Search Results - "Jia, Qitao"
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Recent Developments of Gramine: Chemistry and Biological Activity
Published in Molecules (Basel, Switzerland) (27-07-2023)“…The natural alkaloid gramine has attracted significant attention in both academic and industrial circles because of its potential and diverse biological…”
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Pilot study of large-scale production of mutant pigs by ENU mutagenesis
Published in eLife (22-06-2017)“…N-ethyl-N-nitrosourea (ENU) mutagenesis is a powerful tool to generate mutants on a large scale efficiently, and to discover genes with novel functions at the…”
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3
Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis
Published in Human genetics (01-11-2017)“…Human Waardenburg syndrome 2A (WS2A) is a dominant hearing loss (HL) syndrome caused by mutations in the microphthalmia-associated transcription factor ( MITF…”
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An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs
Published in Disease models & mechanisms (01-01-2019)“…Pigs share many similarities with humans in terms of anatomy, physiology and genetics, and have long been recognized as important experimental animals in…”
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MetaFluAD: meta-learning for predicting antigenic distances among influenza viruses
Published in Briefings in bioinformatics (25-07-2024)“…Abstract Influenza viruses rapidly evolve to evade previously acquired human immunity. Maintaining vaccine efficacy necessitates continuous monitoring of…”
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Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2017)“…Uncoupling protein 1 (UCP1) is localized on the inner mitochondrial membrane and generates heat by uncoupling ATP synthesis from proton transit across the…”
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Key processes in tumor metastasis and therapeutic strategies with nanocarriers: a review
Published in Molecular biology reports (01-12-2024)“…Cancer metastasis is the leading cause of cancer-related death. Metastasis occurs at all stages of tumor development, with unexplored changes occurring at the…”
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Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis
Published in Blood (16-11-2017)“…Congenital hypothyroidism (CH) is one of the most prevalent endocrine diseases, for which the underlying mechanisms remain unknown; it is often accompanied by…”
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Dysregulation of genome-wide gene expression and DNA methylation in abnormal cloned piglets
Published in BMC genomics (24-09-2014)“…Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development failure or abnormalities…”
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A harlequin ichthyosis pig model with a novel ABCA12 mutation can be rescued by acitretin treatment
Published in Journal of molecular cell biology (19-12-2019)“…Harlequin ichthyosis (HI) is a severe genetic skin disorder and caused by mutation in the ATP-binding cassette A12 (ABCA12) gene. The retinoid administration…”
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A 2-bp insertion (c.67_68insCC) in MC1R causes recessive white coat color in Bama miniature pigs
Published in Journal of genetics and genomics (20-04-2017)Get full text
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A 2-bp insertion(c.6768insCC) in MC1R causes recessive white coat color in Bama miniature pigs
Published in 遗传学报:英文版 (2017)“…Coat color is an important characteristic of various breeds of domestic animal species.Variation in farm animal coat color is of considerable interest for…”
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