psychiatric disorders, is now mainly attributed to multifactorial etiology that includes genetic and…”
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The Involvement of PGRMC1 Signaling in Cognitive Impairment Induced by Long-Term Clozapine Treatment in Rats
Published in Neuropsychobiology (01-12-2023)“…Progesterone receptor component 1 (PGRMC1) has been identified as a potential target in atypical antipsychotic drug-induced metabolic disturbances as well as…”
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Generation and Developmental Characteristics of Porcine Tetraploid Embryos and Tetraploid]diploid Chimeric Embryos
Published in Genomics, proteomics & bioinformatics (01-10-2013)“…The aim of this study was to optimize electrofusion conditions for generating porcine tet- raploid (4n) embryos and produce tetraploid/diploid (4n/2n) chimeric…”
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