Search Results - "Jianye PENG"
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The Role of Cold Inducible RNA-Binding Protein in Cardiac Physiology and Diseases
Published in Frontiers in pharmacology (24-02-2021)“…Cold-inducible RNA-binding protein (CIRP) is an intracellular stress-response protein that can respond to various stress conditions by changing its expression…”
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Role of CaMKII in free fatty acid/hyperlipidemia-induced cardiac remodeling both in vitro and in vivo
Published in Journal of molecular and cellular cardiology (01-08-2017)“…The cellular mechanisms of obesity/hyperlipidemia-induced cardiac remodeling are many and not completely elucidated. Ca2+/calmodulin-dependent protein kinase…”
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Mediating effect of oxidative stress on blood pressure elevation in workers exposed to low concentrations of benzene, toluene, and xylene (BTX)
Published in Scientific reports (30-10-2024)“…To investigate the mediating effect of oxidative stress on the relationships between low-concentration benzene, toluene, and xylene (BTX) exposure and blood…”
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AAV9-Mediated Cardiac CNTF Overexpression Exacerbated Adverse Cardiac Remodeling in Streptozotocin-Induced Type 1 Diabetic Models
Published in Cardiovascular toxicology (2022)“…Ciliary neurotrophic factor (CNTF), which is a neural peptide, has been reported to confer cardioprotective effects. However, whether CNTF-based gene delivery…”
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The Mitochondrial-Derived Peptide MOTS-c Attenuates Oxidative Stress Injury and the Inflammatory Response of H9c2 Cells Through the Nrf2/ARE and NF-κB Pathways
Published in Cardiovascular engineering and technology (01-10-2022)“…Aim Oxidative stress and the inflammatory response contribute to the progression of cardiovascular disease. The present study aimed to investigate whether the…”
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Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats
Published in BMC cardiovascular disorders (27-03-2024)“…Downregulated expression of cold-inducible RNA binding protein (CIRP), a stress-response protein, has been demonstrated in the hearts of patients with heart…”
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Sarcolipin acts as a bridge between diabetes and heart failure
Published in ESC Heart Failure (01-12-2020)Get full text
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Loss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling
Published in Scientific reports (11-07-2017)“…Myeloid differentiation protein 1 (MD1) has been implicated in numerous pathophysiological processes, including immune regulation, obesity, insulin resistance,…”
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Regulator of G-protein signaling 5 protects cardiomyocytes against apoptosis during in vitro cardiac ischemia-reperfusion in mice by inhibiting both JNK1/2 and P38 signaling pathways
Published in Biochemical and biophysical research communications (29-04-2016)“…Ischemic heart disease is one of the most common diseases in modern society. Ischemic myocardium can be salvaged by vascular recanalization therapy, but its…”
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Crocin alleviates neurotoxicity induced by bupivacaine in SH-SY5Y cells with inhibition of PI3K/AKT signaling
Published in Genes & genomics (2024)“…Background Bupivacaine, a common local anesthetic, can cause neurotoxicity and permanent neurological disorders. Crocin has been widely reported as a potential…”
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The Akt pathway mediates the protective effects of myeloid differentiation protein 1 in pathological cardiac remodelling
Published in ESC Heart Failure (01-08-2021)“…Aims Myeloid differentiation protein 1 (MD1) was shown to ameliorate pressure overload‐induced cardiac hypertrophy and fibrosis by negatively regulating the…”
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Identification of differentially expressed circRNAs in cardiac ischemic reperfusion injury
Published in International journal of cardiology (15-05-2020)Get full text
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Cold‐inducible RNA‐binding protein (CIRP) in inflammatory diseases: Molecular insights of its associated signalling pathways
Published in Scandinavian journal of immunology (01-01-2021)“…Cold‐inducible RNA‐binding protein (CIRP) was previously identified as an intracellular stress‐response protein, which can respond to a variety of stress…”
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Mitochondrial derived peptide MOTS‐c prevents the development of heart failure under pressure overload conditions in mice
Published in Journal of cellular and molecular medicine (01-11-2022)“…MOTS‐c, a mitochondrial‐derived peptide (MDP), has been shown to have multiple biological activities such as antioxidation, anti‐inflammation, and…”
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Resveratrol protects against ox-LDL-induced endothelial dysfunction in atherosclerosis via depending on circ_0091822/miR-106b-5p-mediated upregulation of TLR4
Published in Immunopharmacology and immunotoxicology (02-11-2022)“…Atherosclerosis (AS) is the most common inducer of cardiovascular diseases, and resveratrol (RSV) has played a protective function in the endothelial injury of…”
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Interleukin‐5 alleviates cardiac remodelling via the STAT3 pathway in angiotensin II‐infused mice
Published in Journal of cellular and molecular medicine (01-07-2024)“…Interleukin‐5 (IL‐5) has been reported to be involved in cardiovascular diseases, such as atherosclerosis and cardiac injury. This study aimed to investigate…”
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Loss of MD1 Promotes Inflammatory and Apoptotic Atrial Remodelling in Diabetic Cardiomyopathy by Activating the TLR4/NF-κB Signalling Pathway
Published in Pharmacology (01-07-2023)“…Myeloid differentiation protein 1 (MD1), a negative regulator of toll-like receptor 4 (TLR4), is widely expressed in the heart. Recent studies have shown that…”
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The role of Cold‐Inducible RNA‐binding protein in respiratory diseases
Published in Journal of cellular and molecular medicine (01-02-2022)“…Cold‐inducible RNA‐binding protein (CIRP) is a stress‐response protein that is expressed in various types of cells and acts as an RNA chaperone, modifying the…”
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CTRP5 Attenuates Doxorubicin-Induced Cardiotoxicity Via Inhibiting TLR4/NLRP3 Signaling
Published in Cardiovascular drugs and therapy (31-05-2023)“…C1q/tumor necrosis factor-related protein 5 (CTRP5) has been reported to be a crucial regulator in cardiac ischemia/reperfusion (I/R) injury. Nevertheless, the…”
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