Search Results - "Jia, Yousheng"

Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases by Le, Aliza A., Lauterborn, Julie C., Jia, Yousheng, Wang, Weisheng, Cox, Conor D., Gall, Christine M., Lynch, Gary

“…Multiple studies indicate that adult male rodents perform better than females on spatial problems and have a lower threshold for long-term potentiation (LTP)…”
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Chemically Induced Specification of Retinal Ganglion Cells From Human Embryonic and Induced Pluripotent Stem Cells by Riazifar, Hamidreza, Jia, Yousheng, Chen, Jing, Lynch, Gary, Huang, Taosheng

“…In this study, a novel, stepwise chemical protocol is described for the differentiation of human embryonic stem cells and induced pluripotent stem cells into…”
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UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity by Sun, Jiandong, Liu, Yan, Jia, Yousheng, Hao, Xiaoning, Lin, Wei Ju, Tran, Jennifer, Lynch, Gary, Baudry, Michel, Bi, Xiaoning

“…Accumulating evidence indicates that the lysosomal Ragulator complex is essential for full activation of the mechanistic target of rapamycin complex 1…”
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The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory by Vogel-Ciernia, Annie, Matheos, Dina P, Barrett, Ruth M, Kramár, Enikö A, Azzawi, Soraya, Chen, Yuncai, Magnan, Christophe N, Zeller, Michael, Sylvain, Angelina, Haettig, Jakob, Jia, Yousheng, Tran, Anthony, Dang, Richard, Post, Rebecca J, Chabrier, Meredith, Babayan, Alex H, Wu, Jiang I, Crabtree, Gerald R, Baldi, Pierre, Baram, Tallie Z, Lynch, Gary, Wood, Marcelo A

“…BAF53b is a neuron-specific component of the nucleosome remodeling complex mSWI/SNF that allows euchromatin formation and provides epigenetic regulation of…”
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Myosin IIb Regulates Actin Dynamics during Synaptic Plasticity and Memory Formation by Rex, Christopher S., Gavin, Cristin F., Rubio, Maria D., Kramar, Eniko A., Chen, Lulu Y., Jia, Yousheng, Huganir, Richard L., Muzyczka, Nicholas, Gall, Christine M., Miller, Courtney A., Lynch, Gary, Rumbaugh, Gavin

“…Reorganization of the actin cytoskeleton is essential for synaptic plasticity and memory formation. Presently, the mechanisms that trigger actin dynamics…”
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Patch clamp-assisted single neuron lipidomics by Merrill, Collin B., Basit, Abdul, Armirotti, Andrea, Jia, Yousheng, Gall, Christine M., Lynch, Gary, Piomelli, Daniele

“…Our understanding of the physiological and pathological functions of brain lipids is limited by the inability to analyze these molecules at cellular…”
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Brain-Derived Neurotrophic Factor Restores Synaptic Plasticity in a Knock-In Mouse Model of Huntington's Disease by Lynch, Gary, Kramar, Eniko A, Rex, Christopher S, Jia, Yousheng, Chappas, Danielle, Gall, Christine M, Simmons, Danielle A

“…Asymptomatic Huntington's disease (HD) patients exhibit memory and cognition deficits that generally worsen with age. Similarly, long-term potentiation (LTP),…”
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α2 Nicotine receptors function as a molecular switch to continuously excite a subset of interneurons in rat hippocampal circuits by Jia, Yousheng, Yamazaki, Yoshihiko, Nakauchi, Sakura, Sumikawa, Katumi

“…Rapid activation of nicotinic acetylcholine receptors (nAChRs) at various anatomical and cellular locations in the hippocampus differentially modulates the…”
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A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation by Wang, Weisheng, Trieu, Brian H, Palmer, Linda C, Jia, Yousheng, Pham, Danielle T, Jung, Kwang-Mook, Karsten, Carley A, Merrill, Collin B, Mackie, Ken, Gall, Christine M, Piomelli, Daniele, Lynch, Gary

