Search Results - "Jia, Yingli"
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Propofol Prevents Renal Ischemia-Reperfusion Injury via Inhibiting the Oxidative Stress Pathways
Published in Cellular physiology and biochemistry (01-01-2015)“…Background/Aims: Renal ischemia/reperfusion injury (IRI) is a risk for acute renal failure and delayed graft function in renal transplantation and cardiac…”
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Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice
Published in Frontiers in pharmacology (19-08-2022)“…Nonalcoholic fatty liver disease (NAFLD), which is the most common liver disease, is associated with type 2 diabetes mellitus and metabolic syndrome. Although…”
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Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload
Published in Scientific reports (22-08-2016)“…Albuminuria is a causative and aggravating factor for progressive renal damage in chronic kidney disease (CKD). The aim of this study was to determine if low…”
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Dapagliflozin Aggravates Renal Injury via Promoting Gluconeogenesis in db/db Mice
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: A sodium-glucose co-transporter-2 inhibitor dapagliflozin is widely used for lowering blood glucose and its usage is limited in type 2…”
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Ganoderma triterpenes Protect Against Hyperhomocysteinemia Induced Endothelial-Mesenchymal Transition via TGF-β Signaling Inhibition
Published in Frontiers in physiology (2019)“…Endothelial dysfunction is one of the most important pathological status in hyperhomocysteinemia (HHcy) related cardiovascular diseases. Whereas, the…”
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Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease
Published in Translational research : the journal of laboratory and clinical medicine (01-04-2024)“…Diabetic lipo-toxicity is a fundamental pathophysiologic mechanism in DM and is now increasingly recognized a key determinant of DKD. Targeting lipid metabolic…”
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A new ankylosaurid dinosaur from the Upper Cretaceous of Jiangxi Province, southern China
Published in Historical biology (08-11-2024)Get full text
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Aquaporin‐3 deficiency slows cyst enlargement in experimental mouse models of autosomal dominant polycystic kidney disease
Published in The FASEB journal (01-05-2019)“…ABSTRACTHuman autosomal dominant polycystic kidney disease (ADPKD) is characterized by bilateral renal cysts that lead to a decline in kidney function…”
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Ganoderma triterpenes retard renal cyst development by downregulating Ras/MAPK signaling and promoting cell differentiation
Published in Kidney international (01-12-2017)“…Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disease characterized by the progressive development of renal cysts with further…”
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Baicalein decreases uric acid and prevents hyperuricemic nephropathy in mice
Published in Oncotarget (20-06-2017)“…Baicalein, a natural flavonoid, is structurally advantageous for binding to xanthine oxidoreductase. In our study, molecular docking analysis and Surface…”
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Function and therapeutic potential of G protein‐coupled receptors in epididymis
Published in British journal of pharmacology (01-12-2020)“…Infertility rates for both females and males have increased continuously in recent years. Currently, effective treatments for male infertility with defined…”
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Aquaporin-3 deletion in mice results in renal collecting duct abnormalities and worsens ischemia-reperfusion injury
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2017)“…Aquaporin-3 (AQP3), a transporter of water, glycerol and H2O2, is expressed in basolateral membranes of principal cells in kidney collecting duct. Here, we…”
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Inhibiting Focal Adhesion Kinase Ameliorates Cyst Development in Polycystin-1-Deficient Polycystic Kidney Disease in Animal Model
Published in Journal of the American Society of Nephrology (01-09-2021)“…Autosomal dominant polycystic kidney disease (ADPKD) is characterized by numerous cysts originating from renal tubules and is associated with significant…”
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Low molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes
Published in American journal of translational research (01-01-2015)“…Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes and may lead to end-stage renal disease (ESRD) and chronic renal…”
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Cell active and functionally-relevant small-molecule agonists of calcitonin receptor
Published in Bioorganic chemistry (01-03-2020)“…[Display omitted] •Analogues of SUN-B8155 induced different Gs or arrestin activities through CTR.•N-Hydroxyl group from the pyridone ring is required for G…”
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Functional inhibition of urea transporter UT-B enhances endothelial-dependent vasodilatation and lowers blood pressure via L-arginine-endothelial nitric oxide synthase-nitric oxide pathway
Published in Scientific reports (07-01-2016)“…Mammalian urea transporters (UTs), UT-A and UT-B, are best known for their role in urine concentration. UT-B is especially distributed in multiple extrarenal…”
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Down-regulation of αGal epitopes by co-transfection of α1,3-galactosidase gene and α1,2-fucosyltransferase gene
Published in Science bulletin (Beijing) (01-12-2005)“…The polycarbohydrate structure of Galα1-3Galβ1-4GluNAc-R (known as αGal epitopes of xenoantigen), produced by α1-3-galactosyltransferase (α1,3-GT) in the…”
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