Search Results - "Jia, Hangxing"
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The energy-rush and insulin model of obesity
Published in Research Ideas and Outcomes (09-08-2023)“…Obesity has been a global health problem since the twentieth century. Despite the intensive research, there is no scientific consensus on the onset of obesity…”
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Low-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes
Published in Nature communications (05-07-2024)“…Long-read sequencing, exemplified by PacBio, revolutionizes genomics, overcoming challenges like repetitive sequences. However, the high DNA requirement ( > 1…”
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Genomic analyses of new genes and their phenotypic effects reveal rapid evolution of essential functions in Drosophila development
Published in PLoS genetics (09-07-2021)“…It is a conventionally held dogma that the genetic basis underlying development is conserved in a long evolutionary time scale. Ample experiments based on…”
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Chasing Sequencing Perfection: Marching Toward Higher Accuracy and Lower Costs
Published in Genomics, proteomics & bioinformatics (03-07-2024)“…Next-generation sequencing (NGS), represented by Illumina platforms, has been an essential cornerstone of basic and applied research. However, the sequencing…”
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LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans
Published in Genome research (01-12-2016)“…In a broad range of taxa, genes can duplicate through an RNA intermediate in a process mediated by retrotransposons (retroposition). In mammals, L1…”
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Multistage Regulator Based on Tandem Promoters and CRISPR/Cas
Published in ACS synthetic biology (19-12-2014)“…Accurately controlling expression of target genes between several designed levels is essential for low-noise gene network and dynamic range of gene expression…”
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