“…The endocannabinoid 2-arachidonoyl-sn-glycerol (2-AG), a key modulator of synaptic transmission in mammalian brain, is produced in dendritic spines and then…”
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Nicotine exposure in vivo induces long-lasting enhancement of NMDA receptor-mediated currents in the hippocampus by Yamazaki, Yoshihiko, Jia, Yousheng, Niu, Rong, Sumikawa, Katumi

“…The use of nicotine via cigarette smoking forms long‐lasting memories that are recalled in response to environmental cues associated with previous nicotine…”
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Programmed alterations in hypothalamic neuronal orexigenic responses to ghrelin following gestational nutrient restriction by Yousheng Jia, Nguyen, Tri, Desai, Mina, Ross, Michael G

“…Intrauterine growth restricted (IUGR) offspring exhibit increased appetite and a propensity to adult obesity. Although the rate of newborn catch-up growth may…”
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Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction by Yamazaki, Yoshihiko, Jia, Yousheng, Hamaue, Naoya, Sumikawa, Katumi

“…Nicotine facilitates the induction of long‐term potentiation (LTP) in the hippocampal CA1 region. The present study reveals the potential mechanisms underlying…”
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Long-term potentiation is impaired in rat hippocampal slices that produce spontaneous sharp waves by Colgin, Laura Lee, Kubota, Don, Jia, Yousheng, Rex, Christopher S., Lynch, Gary

“…Sharp waves (SPWs) occur in the hippocampal EEG during behaviours such as alert immobility and slow-wave sleep. Despite their widespread occurrence across…”
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Nicotine withdrawal suppresses nicotinic modulation of long-term potentiation induction in the hippocampal CA1 region by Yamazaki, Yoshihiko, Fujii, Satoshi, Jia, Yousheng, Sumikawa, Katumi

“…We have previously reported that acute and chronic nicotine exposure lower the threshold for long‐term potentiation (LTP) induction in the rat hippocampal CA1…”
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Blockade of NMDA receptors enhances spontaneous sharp waves in rat hippocampal slices by Colgin, Laura Lee, Jia, Yousheng, Sabatier, Jean-Marc, Lynch, Gary

“…An in vitro model of sharp waves (SPWs) and ripples was used to investigate the involvement of NMDA receptors in SPW/ripple production. Intracellular…”
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Zn2+ currents are mediated by calcium-permeable AMPA/Kainate channels in cultured murine hippocampal neurones by Jia, Yousheng, Jeng, Jade‐Ming, Sensi, Stefano L., Weiss, John H.

“…Permeation of the endogenous cation Zn 2+ through calcium-permeable AMPA/kainate receptor-gated (Ca-A/K) channels might subserve pathological and/or…”
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Nicotine facilitates long-term potentiation induction in oriens-lacunosum moleculare cells via Ca2+ entry through non-α7 nicotinic acetylcholine receptors by Jia, Yousheng, Yamazaki, Yoshihiko, Nakauchi, Sakura, Ito, Ken-Ichi, Sumikawa, Katumi

“…Hippocampal inhibitory interneurons have a central role in the control of network activity, and excitatory synapses that they receive express Hebbian and…”
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Origins of an intrinsic hippocampal EEG pattern by Rex, Christopher S, Colgin, Laura L, Jia, Yousheng, Casale, Malcolm, Yanagihara, Theodore K, Debenedetti, Maria, Gall, Christine M, Kramar, Eniko A, Lynch, Gary

“…Sharp waves (SPWs) are irregular waves that originate in field CA3 and spread throughout the hippocampus when animals are alert but immobile or as a component…”
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Chronic nicotine-induced switch in Src-family kinase signaling for long-term potentiation induction in hippocampal CA1 pyramidal cells by Yamazaki, Yoshihiko, Jia, Yousheng, Wong, Jamie K., Sumikawa, Katumi

“…Here, we show that chronic nicotine exposure induces changes in Src signaling for the modulation of N‐methyl‐d‐aspartate receptor (NMDAR) function and LTP…”
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Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region by Fujii, Satoshi, Jia, Yousheng, Yang, Aizhen, Sumikawa, Katumi

“…Nicotine is known to enhance cognitive function but the mechanism is unknown. The present study examined the modulatory effect of nicotine on the induction of…”
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