Search Results - "Jianjun Cheng"
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Nonporous silica nanoparticles for nanomedicine application
Published in Nano today (01-06-2013)“…•Controlled synthesis of size- and shape-specific silica nanomaterials.•Silica nanoparticles for drug, protein and gene delivery.•Silica nanoparticles for…”
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2
Dynamic urea bond for the design of reversible and self-healing polymers
Published in Nature communications (04-02-2014)“…Polymers bearing dynamic covalent bonds may exhibit dynamic properties, such as self-healing, shape memory and environmental adaptation. However, most dynamic…”
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3
Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation
Published in Advanced drug delivery reviews (01-03-2021)“…The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have sounded a piercing alarm for the need of new effective antimicrobial…”
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4
Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application
Published in Chemical Society reviews (30-10-2017)“…Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides (NCAs) are one of the most important biomaterials. The unique features of…”
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5
Alternatively activated macrophages; a double-edged sword in allergic asthma
Published in Journal of translational medicine (05-02-2020)“…Macrophages are heterogenous phagocytic cells with an important role in the innate immunity. They are, also, significant contributors in the adaptive immune…”
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6
A Hybrid Spectral Clustering and Deep Neural Network Ensemble Algorithm for Intrusion Detection in Sensor Networks
Published in Sensors (Basel, Switzerland) (13-10-2016)“…The development of intrusion detection systems (IDS) that are adapted to allow routers and network defence systems to detect malicious network traffic…”
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7
Preparation, characterization, and antioxidant activity of zein nanoparticles stabilized by whey protein nanofibrils
Published in International journal of biological macromolecules (15-01-2021)“…The application of natural biopolymers to develop colloidal carriers for delivering hydrophobic bioactive molecules has become one of the hottest topics in…”
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Synthesis and Biomedical Applications of Functional Poly(α-hydroxy acids) via Ring-Opening Polymerization of O‑Carboxyanhydrides
Published in Accounts of chemical research (21-07-2015)“…Poly(α-hydroxy acids) (PAHAs) are a class of biodegradable and biocompatible polymers that are widely used in numerous applications. One drawback of these…”
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9
Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy
Published in Nano letters (14-03-2018)“…Various delivery vectors have been integrated within biologically derived membrane systems to extend their residential time and reduce their…”
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10
Structure-based discovery of nonhallucinogenic psychedelic analogs
Published in Science (American Association for the Advancement of Science) (28-01-2022)“…Drugs that target the human serotonin 2A receptor (5-HT R) are used to treat neuropsychiatric diseases; however, many have hallucinogenic effects, hampering…”
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11
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure–Functional Selectivity Relationships (SFSRs) and Therapeutic Potential
Published in Journal of medicinal chemistry (21-11-2018)“…G protein-coupled receptors (GPCRs) signal through both G-protein-dependent and G-protein-independent pathways, and β-arrestin recruitment is the most…”
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12
N-Trimethylsilyl Amines for Controlled Ring-Opening Polymerization of Amino Acid N-Carboxyanhydrides and Facile End Group Functionalization of Polypeptides
Published in Journal of the American Chemical Society (24-09-2008)“…We report a new strategy that uses N-trimethylsilyl (N-TMS) amine to mediate controlled ring-opening polymerization of amino acid N-carboxyanhydrides (NCAs)…”
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13
Materials, Designs, and Operational Characteristics for Fully Biodegradable Primary Batteries
Published in Advanced materials (Weinheim) (18-06-2014)“…Biodegradable electronics represent an emerging class of technology with potential to provide advanced semiconductor functionality in temporary biomedical…”
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14
Ring-Opening Polymerization-Mediated Controlled Formulation of Polylactide−Drug Nanoparticles
Published in Journal of the American Chemical Society (08-04-2009)“…We report here a unique method for formulating doxorubicin−polylactide (Doxo-PLA) conjugate nanoparticles, known as nanoconjugates (NCs), through…”
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15
Effect of residence time on chemical and structural properties of hydrochar obtained by hydrothermal carbonization of water hyacinth
Published in Energy (Oxford) (01-09-2013)“…Hydrothermal carbonization of water hyacinth was experimentally conducted in the range of 30 min to 24 h at 240 °C, chemical and structural properties of…”
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16
Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide
Published in Proceedings of the National Academy of Sciences - PNAS (08-05-2018)“…Effective and safe delivery of the CRISPR/Cas9 gene-editing elements remains a challenge. Here we report the development of PEGylated nanoparticles (named…”
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17
Reversible Three-State Switching of Multicolor Fluorescence Emission by Multiple Stimuli Modulated FRET Processes within Thermoresponsive Polymeric Micelles
Published in Angewandte Chemie (International ed.) (12-07-2010)“…Micellar traffic lights: The title FRET system (FRET=fluorescence resonance energy transfer) consists of one type of donor dye and two types of acceptor dyes…”
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18
In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing
Published in Proceedings of the National Academy of Sciences - PNAS (12-05-2015)“…Over the past two decades, enormous progress has been made in designing fluorescent sensors or probes for divalent metal ions. In contrast, the development of…”
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Effect of different salts on the foaming properties of model protein systems for infant formula
Published in Journal of dairy science (01-05-2024)“…This multiscale study aimed to evaluate the effects of different salts (NaCl, KCl, MgCl2, and CaCl2) on the foaming capacity (FC) and foam stability (FS) of…”
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20
Selective in vivo metabolic cell-labeling-mediated cancer targeting
Published in Nature chemical biology (01-04-2017)“…Metabolic labeling of the cell surface with a caged azide sugar enabled cleavage-mediated activation by enzymes overexpressed in cancer cells, allowing…”
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