Search Results - "Jiang, Xin Guo"
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Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis
Published in Nature communications (10-05-2017)“…Hyperactivated Ras regulates many oncogenic pathways in several malignant human cancers including glioblastoma and it is an attractive target for cancer…”
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2
Identification of distinct blood-based biomarkers in early stage of Parkinson’s disease
Published in Neurological sciences (01-04-2020)“…Parkinson’s disease (PD) is a slowly progressive geriatric disease, which can be one of the leading causes of serious socioeconomic burden in the aging…”
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3
Cationic albumin-conjugated pegylated nanoparticles as novel drug carrier for brain delivery
Published in Journal of controlled release (20-10-2005)“…In this paper, a novel drug carrier for brain delivery, cationic bovine serum albumin (CBSA) conjugated with poly(ethyleneglycol)–poly(lactide) (PEG–PLA)…”
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4
Determination of sulphasalazine and its main metabolite sulphapyridine and 5-aminosalicylic acid in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-02-2011)“…A simple and sensitive liquid chromatography/positive-ion electrospray ionization mass spectrometry (LC–ESI-MS/MS) method has been developed for the…”
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5
Recombinant Tissue Plasminogen Activator-conjugated Nanoparticles Effectively Targets Thrombolysis in a Rat Model of Middle Cerebral Artery Occlusion
Published in Current medical science (01-06-2018)“…Summary The efficacy and safety of recombinant tissue plasminogen activator (rtPA) need to be improved due to its low bioavailability and requirement of large…”
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6
Birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults
Published in European journal of endocrinology (01-10-2006)“…Objective: To investigate the association between birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults. Research…”
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7
Association of neck circumference and cognitive impairment among Chinese elderly
Published in Brain and behavior (01-03-2018)“…Objectives To investigate the association between neck circumference (NC) and cognitive impairment and interactions between relevant variables to the risk of…”
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8
Anti-CD69 monoclonal antibody treatment inhibits airway inflammation in a mouse model of asthma
Published in Journal of Zhejiang University. B. Science (01-07-2015)“…Objective Airway inflammation and airway hyper-responsiveness (AHR) are principle pathological manifestations of asthma. Cluster of differentiation 69 (CD69)…”
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9
Effect of lactoferrin- and transferrin-conjugated polymersomes in brain targeting: in vitro and in vivo evaluations
Published in Acta pharmacologica Sinica (01-02-2010)“…Aim: To evaluate the effect of lactoferrin (Lf) and transferrin (Tf) in brain targeting. Methods: Polymersomes (PSs), employed as vectors, were conjugated with…”
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10
Preparation of ion-activated in situ gel systems of scopolamine hydrobromide and evaluation of its antimotion sickness efficacy
Published in Acta pharmacologica Sinica (01-04-2007)“…Aim: To develop a novel, in situ gel system for nasal delivery of scopolamine hydrobromide (SCOP) and study its efficacy on motion sickness. Methods: SCOP in…”
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11
Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography–tandem mass spectrometry
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-07-2010)“…A precise and sensitive liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for simultaneous determination of vinpocetine (VP) and its primary…”
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12
Changes in rates, methods and characteristics of suicide attempters over a 15-year period: comparison between Stockholm, Sweden, and Würzburg, Germany
Published in Social Psychiatry and Psychiatric Epidemiology (01-11-2011)“…Purpose To investigate age and sex-specific changes in rates, methods used and characteristics of suicide attempters receiving medical care, over a 15-year…”
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13
Obesity and its associations with hypertension and type 2 diabetes among Chinese adults age 40 years and over
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-11-2009)“…Abstract Aim To investigate the prevalence of obesity in a Chinese community according to the World Health Organization recommended criteria for Asians in 2000…”
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14
Life time suicidal thoughts in an urban community in Hanoi, Vietnam
Published in BMC public health (26-03-2006)“…Suicidal thought is a risk factor and a stage in the suicidal process from planning to attempting and dying by suicide. To date, studies on suicidal thought in…”
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15
The association of weight status with cognitive impairment in the elderly population of a Shanghai suburb
Published in Asia Pacific journal of clinical nutrition (01-01-2013)“…Objective: A population-based survey was conducted to analyze the association of under-weight, blood pressure, glucose and lipid metabolism with cognitive…”
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16
Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration
Published in Cancer research (Chicago, Ill.) (15-12-2006)“…Patients with malignant gliomas have a poor prognosis because these tumors do not respond well to conventional treatments. Studies of glioma xenografts suggest…”
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17
TRPC6 mRNA levels in peripheral leucocytes of patients with Alzheimer's disease and mild cognitive impairment: A case-control study
Published in Progress in neuro-psychopharmacology & biological psychiatry (08-06-2019)“…Transient receptor potential canonical (TRPC) 6 inhibits Aβ in Alzheimer's disease (AD) mouse brain and improves the behavioral performance. To evaluate the…”
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18
Increased serum levels of interleukin-18, -23 and -17 in Chinese patients with Alzheimer's disease
Published in Dementia and geriatric cognitive disorders (01-01-2014)“…To evaluate the serum levels of interleukin (IL)-18, IL-23 and IL-17 in Chinese patients with Alzheimer's disease (AD), and explore correlations between the…”
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IL-18 induced IL-23/IL-17 expression impairs Aβ clearance in cultured THP-1 and BV2 cells
Published in Cytokine (Philadelphia, Pa.) (01-07-2019)“…•The involvement of IL-18, IL-23 and IL-17 on Aβ clearance is still unclear.•Aβ42 incubation with THP-1/BV2 could increase IL-18, IL-23 and IL-17…”
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Serum haptoglobin in Chinese patients with Alzheimer’s disease and mild cognitive impairment: A case-control study
Published in Brain research bulletin (01-03-2018)“…•A case-control study from a population survey regarding serum Haptoglobin (Hp).•Serum Hp level increased from healthy controls through MCI cases to AD…”
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