Search Results - "Jiang, Hanwei"

A homozygous FANCM frameshift pathogenic variant causes male infertility by Yin, Hao, Ma, Hui, Hussain, Sajjad, Zhang, Huan, Xie, Xuefeng, Jiang, Long, Jiang, Xiaohua, Iqbal, Furhan, Bukhari, Ihtisham, Jiang, Hanwei, Ali, Asim, Zhong, Liangwen, Li, Tao, Fan, Suixing, Zhang, Beibei, Gao, Jianing, Li, Yang, Nazish, Jabeen, Khan, Teka, Khan, Manan, Zubair, Muhammad, Hao, Qiaomei, Fang, Hui, Huang, Jun, Huleihel, Mahmoud, Sha, Jiahao, Pandita, Tej K., Zhang, Yuanwei, Shi, Qinghua

“…Fanconi anemia (FA) genes play important roles in spermatogenesis. In mice, disruption of Fancm impairs male fertility and testicular integrity, but whether…”
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Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels by Yin, Shi, Jiang, Xiaohua, Jiang, Hanwei, Gao, Qian, Wang, Fang, Fan, Suixing, Khan, Teka, Jabeen, Nazish, Khan, Manan, Ali, Asim, Xu, Peng, Pandita, Tej K, Fan, Heng-Yu, Zhang, Yuanwei, Shi, Qinghua

“…Proper oocyte development is crucial for female fertility and requires timely and accurate control of gene expression. K (lysine) acetyltransferase 8 (KAT8),…”
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Nuclear translocation of MTL5 from cytoplasm requires its direct interaction with LIN9 and is essential for male meiosis and fertility by Zhang, Xingxia, Li, Ming, Jiang, Xiaohua, Ma, Hui, Fan, Suixing, Li, Yang, Yu, Changping, Xu, Jianze, Khan, Ranjha, Jiang, Hanwei, Shi, Qinghua

“…Meiosis is essential for the generation of gametes and sexual reproduction, yet the factors and underlying mechanisms regulating meiotic progression remain…”
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MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice by Jiang, Hanwei, Gao, Qian, Zheng, Wei, Yin, Shi, Wang, Liu, Zhong, Liangwen, Ali, Asim, Khan, Teka, Hao, Qiaomei, Fang, Hui, Sun, Xiaoling, Xu, Peng, Pandita, Tej K, Jiang, Xiaohua, Shi, Qinghua

“…Three waves of H2AX phosphorylation (γH2AX) have been observed in male meiotic prophase I: the first is ATM-dependent and occurs at leptonema, while the second…”
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UHRF1-repressed 5’-hydroxymethylcytosine is essential for the male meiotic prophase I by Pan, Hongjie, Jiang, Ning, Sun, Shenfei, Jiang, Hanwei, Xu, Jianze, Jiang, Xiaohua, Gao, Qian, Li, Liang, Wu, Haili, Zheng, Huajun, Qi, Qi, Li, Tianqi, Zhang, Meixing, Zhang, Lingling, Wan, Xiaofeng, Lin, Xinhua, Wong, Jiemin, Shi, Qinghua, Li, Runsheng

“…5’-hydroxymethylcytosine (5hmC), an important 5’-cytosine modification, is altered highly in order in male meiotic prophase. However, the regulatory mechanism…”
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ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression by Xu, Jianze, Gao, Jianing, Liu, Junyan, Huang, Xue, Zhang, Huan, Ma, Ao, Ye, Jingwei, Zhang, Xingxia, Li, Yang, Yang, Gang, Yin, Hao, Khan, Ranjha, Li, Tao, Fan, Suixing, Jiang, Xiaohua, Zhang, Yuanwei, Jiang, Hanwei, Ma, Hui, Shi, Qinghua

“…The DSB machinery, which induces the programmed DNA double-strand breaks (DSBs) in the leptotene and zygotene stages during meiosis, is suppressed before the…”
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Loss-of-function variants in KCTD19 cause non-obstructive azoospermia in humans by Liu, Junyan, Rahim, Fazal, Zhou, Jianteng, Fan, Suixing, Jiang, Hanwei, Yu, Changping, Chen, Jing, Xu, Jianze, Yang, Gang, Shah, Wasim, Zubair, Muhammad, Khan, Asad, Li, Yang, Shah, Basit, Zhao, Daren, Iqbal, Furhan, Jiang, Xiaohua, Guo, Tonghang, Xu, Peng, Xu, Bo, Wu, Limin, Ma, Hui, Zhang, Yuanwei, Zhang, Huan, Shi, Qinghua

