Search Results - "Jian, Lingyan"

The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies by Bai, Ruixue, Li, Yunong, Jian, Lingyan, Yang, Yuehui, Zhao, Lin, Wei, Minjie

“…Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a…”
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Pharmacoeconomic Evaluation of Erlotinib for the Treatment of Pancreatic Cancer by Bao, Kunxi, Li, Xiaobing, He, Xiaojing, Jian, Lingyan

“…To evaluate the cost-effectiveness of gemcitabine and gemcitabine plus erlotinib as first-line treatments for advanced pancreatic cancer. On the basis of the…”
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DHW-208, A Novel Phosphatidylinositol 3-Kinase (PI3K) Inhibitor, Has Anti-Hepatocellular Carcinoma Activity Through Promoting Apoptosis and Inhibiting Angiogenesis by Wang, Shu, Wu, Yuting, Liu, Mingyue, Zhao, Qingchun, Jian, Lingyan

“…Hepatocellular carcinoma (HCC) is one of the most common tumors worldwide with high prevalence and lethality. Due to insidious onset and lack of early…”
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Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa by Zhao, Lei, Wang, Shiqi, Li, Xiaobing, He, Xiaojing, Jian, Lingyan

“…Abstract Fluoroquinolone resistance in Pseudomonas aeruginosa typically arises through site-specific mutations and overexpression of efflux pumps. In this…”
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Which Is the Most Appropriate PI3K Inhibitor for Breast Cancer Patients with or without PIK3CA Status Mutant? A Systematic Review and Network Meta-Analysis by Jian, Lingyan, Zhao, Qingchun, Zhang, Guibin, Liu, Naiming, Lian, Siheng, Liu, Mingyue, Wang, Shu, Zhang, Yingshi

“…Objective. The phosphatidylinositol 3-kinase (PI3K) signaling pathway is a promising treatment target for patients with breast cancer (BC). Our study aimed to…”
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The Modified Bushen Antai Recipe Upregulates Estrogen and Progesterone Receptors at the Maternal-Fetal Interface in Pregnant Rats with Mifepristone-Induced Pregnancy Loss by Zhang, Siwen, Jiang, Qinghua, Jian, Lingyan, Yuan, Zhengwei, Sun, Li, Tan, Jichun

“…Background. The modified Bushen Antai recipe (BSAT) is a centuries-old traditional Chinese medicine that we use in our center as a therapy against pregnancy…”
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Pharmacokinetics, Safety, and Tolerability of Amygdalin and Paeoniflorin After Single and Multiple Intravenous Infusions of Huoxue-Tongluo Lyophilized Powder for Injection in Healthy Chinese Volunteers by Li, Xiaobing, PhD, Shi, Fuguo, PhD, Zhang, Run, MS, Sun, Chenglong, MS, Gong, Chuting, MS, Jian, Lingyan, MS, Ding, Li, PhD

“…Abstract Purpose Huoxue-Tongluo lyophilized powder for injection (HTLPI), a traditional Chinese medicine preparation, is a compound of Persicae semen and…”
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Utilization of PLGA nanoparticles in yeast cell wall particle system for oral targeted delivery of exenatide to improve its hypoglycemic efficacy by Ren, Tianyang, Zheng, Xuehua, Bai, Ruixue, Yang, Yuehui, Jian, Lingyan

“…[Display omitted] Oral delivery of exenatide (EXE), a high-efficiency therapeutic peptide, is urgently needed for long-term treatment of diabetes. In this…”
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Bioadhesive poly(methyl vinyl ether-co-maleic anhydride)-TPGS copolymer modified PLGA/lipid hybrid nanoparticles for improving intestinal absorption of cabazitaxel by Ren, Tianyang, Zheng, Xuehua, Bai, Ruixue, Yang, Yuehui, Jian, Lingyan

“…[Display omitted] A bioadhesive nanocarrier, PTNP, was constructed by utilizing a novel poly(methyl vinyl ether-co-maleic anhydride)- D-α-Tocopheryl…”
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Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF-κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling by Liu, Xiaodong, Tian, Shuo, Liu, Mei, Jian, Lingyan, Zhao, Limei

