Search Results - "Jian, Dan"

A systematic review of lopinavir therapy for SARS coronavirus and MERS coronavirus—A possible reference for coronavirus disease‐19 treatment option by Yao, Tian‐Tian, Qian, Jian‐Dan, Zhu, Wen‐Yan, Wang, Yan, Wang, Gui‐Qiang

“…In the past few decades, coronaviruses have risen as a global threat to public health. Currently, the outbreak of coronavirus disease‐19 (COVID‐19) from Wuhan…”
Get full text

FUNDC1 inhibits NLRP3-mediated inflammation after intracerebral hemorrhage by promoting mitophagy in mice by Zheng, Shuyue, Jian, Dan, Gan, Hui, Wang, Lu, Zhao, Jing, Zhai, Xuan

“…•The expression of FUNDC1 reached its peak 12 h after ICH.•FUNDC1 siRNA aggravates ICH-induced brain injury, while inhibit mitophagy.•Mitophagy specific…”
Get full text

Kick effect of enzymes causes filament compression by Mao, Dan-Jian, Qin, Chao-Ran, Tian, Wen-de

“…We investigate the influence of enzymes on the structure and dynamics of a filament by dissipative particle dynamics simulations. Enzyme exerts a kick force on…”
Get more information

Epidemiological features of rosacea in Changsha, China: A population‐based, cross‐sectional study by Li, Jinglin, Wang, Ben, Deng, Yuxuan, Shi, Wei, Jian, Dan, Liu, Fangfen, Huang, Yingxue, Tang, Yan, Zhao, Zhixiang, Huang, Xin, Li, Ji, Xie, Hongfu

“…Rosacea is a common chronic skin disorder of unknown etiology. While population prevalence rates range 0.2–22% in Europe and North America, prevalence in China…”
Get full text

Whole genome sequencing identifies genetic variants associated with neurogenic inflammation in rosacea by Deng, Zhili, Chen, Mengting, Zhao, Zhixiang, Xiao, Wenqin, Liu, Tangxiele, Peng, Qinqin, Wu, Zheng, Xu, San, Shi, Wei, Jian, Dan, Wang, Ben, Liu, Fangfen, Tang, Yan, Huang, Yingxue, Zhang, Yiya, Wang, Qian, Sun, Lunquan, Xie, Hongfu, Zhang, Guohong, Li, Ji

“…Rosacea is a chronic inflammatory skin disorder with high incidence rate. Although genetic predisposition to rosacea is suggested by existing evidence, the…”
Get full text

A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea by Deng, Zhili, Chen, Mengting, Liu, Yingzi, Xu, San, Ouyang, Yuyan, Shi, Wei, Jian, Dan, Wang, Ben, Liu, Fangfen, Li, Jinmao, Shi, Qian, Peng, Qinqin, Sha, Ke, Xiao, Wenqin, Liu, Tangxiele, Zhang, Yiya, Zhang, Hongbing, Wang, Qian, Sun, Lunquan, Xie, Hongfu, Li, Ji

“…Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1…”
Get full text

The Rosacea-specific Quality-of-Life instrument (RosQol): Revision and validation among Chinese patients by Deng, Yuxuan, Peng, Qinqin, Yang, Sai, Jian, Dan, Wang, Ben, Huang, Yingxue, Xie, Hongfu, Li, Ji

“…Rosacea is a common chronic facial disorder that affects patients' health-related quality of life; the only questionnaire designed specifically for rosacea is…”
Get full text

Treatment of primary biliary cholangitis with ursodeoxycholic acid, prednisolone and immunosuppressants in patients not responding to ursodeoxycholic acid alone and the prognostic indicators by Qian, Jian-Dan, Yao, Tian-Tian, Wang, Yan, Wang, Gui-Qiang

“…•Therapy combined with UDCA, prednisolone and immunosuppressants is more effectivity than UDCA monotherapy for PBC patients.•The improvements are mainly focus…”
Get full text

Single-cell transcriptomics reveals aberrant skin-resident cell populations and identifies fibroblasts as a determinant in rosacea by Chen, Mengting, Yang, Li, Zhou, Peijie, Jin, Suoqin, Wu, Zheng, Tan, Zixin, Xiao, Wenqin, Xu, San, Zhu, Yan, Wang, Mei, Jian, Dan, Liu, Fangfen, Tang, Yan, Zhao, Zhixiang, Huang, Yingxue, Shi, Wei, Xie, Hongfu, Nie, Qing, Wang, Ben, Deng, Zhili, Li, Ji

“…Rosacea is a chronic inflammatory skin disorder, whose underlying cellular and molecular mechanisms remain obscure. Here, we generate a single-cell atlas of…”
Get full text

