Search Results - "Jian, Tunyu"

Ellagic acid ameliorates oxidative stress and insulin resistance in high glucose-treated HepG2 cells via miR-223/keap1-Nrf2 pathway by Ding, Xiaoqin, Jian, Tunyu, Wu, Yuexian, Zuo, Yuanyuan, Li, Jiawei, Lv, Han, Ma, Li, Ren, Bingru, Zhao, Lei, Li, Weilin, Chen, Jian

“…[Display omitted] •miR-223 could target keap1 and inhibit its expression.•miR-223 may be a marker of oxidative stress in high-glucose exposed HepG2…”
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Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice by Chen, Jian, Ren, Bingru, Li, Jing, Tong, Bei, Lv, Han, Li, Jiawei, Jian, Tunyu, Ding, Xiaoqin, Meng, Xiuhua

“…This study examines the effects of chicoric acid (CA) on nonalcoholic fatty liver disease (NAFLD) in high-fat-diet- (HFD-) fed C57BL/6 mice. CA treatment…”
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Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways by Jian, Tunyu, Ding, Xiaoqin, Wu, Yuexian, Ren, Bingru, Li, Weilin, Lv, Han, Chen, Jian

“…Ambient air particulate matter (PM) represents a class of heterogeneous substances present in polluted air, which contains many harmful components. Exposure to…”
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Phenolic profiles, antioxidant activity and inhibition of digestive enzymes of water caltrop pericarps by Lü, Han, Zuo, Yuanyuan, Meng, Xiuhua, Ding, Xiaoqin, Jian, Tunyu, Liu, Yan, Ren, Bingru, Chen, Jian, Li, Weilin

“…BACKGROUND Water caltrop (Trapa natans L.) is widely cultivated as a popular vegetable or fruit in Asian countries. In China, water caltrop pericarp is also…”
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Luteolin Alleviates Oxidative Stress in Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke via Modulation of the TRPV1 and CYP2A13/NRF2 Signaling Pathways by Zhou, Lina, Jian, Tunyu, Wan, Yan, Huang, Rizhong, Fang, Hailing, Wang, Yiwei, Liang, Chengyuan, Ding, Xiaoqin, Chen, Jian

“…The current study aims to investigate the therapeutic potential of luteolin (Lut), a naturally occurring flavonoid found in various medicinal plants, for…”
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Li-Hong Tang alleviates dextran sodium sulfate-induced colitis by regulating NRF2/HO-1 signaling pathway and gut microbiota by Gu, Hong, Tian, Yuwen, Xia, Jingjing, Deng, Xiaoyue, Chen, Jian, Jian, Tunyu, Ma, Jiong

“…Ulcerative colitis (UC) is marked by recurring inflammation. Existing treatments are ineffective and may have toxic side effects. Thus, new therapeutic agents…”
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Sesquiterpene glycoside isolated from loquat leaf targets gut microbiota to prevent type 2 diabetes mellitus in db/db mice by Wu, Ruoyun, Zhou, Lina, Chen, Yan, Ding, Xiaoqin, Liu, Yan, Tong, Bei, Lv, Han, Meng, Xiuhua, Li, Jing, Jian, Tunyu, Chen, Jian

“…According to ancient records, loquat leaf has been used as both a food and medicine in China for thousands of years. Sesquiterpene glycosides from loquat leaf…”
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Hepatoprotective Effect of Seed Coat of Euryale ferox Extract in Non-alcoholic Fatty Liver Disease Induced by High-fat Diet in Mice by Increasing IRs-1 and Inhibiting CYP2E1 by Jian, Tunyu, Yu, Chen, Ding, Xiaoqin, Chen, Jian, Li, Jiawei, Zuo, Yuanyuan, Ren, Bingru, Lv, Han, Li, Weilin

“…Non-alcoholic fatty liver disease (NAFLD), a common chronic liver disease characterized by hepatic steatosis, affects 30-40% of the population in the world…”
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Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways by Wu, Ruoyun, Jian, Tunyu, Ding, Xiaoqin, Lv, Han, Meng, Xiuhua, Ren, Bingru, Li, Jing, Chen, Jian, Li, Weilin

“…Loquat (Eriobotrya japonica Lindl.), a subtropical fruit tree native to Asia, is not only known to be nutritive but also beneficial for the treatment of…”
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Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice by Ding, Xiaoqin, Chen, Yan, Zhou, Lina, Wu, Ruoyun, Jian, Tunyu, Lyu, Han, Liu, Yan, Chen, Jian