“…Azoospermia is a significant cause of male infertility, with non-obstructive azoospermia (NOA) being the most severe type of spermatogenic failure. NOA is…”
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A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation by Fan, Suixing, Wang, Yuewen, Jiang, Hanwei, Jiang, Xiaohua, Zhou, Jianteng, Jiao, Yuying, Ye, Jingwei, Xu, Zishuo, Wang, Yue, Xie, Xuefeng, Zhang, Huan, Li, Yang, Liu, Wei, Zhang, Xiangjun, Ma, Hui, Shi, Baolu, Zhang, Yuanwei, Zubair, Muhammad, Shah, Wasim, Xu, Zhipeng, Xu, Bo, Shi, Qinghua

“…During meiosis, at least one crossover must occur per homologous chromosome pair to ensure normal progression of meiotic division and accurate chromosome…”
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Correction: A homozygous FANCM frameshift pathogenic variant causes male infertility by Yin, Hao, Ma, Hui, Hussain, Sajjad, Zhang, Huan, Xie, Xuefeng, Jiang, Long, Jiang, Xiaohua, Iqbal, Furhan, Bukhari, Ihtisham, Jiang, Hanwei, Ali, Asim, Zhong, Liangwen, Li, Tao, Fan, Suixing, Zhang, Beibei, Gao, Jianing, Li, Yang, Nazish, Jabeen, Khan, Teka, Khan, Manan, Zubair, Muhammad, Hao, Qiaomei, Fang, Hui, Huang, Jun, Huleihel, Mahmoud, Sha, Jiahao, Pandita, Tej K., Zhang, Yuanwei, Shi, Qinghua

“…Hao Win, Hui Ma and Sajjad Hussain were incorrectly affiliated to ‘Department of Radiation Oncology, The Houston Methodist Research Institute, Houston, TX…”
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Identification of pathogenic mutations from nonobstructive azoospermia patients by Jiang, Hanwei, Zhang, Yuanwei, Ma, Hui, Fan, Suixing, Zhang, Huan, Shi, Qinghua

“…It is estimated that approximately 25% of nonobstructive azoospermia (NOA) cases are caused by single genetic anomalies, including chromosomal aberrations and…”
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Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans by Fan, Suixing, Jiao, Yuying, Khan, Ranjha, Jiang, Xiaohua, Javed, Abdul Rafay, Ali, Asim, Zhang, Huan, Zhou, Jianteng, Naeem, Muhammad, Murtaza, Ghulam, Li, Yang, Yang, Gang, Zaman, Qumar, Zubair, Muhammad, Guan, Haiyang, Zhang, Xingxia, Ma, Hui, Jiang, Hanwei, Ali, Haider, Dil, Sobia, Shah, Wasim, Ahmad, Niaz, Zhang, Yuanwei, Shi, Qinghua

“…Human infertility is a multifactorial disease that affects 8%–12% of reproductive-aged couples worldwide. However, the genetic causes of human infertility are…”
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M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination by Li, Yang, Wu, Yufan, Khan, Ihsan, Zhou, Jianteng, Lu, Yue, Ye, Jingwei, Liu, Junyan, Xie, Xuefeng, Hu, Congyuan, Jiang, Hanwei, Fan, Suixing, Zhang, Huan, Zhang, Yuanwei, Jiang, Xiaohua, Xu, Bo, Ma, Hui, Shi, Qinghua

“…Following meiotic recombination, each pair of homologous chromosomes acquires at least one crossover, which ensures accurate chromosome segregation and allows…”
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Biallelic HFM1 variants cause non-obstructive azoospermia with meiotic arrest in humans by impairing crossover formation to varying degrees by Xie, Xuefeng, Murtaza, Ghulam, Li, Yang, Zhou, Jianteng, Ye, Jingwei, Khan, Ranjha, Jiang, Long, Khan, Ihsan, Zubair, Muhammad, Yin, Hao, Jiang, Hanwei, Liu, Wei, Shi, Baolu, Hou, Xiaoning, Gong, Chenjia, Fan, Suixing, Wang, Yuewen, Jiang, Xiaohua, Zhang, Yuanwei, Zhang, Huan, Ma, Hui, Shi, Qinghua

