Search Results - "Jiang, Zebo"

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    Tetrandrine activates STING/TBK1/IRF3 pathway to potentiate anti-PD-1 immunotherapy efficacy in non-small cell lung cancer by Tan, Yan, Zhu, Qiancheng, Yang, Meilin, Yang, Fan, Zeng, Qi, Jiang, Zebo, Li, Dan

    Published in Pharmacological research (01-09-2024)
    “…The efficacy of PD-1 therapy in non-small cell lung cancer (NSCLC) patients remains unsatisfactory. Activating the STING pathway is a promising strategy to…”
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  2. 2

    Cordycepin Inhibits Drug-resistance Non-small Cell Lung Cancer Progression by Activating AMPK Signaling Pathway by Wei, Chunli, Yao, Xiaojun, Jiang, Zebo, Wang, Yuwei, Zhang, Dianzheng, Chen, Xi, Fan, Xingxing, Xie, Chun, Cheng, Jingliang, Fu, Junjiang, Leung, Elaine Lai-Han

    Published in Pharmacological research (01-06-2019)
    “…[Display omitted] Lung cancer is the most commonly diagnosed cancer worldwide and it is also the most leading cause of cancer-related deaths. Although multiple…”
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    Anti-breast cancer-induced cardiomyopathy: Mechanisms and future directions by Liu, Chunping, Chen, Huiqi, Guo, Sien, Liu, Qiaojing, Chen, Zhijun, Huang, Haiding, Zhao, Qi, Li, Longmei, Cen, Huan, Jiang, Zebo, Luo, Qiyuan, Chen, Xiaoling, Zhao, Jiaxiong, Chen, Wensheng, Yang, Phillip C., Wang, Lei

    Published in Biomedicine & pharmacotherapy (01-10-2023)
    “…With the progression of tumor treatment, the 5-year survival rate of breast cancer is close to 90%. Cardiovascular toxicity caused by chemotherapy has become a…”
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  5. 5

    Immunity: Psoriasis comorbid with atherosclerosis by Liu, Chunping, Chen, Huiqi, Liu, Yanjiao, Huang, Haiding, Yu, Wanling, Du, Tingting, Long, Xinyao, Chen, Xinming, Chen, Zhijun, Guo, Sien, Li, Jinxin, Jiang, Zebo, Wang, Lei, Lu, Chuanjian

    Published in Frontiers in immunology (15-12-2022)
    “…Psoriasis is an immune-mediated, persistent inflammatory disease with a genetic predisposition, and the involvement of multiple organs in psoriasis remains…”
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    Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury by Xu, Duo, Yang, Fan, Chen, Jiayao, Zhu, Tianxing, Wang, Fen, Xiao, Yitai, Liang, Zibin, Bi, Lei, Huang, Guolong, Jiang, Zebo, Shan, Hong, Li, Dan

    Published in Acta pharmaceutica Sinica. B (01-05-2023)
    “…Acute lung injury (ALI), as a common clinical emergency, is pulmonary edema and diffuse lung infiltration caused by inflammation. The lack of non-invasive…”
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  8. 8

    Identification of a Novel Protein Arginine Methyltransferase 5 Inhibitor in Non-small Cell Lung Cancer by Structure-Based Virtual Screening by Wang, Qianqian, Xu, Jiahui, Li, Ying, Huang, Jumin, Jiang, Zebo, Wang, Yuwei, Liu, Liang, Leung, Elaine Lai Han, Yao, Xiaojun

    Published in Frontiers in pharmacology (01-03-2018)
    “…Protein arginine methyltransferase 5 (PRMT5) is able to regulate gene transcription by catalyzing the symmetrical dimethylation of arginine residue of histone,…”
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  9. 9

    Krukovine Suppresses KRAS-Mutated Lung Cancer Cell Growth and Proliferation by Inhibiting the RAF-ERK Pathway and Inactivating AKT Pathway by Lai, Huanling, Wang, Yuwei, Duan, Fugang, Li, Ying, Jiang, Zebo, Luo, Lianxiang, Liu, Liang, Leung, Elaine L H, Yao, Xiaojun

    Published in Frontiers in pharmacology (22-08-2018)
    “…Oncogenic activation of the KRAS gene via point mutations occurs in 20-30% of patients with non-small cell lung cancer (NSCLC). The RAS-RAF-ERK and…”
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    Gossypol Inhibits Non-small Cell Lung Cancer Cells Proliferation by Targeting EGFRL858R/T790M by Wang, Yuwei, Lai, Huanling, Fan, Xingxing, Luo, Lianxiang, Duan, Fugang, Jiang, Zebo, Wang, Qianqian, Leung, Elaine Lai Han, Liu, Liang, Yao, Xiaojun

