Search Results - "Jiang, Zhenyan"

Molecular Basis of Artemisinin Derivatives Inhibition of Myeloid Differentiation Protein 2 by Combined in Silico and Experimental Study by Qiao, Sennan, Zhang, Hansi, Sun, Fei, Jiang, Zhenyan

“…Artemisinin (also known as Qinghaosu), an active component of the Qinghao extract, is widely used as antimalarial drug. Previous studies reveal that…”
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A Critical Comparison of Biomembrane Force Fields: Structure and Dynamics of Model DMPC, POPC, and POPE Bilayers by Pluhackova, Kristyna, Kirsch, Sonja A, Han, Jing, Sun, Liping, Jiang, Zhenyan, Unruh, Tobias, Böckmann, Rainer A

“…Atomistic molecular dynamics simulations have become an important source of information for the structure and dynamics of biomembranes at molecular detail…”
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Nanoscale cutting using self-excited microcantilever by Yang, Rui, Ogura, Ichiro, Jiang, ZhenYan, An, LinJun, Ashida, Kiwamu, Yabuno, Hiroshi

“…The application of self-excitation is proposed to improve the efficiency of the nanoscale cutting procedure based on use of a microcantilever in atomic force…”
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Origin, genetic diversity, adaptive evolution and transmission dynamics of Getah virus by Shi, Ning, Zhu, Xiangyu, Qiu, Xiangshu, Cao, Xinyu, Jiang, Zhenyan, Lu, Huijun, Jin, Ningyi

“…As a member of the Alphavirus, Getah virus (GETV) was becoming more serious and posing a serious threat to animal safety and public health. However, the…”
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Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening by Zhang, Hansi, Pluhackova, Kristyna, Jiang, Zhenyan, Böckmann, Rainer A.

“…Sphingosine-1-phosphate (S1P) is a lysophospholipid mediator carried by the HDL-associated apoM protein in blood, regulating many physiological processes by…”
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Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation by Xiang, Hongrui, Tao, Yuexiao, Jiang, Zhenyan, Huang, Xian, Wang, Huizi, Cao, Wei, Li, Jia, Ding, Rui, Shen, Mingyi, Feng, Ru, Li, Linsen, Guan, Chenyang, Liu, Jiamin, Ni, Jun, Chen, Lei, Wang, Zhengting, Ye, Youqiong, Zhong, Qing, Liu, Junling, Zou, Qiang, Wu, Xuefeng

“…The suppressive function of regulatory T (Treg) cells is tightly controlled by nutrient-fueled mechanistic target of rapamycin complex 1 (mTORC1) activation,…”
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Molecular Mechanism of S1P Binding and Activation of the S1P1 Receptor by Jiang, Zhenyan, Zhang, Hansi

“…Sphingosine-1-phosphate (S1P) is a lipidic mediator in mammals that functions either as a second messenger or as a ligand. In the latter case, it is…”
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Molecular Mechanism of S1P Binding and Activation of the S1P 1 Receptor by Jiang, Zhenyan, Zhang, Hansi

“…Sphingosine-1-phosphate (S1P) is a lipidic mediator in mammals that functions either as a second messenger or as a ligand. In the latter case, it is…”
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Association between Insulin Resistance, Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in Chinese Adults by Ying, Xin, Jiang, Yan, Qian, Yafang, Jiang, Zhenyan, Song, Zhenya, Zhao, Changjun

“…The aim of this study was to assess the association between insulin resistance, metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) in Chinese…”
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Curvature effect and stabilize ruptured membrane of BAX derived peptide studied by molecular dynamics simulations by Jiang, Zhenyan, Zhang, Hansi

“…BAX protein plays a key role in mitochondrial membrane permeabilization and cytochrome c release upon apoptosis. The C-terminal transmembrane domain (TMD) of…”
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Mucus adhesion vs. mucus penetration? Screening nanomaterials for nasal inhalation by MD simulation by Gao, Xiaoshu, Xiong, Yin, Chen, Hening, Gao, Xuheng, Dai, Jiaxin, Zhang, Yutong, Zou, Wanhang, Gao, Yang, Jiang, Zhenyan, Han, Bing

“…Nanocarrier-aided drug delivery techniques have improved the absorption and permeability of drugs in nose-to-brain delivery. However, the molecular properties…”
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Tumor Suppressor Adenomatous Polyposis Coli Sustains Dendritic Cell Tolerance through IL-10 in a β-Catenin-Dependent Manner by Cao, Wei, Liu, Jiamin, Jiang, Zhenyan, Tao, Yuexiao, Wang, Huizi, Li, Jia, Ni, Jun, Wu, Xuefeng

