Search Results - "Jiang, Allen Y."

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  1. 1

    Combinatorial development of nebulized mRNA delivery formulations for the lungs by Jiang, Allen Y., Witten, Jacob, Raji, Idris O., Eweje, Feyisayo, MacIsaac, Corina, Meng, Sabrina, Oladimeji, Favour A., Hu, Yizong, Manan, Rajith S., Langer, Robert, Anderson, Daniel G.

    Published in Nature nanotechnology (01-03-2024)
    “…Inhaled delivery of mRNA has the potential to treat a wide variety of diseases. However, nebulized mRNA lipid nanoparticles (LNPs) face several unique…”
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    Journal Article
  2. 2

    Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA by Jiang, Allen Y., Lathwal, Sushil, Meng, Sabrina, Witten, Jacob, Beyer, Emily, McMullen, Patrick, Hu, Yizong, Manan, Rajith S., Raji, Idris, Langer, Robert, Anderson, Daniel G.

    Published in Journal of the American Chemical Society (13-11-2024)
    “…Lipid nanoparticles (LNPs) have great potential to enable inhaled delivery of mRNA to treat pulmonary diseases. However, this potential has been limited by the…”
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  3. 3

    Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry by Li, Bowen, Raji, Idris O., Gordon, Akiva G. R., Sun, Lizhuang, Raimondo, Theresa M., Oladimeji, Favour A., Jiang, Allen Y., Varley, Andrew, Langer, Robert S., Anderson, Daniel G.

    Published in Nature materials (01-07-2024)
    “…To unlock the full promise of messenger (mRNA) therapies, expanding the toolkit of lipid nanoparticles is paramount. However, a pivotal component of lipid…”
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    Journal Article