Search Results - "Jiang, Jason Y"
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Direct visualization of cAMP signaling in primary cilia reveals up-regulation of ciliary GPCR activity following Hedgehog activation
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-2019)“…The primary cilium permits compartmentalization of specific signaling pathways, including elements of the Hedgehog (Hh) pathway. Hh transcriptional activity is…”
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Epigenetic Regulation of Corneal Epithelial Differentiation by TET2
Published in International journal of molecular sciences (02-02-2023)“…Epigenetic DNA modification by 5-hydroxymethylcytosine (5hmC), generated by the Ten-eleven translocation (TET) dioxygenases, regulates diverse biological…”
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Interrogating cyclic AMP signaling using optical approaches
Published in Cell calcium (Edinburgh) (01-06-2017)“…Graphical abstract…”
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Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca2
Published in International journal of molecular sciences (21-03-2017)“…Metabotropic glutamate receptors (mGluRs) associated with the slow phase of the glutamatergic signaling pathway in neurons of the central nervous system have…”
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Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α
Published in The Journal of biological chemistry (17-01-2014)“…Metabotropic glutamate receptor 1α (mGluR1α), a member of the family C G protein-coupled receptors, is emerging as a potential drug target for various…”
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Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca super(2+)
Published in International journal of molecular sciences (01-03-2017)“…Metabotropic glutamate receptors (mGluRs) associated with the slow phase of the glutamatergic signaling pathway in neurons of the central nervous system have…”
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Journal Article -
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Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca 2
Published in International journal of molecular sciences (21-03-2017)“…Metabotropic glutamate receptors (mGluRs) associated with the slow phase of the glutamatergic signaling pathway in neurons of the central nervous system have…”
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Extracellular Calcium Modulates Actions of Orthosteric and Allosteric Ligands on Metabotropic Glutamate Receptor 1αThis work was supported, in whole or in part, by National Institutes of Health Grants GM081749-01 (to J. J. Y.), DK078331 (to E. M. B.), and NS055179 (to R. A. H.). This work was also supported by a Brains and Behavior fellowship (to Y. J.)
Published in The Journal of biological chemistry (01-01-2014)“…Metabotropic glutamate receptor 1α (mGluR1α), a member of the family C G protein-coupled receptors, is emerging as a potential drug target for various…”
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Journal Article