    Published in Frontiers in pharmacology (09-07-2018)
    “…Background: Overexpression of epidermal growth factor receptor (EGFR) has been reported to be implicated in the pathogenesis of non-small cell lung cancer…”
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    STING-targeted PET tracer for early assessment of tumor immunogenicity in colorectal cancer after chemotherapy by Xu, Duo, Lu, Xin, Yang, Fan, Jiang, Zebo, Yang, Shirui, Bi, Lei, Liu, Jiani, Shan, Hong, Li, Dan

    “…Purpose To optimize chemotherapy regimens and improve the effectiveness of chemotherapy combined with immunotherapy, a PET tracer specifically targeting the…”
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  14. 14

    pH-sensitive molybdenum (Mo)-based polyoxometalate nanoclusters have therapeutic efficacy in inflammatory bowel disease by counteracting ferroptosis by Yang, Fan, Chen, Yuechuan, Xiao, Yitai, Jiang, Hailong, Jiang, Zebo, Yang, Meilin, Li, Mengzhu, Su, Yonghui, Yan, Zhixiang, Lin, Yong, Li, Dan

    Published in Pharmacological research (01-02-2023)
    “…Current therapeutic drugs for ulcerative colitis (UC) remained inadequate due to drug dependence and unacceptable adverse events. Reactive oxygen species (ROS)…”
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    STING agonist-based hydrogel enhances immune activation in synergy with radiofrequency ablation for hepatocellular carcinoma treatment by Ao, Feng, Li, Xi, Tan, Yan, Jiang, Zebo, Yang, Fan, Guo, Jingpei, Zhu, Qiancheng, Chen, Zhongguo, Zhou, Bin, Zhang, Ke, Li, Dan

    Published in Journal of controlled release (01-05-2024)
    “…Immunosuppression caused by incomplete radiofrequency ablation (iRFA) is a crucial factor affecting the effectiveness of RFA for solid tumors. However, little…”
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  16. 16

    Bi/Se-Based Nanotherapeutics Sensitize CT Image-Guided Stereotactic Body Radiotherapy through Reprogramming the Microenvironment of Hepatocellular Carcinoma by Liu, Jiani, Chen, Jiayao, Liu, Hongxing, Zhang, Ke, Zeng, Qi, Yang, Shuai, Jiang, Zebo, Zhang, Xiaoting, Chen, Tianfeng, Li, Dan, Shan, Hong

    Published in ACS applied materials & interfaces (15-09-2021)
    “…The particular characteristics of hypoxia, immune suppression in the tumor microenvironment, and the lack of accurate imaging guidance lead to the limited…”
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  17. 17

    Modulation of gut microbiota to overcome resistance to immune checkpoint blockade in cancer immunotherapy by Huang, Jumin, Jiang, Zebo, Wang, Yuwei, Fan, Xiaoqing, Cai, Jun, Yao, Xiaojun, Liu, Liang, Huang, Jun, He, Jianxing, Xie, Chun, Wu, Qibiao, Cao, Yabing, Leung, Elaine Lai-Han

    Published in Current opinion in pharmacology (01-10-2020)
    “…[Display omitted] Immune checkpoint blockade therapies that target CTLA-4 and PD-1/PD-L1 have ushered in a new era of cancer treatment. Nevertheless, a…”
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    Artificial intelligence-based collaborative filtering method with ensemble learning for personalized lung cancer medicine without genetic sequencing by Luo, Shengda, Xu, Jiahui, Jiang, Zebo, Liu, Lei, Wu, Qibiao, Leung, Elaine Lai-Han, Leung, Alex Po

    Published in Pharmacological research (01-10-2020)
    “…[Display omitted] In personalized medicine, many factors influence the choice of compounds. Hence, the selection of suitable medicine for patients with…”
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  19. 19

    Lu3+-based nanoprobe for virtual non-contrast CT imaging of hepatocellular carcinoma by Chen, Jiayao, Liu, Jiani, Xu, Duo, Liu, Junfeng, Chen, Xiaojun, Yang, Shuai, Yin, Pan, Jiang, Zebo, Mei, Chaoming, Zhang, Xiaoting, Wang, Lizhu, Zhang, Ke, Zhou, Bin, Shan, Hong, Li, Dan, Pang, Pengfei

    Published in Journal of controlled release (01-09-2022)
    “…Transcatheter arterial chemoembolization (TACE), the mainstream treatment for hepatocellular carcinoma (HCC), is a method of blocking tumor blood vessels with…”
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  20. 20

    Inhibition of JNK/c-Jun-ATF2 Overcomes Cisplatin Resistance in Liver Cancer through down-Regulating Galectin-1 by Yang, Fan, Li, Mengzhu, Xu, Duo, Jiang, Zebo, Jiang, Hailong, Xiao, Yitai, Mei, Chaoming, Yang, Meilin, Chen, Congmin, Zhou, Bin, He, Bailiang, Shan, Hong, Pang, Pengfei, Li, Dan

    “…Due to drug resistance, the clinical response to cisplatin (CDDP) from patients with liver cancer is unsatisfactory. The alleviation or overcoming of CDDP…”
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