“…Abstract STUDY QUESTION Do variants in helicase for meiosis 1 (HFM1) account for male infertility in humans? SUMMARY ANSWER Biallelic variants in HFM1 cause…”
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The testis-specifically expressed Dpep3 is not essential for male fertility in mice by Xie, Yubin, Khan, Ranjha, Wahab, Fazal, Hussain, Hafiz Muhammad Jafar, Ali, Asim, Ma, Hui, Jiang, Hanwei, Xu, Jianze, Zaman, Qamar, Khan, Mazhar, Jiang, Xiaohua, Shi, Qinghua

“…More than 2300 genes have been reported to be involved in spermatogenesis but the functional roles of most genes in male fertility remain to be elucidated. In…”
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Preparation and Properties of a Phosphorus-Free Intrinsic Flame-Retardant and High Thermal Resistant Polybenzoxazine with Good Degradability by Jiang, Hanwei, Chen, Haidong, Li, Jiaming, Chen, Kun, Zhou, Yixue, Ran, Qichao, Xu, Yi

“…Polybenzoxazines are a type of thermosetting resin with good thermal resistance. A flame-retardant and degradable polybenzoxazine (ERY-a) was synthesized by a…”
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Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans by Fan, Suixing, Jiao, Yuying, Khan, Ranjha, Jiang, Xiaohua, Javed, Abdul Rafay, Ali, Asim, Zhang, Huan, Zhou, Jianteng, Naeem, Muhammad, Murtaza, Ghulam, Li, Yang, Yang, Gang, Zaman, Qumar, Zubair, Muhammad, Guan, Haiyang, Zhang, Xingxia, Ma, Hui, Jiang, Hanwei, Ali, Haider, Dil, Sobia, Shah, Wasim, Ahmad, Niaz, Zhang, Yuanwei, Shi, Qinghua

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A TOP6BL mutation abolishes meiotic DNA double-strand break formation and causes human infertility by Jiao, Yuying, Fan, Suixing, Jabeen, Nazish, Zhang, Huan, Khan, Ranjha, Murtaza, Ghulam, Jiang, Hanwei, Ali, Asim, Li, Yang, Bao, Jianqiang, Zhang, Beibei, Xu, Jianze, Xu, Bo, Hussain, Hafiz Muhammad Jafar, Zaman, Qumar, Khan, Ihsan, Bukhari, Ihtisham, Iqbal, Furhan, Yousaf, Ayesha, Dil, Sobia, Khan, Manan, Ahmad, Niaz, Ma, Hui, Jiang, Xiaohua, Zhang, Yuanwei, Shi, Qinghua

“…[Display omitted] Meiosis is pivotal for sexual reproduction and fertility. Meiotic programmed DNA double-strand breaks (DSBs) initiate homologous…”
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Ndrg3 gene regulates DSB repair during meiosis through modulation the ERK signal pathway in the male germ cells by Pan, Hongjie, Zhang, Xuan, Jiang, Hanwei, Jiang, Xiaohua, Wang, Liu, Qi, Qi, Bi, Yuan, Wang, Jian, Shi, Qinghua, Li, Runsheng

“…The N-myc downstream regulated gene (NDRG) family consists of 4 members, NDRG-1, -2, -3, -4. Physiologically, we found Ndrg3 , a critical gene which led to…”
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Chlorophyll deficient 3, Encoding a Putative Potassium Efflux Antiporter, Affects Chloroplast Development Under High Temperature Conditions in Rice (Oryza sativa L.) by Luo, Rongjian, Jiang, Hanwei, Lv, Yusong, Hu, Shikai, Sheng, Zhonghua, Shao, Gaoneng, Tang, Shaoqing, Hu, Peisong, Wei, Xiangjin

“…Potassium efflux antiporters (KEAs) play important roles in the regulation of monovalent cation efflux to maintain ion homeostasis in plant cells; however,…”
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RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes by Ma, Hui, Li, Tao, Xie, Xuefeng, Jiang, Long, Ye, Jingwei, Gong, Chenjia, Jiang, Hanwei, Fan, Suixing, Zhang, Huan, Shi, Baolu, Zhang, Beibei, Jiang, Xiaohua, Li, Yang, Zhou, Jianteng, Xu, Jianze, Zhang, Xingxia, Hou, Xiaoning, Yin, Hao, Zhang, Yuanwei, Shi, Qinghua

“…Faithful segregation of X and Y chromosomes requires meiotic recombination to form a crossover between them in the pseudoautosomal region (PAR). Unlike…”
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