Search Results - "Jian-hua LIU"
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Carbapenem-resistant and colistin-resistant Escherichia coli co-producing NDM-9 and MCR-1
Published in The Lancet infectious diseases (01-03-2016)“…Given that colistin and carbapenem-resistant E coli can be found in retail meat, and that the resistance genes for crucial antimicrobials are located on…”
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Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study
Published in The Lancet infectious diseases (01-02-2016)“…Summary Background Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene transfer. During a…”
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Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1 -positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study
Published in The Lancet infectious diseases (01-04-2017)“…Summary Background The mcr-1 gene confers transferable colistin resistance. mcr-1 -positive Enterobacteriaceae (MCRPE) have attracted substantial medical,…”
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Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae
Published in mBio (03-03-2020)“…Transporters belonging to the chromosomally encoded resistance-nodulation-division (RND) superfamily mediate multidrug resistance in Gram-negative bacteria…”
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Dissemination of the mcr-1 colistin resistance gene
Published in The Lancet infectious diseases (01-03-2016)“…Since our first report on plasmid-mediated colistin resistance gene mcr-1,1 strains previously collected in seven countries (Denmark, the Netherlands, Laos,…”
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A Novel Transferable Resistance-Nodulation-Division Pump Gene Cluster, tmexCD2-toprJ2 , Confers Tigecycline Resistance in Raoultella ornithinolytica
Published in Antimicrobial agents and chemotherapy (18-03-2021)“…We recently identified a novel plasmid-mediated resistance-nodulation-division (RND)-type efflux pump gene cluster, , in that conferred resistance to multiple…”
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Cucurbitacin B regulates lung cancer cell proliferation and apoptosis via inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis
Published in Pharmaceutical biology (01-12-2022)“…Lung cancer, the most common type of cancer, has a high mortality rate. Cucurbitacin B (CuB), a natural compound extracted from Cucurbitaceae plants, has…”
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mcr-1-Harboring Salmonella enterica Serovar Typhimurium Sequence Type 34 in Pigs, China
Published in Emerging infectious diseases (01-02-2017)“…We detected the mcr-1 gene in 21 (14.8%) Salmonella isolates from pigs at slaughter; 19 were serovar Typhimurium sequence type 34. The gene was located on…”
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Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes
Published in Journal of antimicrobial chemotherapy (01-10-2018)“…The initial report of the mcr-1 (mobile colistin resistance) gene has led to many reports of mcr-1 variants and other mcr genes from different bacterial…”
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Diastereodivergent chiral aldehyde catalysis for asymmetric 1,6-conjugated addition and Mannich reactions
Published in Nature communications (23-10-2020)“…Chiral aldehyde catalysis is a burgeoning strategy for the catalytic asymmetric α-functionalization of aminomethyl compounds. However, the reaction types are…”
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Biofilm promoted current generation of Pseudomonas aeruginosa microbial fuel cell via improving the interfacial redox reaction of phenazines
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-10-2017)“…Bacteria biofilm plays a key role in current generation of microbial fuel cells (MFCs), especially for the start-up stage. However, the detailed mechanism of…”
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Fitness Advantage of mcr-1 -Bearing IncI2 and IncX4 Plasmids in Vitro
Published in Frontiers in microbiology (27-02-2018)“…The objective of this study was to assess the impact of diverse plasmids bearing colistin resistance gene on host fitness. Forty-seven commensal isolates…”
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Graphene-reinforced aluminum matrix composites prepared by spark plasma sintering
Published in International journal of minerals, metallurgy and materials (01-06-2016)“…Graphene-reinforced 7055 aluminum alloy composites with different contents of graphene were prepared by spark plasma sintering(SPS). The structure and…”
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Dissemination of the Fosfomycin Resistance Gene fosA3 with CTX-M β-Lactamase Genes and rmtB Carried on IncFII Plasmids among Escherichia coli Isolates from Pets in China
Published in Antimicrobial Agents and Chemotherapy (01-04-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Catalytic asymmetric Tsuji–Trost α−benzylation reaction of N-unprotected amino acids and benzyl alcohol derivatives
Published in Nature communications (06-05-2022)“…Catalytic asymmetric Tsuji–Trost benzylation is a promising strategy for the preparation of chiral benzylic compounds. However, only a few such transformations…”
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Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer
Published in JNCI : Journal of the National Cancer Institute (01-04-2016)“…The TLR/MyD88 signaling pathway is an important driver of inflammation and cancer and is a possible target for antitumor therapy. We generated a MyD88…”
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Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6
Published in Autoimmunity (Chur, Switzerland) (17-11-2021)“…Exosomes isolated from mesenchymal stem cells (MSC) had shown beneficial effect on acute lung injury (ALI). However, the effective components in MSC-derived…”
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High-Throughput Metabolomics Evaluate the Efficacy of Total Lignans From Acanthophanax Senticosus Stem Against Ovariectomized Osteoporosis Rat
Published in Frontiers in pharmacology (29-05-2019)“…Postmenopausal osteoporosis (PMOP) is a common clinical illness in postmenopausal women, but there is no effective drug at present. Metabolomics approach was…”
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Increasing prevalence of extended-spectrum cephalosporin-resistant Escherichia coli in food animals and the diversity of CTX-M genotypes during 2003–2012
Published in Veterinary microbiology (27-08-2014)“…•CTX-M in 2815 Escherichia coli from food animals in China increased during 2003–2012.•Eighteen different types of CTX-M (including 4 novel enzymes) were…”
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Promoter regulatory mode evolution enhances the high multidrug resistance of tmexCD1-toprJ1
Published in mBio (08-05-2024)“…Antibiotic resistance could rapidly emerge from acquiring the mobile antibiotic resistance genes, which are commonly evolved from an intrinsic gene. The…”
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