“…The anticancer effects of the natural flavonoid, wogonin, have been reported. However, its molecular mechanisms of action have not yet been fully explored. In…”
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Evaluating biosimilars: safety, efficacy, and regulatory considerations in clinical studies by Liu, Yuqiang, Wang, Yu, Wang, Minglu, Zhai, Suodi, Hou, Chunxia, Sun, Feng, Jian, Lingyan

“…Biosimilars are a rapidly growing area of clinical research, yet they encounter significant challenges, especially in emerging markets where regulatory and…”
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Behavioral responses of Araecerus fasciculatus (Coleoptera: Anthribidae) to volatiles of selected stored Chinese medicinal plant products by Zeng, Guang, Xie, Songhai, Jian, Lingyan, Agrafioti, Paraskevi, Wu, Kaixian, Athanassiou, Christos G, Cao, Yu

“…The olfactory responses of Araecerus fasciculatus Degeer to the volatiles of 5 traditional Chinese medicine plant products (CMPPs; i.e., Codonopsis pilosula…”
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Reserpine, a novel N6-methyladenosine regulator, reverses Lenvatinib resistance in hepatocellular carcinoma by Zhao, Lei, Ma, Heyao, Jiang, Yuhui, Li, Yingying, Guo, Ning, Chen, Yu, Jiang, Xiaowen, Zhao, Yunpeng, Yang, Jingjing, Liu, Yifei, Wen, Kaishu, Wang, Lihui, Jian, Lingyan, Fan, Xinyu

“…Hepatocellular carcinoma (HCC) is an aggressive malignancy and a growing global health problem. Reserpine (Res), a plant-derived hypertension drug, has been…”
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Anesthetic Propofol Attenuates Apoptosis, Aβ Accumulation, and Inflammation Induced by Sevoflurane Through NF-κB Pathway in Human Neuroglioma Cells by Tian, Yue, Guo, Shanbin, Guo, Yao, Jian, Lingyan

“…Anesthetics have been reported to promote Alzheimer’s disease neuropathogenesis by inducing amyloid beta (Aβ) protein accumulation and apoptosis. The aim of…”
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Behavioral responses of Rhyzopertha dominica (F.) to volatiles of different stored grains by Cao, Yu, Jian, Lingyan, Athanassiou, Christos G., Yang, Yuping, Hu, Qiqi, Zhang, Xueyan, Dai, Fanglian, Maggi, Filippo

“…The aim of this study was to explore the behavioral responses of the lesser grain borer, Rhyzopertha dominica (F.) to volatiles of different stored grains. The…”
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S/O/W microparticles prepared with hydroxyethyl starch-based emulsifier showed reduced macrophage affinity by Li, Qingqing, Fan, Xinyu, Pan, Xiaohan, Yu, Ying, Jian, Lingyan, Zhang, Yu, Yin, Tian, He, Haibing, Tang, Xing, Jin, Jian, Gou, Jingxin

“…The intramuscular administration of long-acting injectable microparticles elicits a local macrophage uptake resulting in decreased bioavailability. Herein, we…”
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Mixed Micelles of Doxorubicin Overcome Multidrug Resistance by Inhibiting the Expression of P-Glycoprotein by Jin, Yan, Zhang, Zhijie, Zhao, Tie, Liu, Xiaodong, Jian, Lingyan

“…With the goal of overcoming multidrug resistance, DSPE-PEG (polyethylene glycol 2000 grafted with distearoyl phosphatidylethanolamine) and TPGS…”
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A rapid and sensitive LC–MS/MS method for determination of lercanidipine in human plasma and its application in a bioequivalence study in Chinese healthy volunteers by Li, Xiaobing, Shi, Fuguo, He, Xiaojing, Jian, Lingyan, Ding, Li

“…[Display omitted] •A novel LC–MS/MS method for determination of LER in human plasma.•Most sensitive method with LLOQ of 0.015ng/mL reported so far.•More simple…”
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Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF-κB/BCI-2, EGFR and EGFR downstream ERK/AKT signaling by Liu, Xiaodong, Tian, Shuo, Liu, Mei, Jian, Lingyan, Zhao, Limei

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Severe hypertriglyceridemia secondary to asparaginase administered to adult patients: report of 2 cases and literature review by Pang, Lu, Liu, Zhuogang, Zhu, Ke, Jian, Lingyan, Zhao, Limei

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