Search Results - "Jianying, Liu"
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Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera
Published in Nature medicine (01-04-2021)“…We engineered three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viruses containing key spike mutations from the newly emerged United Kingdom…”
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Neutralizing Activity of BNT162b2-Elicited Serum
Published in The New England journal of medicine (15-04-2021)“…How well do serum samples obtained from persons injected with the BNT162b2 vaccine neutralize the P.1, B.1.1.7, and B.1.135 lineages of SARS-CoV-2, first…”
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The N501Y spike substitution enhances SARS-CoV-2 infection and transmission
Published in Nature (London) (10-02-2022)“…The B.1.1.7 variant (also known as Alpha) of SARS-CoV-2, the cause of the COVID-19 pandemic, emerged in the UK in the summer of 2020. The prevalence of this…”
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BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants
Published in Nature (London) (12-08-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuing to evolve around the world, generating new variants that are of concern on the basis…”
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Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes
Published in Nature (London) (25-05-2017)“…A mutation that increases the secretion of Zika virus non-structural protein 1 (NS1) in infected hosts enhances the ability of the virus to infect its mosquito…”
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A receptor‐like protein from Nicotiana benthamiana mediates VmE02 PAMP‐triggered immunity
Published in The New phytologist (01-02-2021)“…Summary Plants use their innate immune system to defend against phytopathogens. As a part of this, pattern triggered‐immunity is activated via pattern…”
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UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation
Published in BMC cancer (18-04-2024)“…This study aims to investigate the role and mechanism of tubiquitin-conjugating enzyme E2 C (UBE2C) in acute myeloid leukemia (AML). Initially, UBE2C…”
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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Published in Nature communications (15-10-2020)“…A high-throughput platform would greatly facilitate coronavirus disease 2019 (COVID-19) serological testing and antiviral screening. Here we present a…”
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A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions
Published in Nature communications (27-07-2022)“…We report a live-attenuated SARS-CoV-2 vaccine candidate with (i) re-engineered viral transcription regulator sequences and (ii) deleted open-reading-frames…”
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Integrated physiological and metabolomic analyses reveal changes during the natural senescence of Quercus mongolica leaves
Published in PloS one (23-08-2023)“…Quercus mongolica is a common landscape, afforestation, and construction timber species in northern China with high ecological, economic, and ornamental value…”
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Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention
Published in PLoS pathogens (01-02-2014)“…C-type lectins are a family of proteins with carbohydrate-binding activity. Several C-type lectins in mammals or arthropods are employed as receptors or…”
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Reversible encephalitis-like episodes in fragile X-associated tremor/ataxia syndrome: a case report
Published in BMC neurology (07-05-2024)“…Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder caused by CGG repeat expansion of FMR1 gene. Both FXTAS and neuronal…”
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Aedes mosquitoes acquire and transmit Zika virus by breeding in contaminated aquatic environments
Published in Nature communications (22-03-2019)“…Zika virus (ZIKV) is a mosquito-borne flavivirus that predominantly circulates between humans and Aedes mosquitoes. Clinical studies have shown that Zika…”
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A deep learning algorithm for detection of oral cavity squamous cell carcinoma from photographic images: A retrospective study
Published in EClinicalMedicine (01-10-2020)“…The overall prognosis of oral cancer remains poor because over half of patients are diagnosed at advanced-stages. Previously reported screening and earlier…”
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Vaccines and immunization strategies for dengue prevention
Published in Emerging microbes & infections (20-07-2016)“…Dengue is currently the most significant arboviral disease afflicting tropical and sub-tropical countries worldwide. Dengue vaccines, such as the multivalent…”
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Role of mutational reversions and fitness restoration in Zika virus spread to the Americas
Published in Nature communications (26-01-2021)“…Zika virus (ZIKV) emerged from obscurity in 2013 to spread from Asia to the South Pacific and the Americas, where millions of people were infected, accompanied…”
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Nep1-like Proteins from Valsa mali Differentially Regulate Pathogen Virulence and Response to Abiotic Stresses
Published in Journal of fungi (Basel) (04-10-2021)“…Necrosis and ethylene-inducing peptide 1(Nep1)-like protein (NLP) is well known for its cytotoxicity and immunogenicity on dicotyledonous, and it has attracted…”
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The roles of direct recognition by animal lectins in antiviral immunity and viral pathogenesis
Published in Molecules (29-01-2015)“…Lectins are a group of proteins with carbohydrate recognition activity. Lectins are categorized into many families based on their different cellular locations…”
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SARS-CoV-2 variants and vaccination
Published in Zoonoses (Burlington, Mass.) (01-01-2022)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused global destruction since its emergence in late 2019. Over the past two years, the…”
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Immunogenicity and efficacy of vaccine boosters against SARS-CoV-2 Omicron subvariant BA.5 in male Syrian hamsters
Published in Nature communications (17-07-2023)“…The SARS-CoV-2 Omicron subvariant BA.5 rapidly spread worldwide and replaced BA.1/BA.2 in many countries, becoming globally dominant. BA.5 has unique amino…”
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