“…Bisdemethoxycurcumin (BDMC), a principal and active component of edible turmeric, was previously found to have beneficial effects on metabolic diseases…”
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The Essential Oil from Acori Tatarinowii Rhizome (the Dried Rhizome of Acorus tatarinowii Schott) Prevents Hydrogen Peroxide-Induced Cell Injury in PC12 Cells: A Signaling Triggered by CREB/PGC-1α Activation by Wei, Min, Shan, Yu, Ding, Xiaoqin, Jian, Tunyu, Song, Pingping, Qian, Yiyun, Mahady, Gail B., Yan, Lu, Guan, Fuqin

“…Acori Tatarinowii Rhizome (ATR, the dried rhizome of Acorus tatarinowii Schott), a well-recognized traditional Chinese herbal medicine, is prescribed to treat…”
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Triterpene Acids of Loquat Leaf Improve Inflammation in Cigarette Smoking Induced COPD by Regulating AMPK/Nrf2 and NFκB Pathways by Jian, Tunyu, Ding, Xiaoqin, Li, Jiawei, Wu, Yuexian, Ren, Bingru, Li, Jing, Lv, Han, Chen, Jian, Li, Weilin

“…Cigarette smoking (CS) is believed to be an important inducement in the pathological development of chronic obstructive pulmonary disease (COPD), a progressive…”
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Four sesquiterpene glycosides from loquat ( Eriobotrya japonica ) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway by Li, Jiawei, Ding, Xiaoqin, Jian, Tunyu, Lü, Han, Zhao, Lei, Li, Jing, Liu, Yan, Ren, Bingru, Chen, Jian

“…Insulin resistance (IR), caused by impaired insulin signal and decreased insulin sensitivity, is generally responsible for the pathophysiology of type 2…”
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Polyphenol-rich Trapa quadrispinosa pericarp extract ameliorates high-fat diet induced non-alcoholic fatty liver disease by regulating lipid metabolism and insulin resistance in mice by Jian, Tunyu, Lü, Han, Ding, Xiaoqin, Wu, Yuexian, Zuo, Yuanyuan, Li, Jiawei, Chen, Jian, Gu, Hong

“…In China, (also called water caltrop) has long been used as a function food and folk medicine to treat diabetes mellitus for years. In the present study, the…”
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Molecular mechanisms conferring asymmetrical cross-resistance between tebufenozide and abamectin in Plutella xylostella by Yin, Qian, Qian, Lu, Song, Pingping, Jian, Tunyu, Han, ZhaoJun

“…Based on the confirmation of asymmetrical cross-resistance between abamectin and tebufenozide in Plutella xylostella, the present work proved that the…”
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Pirt Contributes to Uterine Contraction-Induced Pain in Mice by Wang, Changming, Wang, Zhongli, Yang, Yan, Zhu, Chan, Wu, Guanyi, Yu, Guang, Jian, Tunyu, Yang, Niuniu, Shi, Hao, Tang, Min, He, Qian, Lan, Lei, Liu, Qin, Guan, Yun, Dong, Xinzhong, Duan, Jinao, Tang, Zongxiang

“…Uterine contraction-induced pain (UCP) represents a common and severe form of visceral pain. Nerve fibers that innervate uterine tissue express the transient…”
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An integrative exploration of loquat leaf total sesquiterpene glycosides in treating insulin-resistant mice by serum and urine untargeted metabolomics analysis by Gai, Yanan, Li, Jiawei, Jian, Tunyu, Ding, Xiaoqin, Lyu, Han, Liu, Yan, Li, Jing, Ren, Bingru, Chen, Jian, Li, Weilin

“…Loquat leaf is approved to be beneficial in the treatment of diabetes. Total sesquiterpene glycosides (TSG), a major chemical component cluster, has potential…”
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TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch by Shi, Hao, He, Qian, Lan, Lei, Wu, Guanyi, Tang, Zongxiang, Wang, Zhongli, Wang, Changming, Yu, Guang, Yuan, Xiaolin, Zhu, Chan, Yang, Yan, Yang, Niuniu, Jian, Tunyu, Tang, Min

“…Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation…”
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Hepatoprotective Effect of Seed Coat ofEuryale ferox Extract in Non-alcoholic Fatty Liver Disease Induced by High-fat Diet in Mice by Increasing IRs-1 and Inhibiting CYP2E1 by Jian, Tunyu, Yu, Chen, Ding, Xiaoqin, Chen, Jian, Li, Jiawei, Zuo, Yuanyuan, Ren, Bingru, Lv, Han, Li, Weilin

“…Non-alcoholic fatty liver disease (NAFLD), a common chronic liver disease characterized by hepatic steatosis, affects 30-40% of the population in the world…”
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Microbiota and plant-derived vesicles that serve as therapeutic agents and delivery carriers to regulate metabolic syndrome by Niu, Guanting, Jian, Tunyu, Gai, Yanan, Chen, Jian

“…[Display omitted] The gut is a fundamental organ in controlling human health. Recently, researches showed that substances in the intestine can alter the course…”
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