Efficacy and safety of single microneedle radiofrequency vs . photodynamic therapy on moderate-to-severe acne vulgaris: A prospective, randomized, controlled study by Huang, Chuchu, Mao, Mengping, Peng, Yiran, Wang, Ben, Deng, Yuxuan, Xie, Hongfu, Jian, Dan

“…A significant reduction in inflammatory lesions was observed after as early as the first session in the MRF group and persisted until the end of the study…”
Get full text

Keratinocyte-Immune Cell Crosstalk in a STAT1-Mediated Pathway: Novel Insights Into Rosacea Pathogenesis by Deng, Zhili, Liu, Fangfen, Chen, Mengting, Huang, Chuchu, Xiao, Wenqin, Gao, Sini, Jian, Dan, Ouyang, Yuyan, Xu, San, Li, Jinmao, Shi, Qian, Xie, Hongfu, Zhang, Guohong, Li, Ji

“…Rosacea is a common chronic inflammatory condition that mainly affects the central face. However, the molecular background of the normal central face and the…”
Get full text

NPAS4 Exacerbates Pyroptosis via Transcriptionally Regulating NLRP6 in the Acute Phase of Intracerebral Hemorrhage in Mice by Jian, Dan, Qin, Le, Gan, Hui, Zheng, Shuyue, Xiao, Han, Duan, Yuhao, Zhang, Mi, Liang, Ping, Zhao, Jing, Zhai, Xuan

“…Intracerebral hemorrhage (ICH) is a severe cerebrovascular disease with a high disability rate and high mortality, and pyroptosis is a type of programmed cell…”
Get full text

Claudin reduction may relate to an impaired skin barrier in rosacea by Deng, Zhili, Chen, Mengting, Xie, Hongfu, Jian, Dan, Xu, San, Peng, Qinqin, Sha, Ke, Liu, Yingzi, Zhang, Yiya, Shi, Wei, Li, Ji

“…Rosacea is a chronic inflammatory skin disorder whose pathophysiological mechanism remains largely unknown. Although recent studies have revealed the…”
Get full text

Identification of four immune subtypes in locally advanced rectal cancer treated with neoadjuvant chemotherapy for predicting the efficacy of subsequent immune checkpoint blockade by He, Le, Jin, Min, Jian, Dan, Yang, Bo, Dai, Nan, Feng, Yan, Xiao, He, Wang, Dong

“…IntroductionNeoadjuvant chemoradiotherapy (nCRT) is the foundation treatment for locally advanced rectal cancer (LARC). The nCRT can improve the efficacy of…”
Get full text

Efficacy of ursodeoxycholic acid combined with prednisolone and immunosuppressant triple therapy in the treatment of refractory primary biliary cholangitis by Yao, Tian-Tian, Qian, Jian-Dan, Wang, Gui-Qiang

“…To explore the efficacy treatment regimen in refractory PBC. Triple treatment including ursodeoxycholic acid, prednisolone and immunosuppressant was prescribed…”
Get more information

Editorial: Physical therapy in the treatment of skin diseases and its mechanism by Hamblin, Michael R., Yin, Rui, Jian, Dan

Get full text

Key protein-coding genes related to microglia in immune regulation and inflammatory response induced by epilepsy by Cao, Jing, Gan, Hui, Xiao, Han, Chen, Hui, Jian, Dan, Jian, Dan, Zhai, Xuan

“…Several studies have shown a link between immunity, inflammatory processes, and epilepsy. Active neuroinflammation and marked immune cell infiltration occur in…”
Get full text

A novel multi-layer perceptron model for assessing the diagnostic value of non-invasive imaging instruments for rosacea by Huang, Yingxue, He, Jieyu, Zhang, Shuping, Tang, Yan, Wang, Ben, Jian, Dan, Xie, Hongfu, Li, Ji, Chen, Feng, Zhao, Zhixiang

“…Reflectance confocal microscopy (RCM), VISIA, and dermoscopy have emerged as promising tools for objective diagnosis and assessment of rosacea. However, little…”
Get full text

Gilbert syndrome combined with prolonged jaundice caused by contrast agent: Case report by Qian, Jian-Dan, Hou, Feng-Qin, Wang, Tai-Ling, Shao, Chen, Wang, Gui-Qiang

“…This case highlights a patient with Gilbert syndrome who underwent endoscopic retrograde cholangiopancreatography (ERCP) with removal of bile duct stones, who…”
Get full text

Formulation, characterization and clinical evaluation of propranolol hydrochloride gel for transdermal treatment of superficial infantile hemangioma by Zhou, Wenhu, He, Shiying, Yang, Yijun, Jian, Dan, Chen, Xiang, Ding, Jinsong

“…Abstract The objective of the present study is to formulate and characterize propranolol hydrochloride (PPL   HCl) gel, and to evaluate the efficacy of this…”
Get full text