“…Dendritic cells (DC) play important roles in balancing immunity and tolerance, in which β-catenin signaling plays an important role, yet the underlying…”
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Ubc13 Promotes K63-Linked Polyubiquitination of NLRP3 to Activate Inflammasome by Ni, Jun, Guan, Chenyang, Liu, Hua, Huang, Xian, Yue, Jinnan, Xiang, Hongrui, Jiang, Zhenyan, Tao, Yuexiao, Cao, Wenyi, Liu, Jiamin, Wang, Zhengting, Wang, Yugang, Wu, Xuefeng

“…NLRP3 inflammasome plays an important role in innate immune system through recognizing pathogenic microorganisms and danger-associated molecules…”
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Association of body mass index, waist circumference, and metabolic syndrome with serum cystatin C in a Chinese population by Ying, Xin, Jiang, Yan, Qin, Guangming, Qian, Yafang, Shen, Xiaoru, Jiang, Zhenyan, Zheng, Shu, Song, Zhenya

“…The aim of the study was to evaluate the association of body mass index (BMI), waist circumference (WC), and metabolic syndrome (MetS) with serum cystatin C…”
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Insight into the binding of ACE-inhibitory peptides to angiotensin-converting enzyme: a molecular simulation by Jiang, Zhenyan, Zhang, Hansi, Bian, Xuefeng, Li, Jingfeng, Li, Jing, Zhang, Hui

“…Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in the regulation of blood pressure by converting angiotensin I to…”
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Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists by Zhang, Xiaozheng, Cui, Fengchao, Chen, Hongqian, Zhang, Tianshu, Yang, Kecheng, Wang, Yibo, Jiang, Zhenyan, Rice, Kenner C, Watkins, Linda R, Hutchinson, Mark R, Li, Yunqi, Peng, Yinghua, Wang, Xiaohui

“…The opioid inactive isomer (+)-naltrexone is one of the rare Toll-like receptor 4 (TLR4) antagonists with good blood–brain barrier (BBB) permeability, which is…”
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SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation by Guan, Chenyang, Huang, Xian, Yue, Jinnan, Xiang, Hongrui, Shaheen, Samina, Jiang, Zhenyan, Tao, Yuexiao, Tu, Jun, Liu, Zhenshan, Yao, Yufeng, Yang, Wen, Hou, Zhaoyuan, Liu, Junling, Yang, Xiao-Dong, Zou, Qiang, Su, Bing, Liu, Zhiduo, Ni, Jun, Cheng, Jinke, Wu, Xuefeng

“…( ) infection of macrophage induces NLRC4 inflammasome-mediated production of the pro-inflammatory cytokines IL-1β. Post-translational modifications on NLRC4…”
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Allostery in BAX protein activation by Jiang, Zhenyan, Zhang, Hansi, Böckmann, Rainer A.

“…BAX is a member of the proapoptotic BCL-2 family of proteins, which is involved in the regulation of the intrinsic pathway of apoptosis. In the process of…”
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TMED4 facilitates Treg suppressive function via ROS homeostasis in tumor and autoimmune mouse models by Jiang, Zhenyan, Wang, Huizi, Wang, Xiaoxia, Duo, Hongrui, Tao, Yuexiao, Li, Jia, Li, Xin, Liu, Jiamin, Ni, Jun, Wu, Emily Jiatong, Xiang, Hongrui, Guan, Chenyang, Wang, Xinyu, Zhang, Kun, Zhang, Peng, Hou, Zhaoyuan, Liu, Yong, Wang, Zhengting, Su, Bing, Li, Bo, Hao, Youjin, Li, Bin, Wu, Xuefeng

“…Endoplasmic reticulum stress (ERS) plays crucial roles in maintaining regulatory T cells (Treg) stability and function, yet the underlying mechanism remains…”
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Association of the apolipoprotein B/apolipoprotein A-I ratio and low-density lipoprotein cholesterol with insulin resistance in a Chinese population with abdominal obesity by Ying, Xin, Qian, Yafang, Jiang, Yan, Jiang, Zhenyan, Song, Zhenya, Zhao, Changjun

“…The aim of this study is to assess the relationships among the apolipoprotein B/apolipoprotein A-I ratio (apoB/apoA-I ratio), low-density lipoprotein…”
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