Search Results - "Jia, Danna"

Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration by Liu, Fei, Qin, Yayun, Huang, Yuwen, Gao, Pan, Li, Jingzhen, Yu, Shanshan, Jia, Danna, Chen, Xiang, Lv, Yuexia, Tu, Jiayi, Sun, Kui, Han, Yunqiao, Reilly, James, Shu, Xinhua, Lu, Qunwei, Tang, Zhaohui, Xu, Chengqi, Luo, Daji, Liu, Mugen

“…Neural retina leucine zipper (NRL) is an essential gene for the fate determination and differentiation of the precursor cells into rod photoreceptors in…”
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Differentially Expressed Genes in Atopic Dermatitis: Bioinformatics analysis of pooled microarray gene expression datasets in Gene Expression Omnibus by Jia, Danna, Chen, Wenqiang, Li, Bin

“…Introduction: Atopic dermatitis (AD) is a chronic and refractory inflammatory skin disease characterized by relapsing eczematous and pruritic skin lesions…”
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Deletion of the transmembrane protein Prom1b in zebrafish disrupts outer-segment morphogenesis and causes photoreceptor degeneration by Lu, Zhaojing, Hu, Xuebin, Reilly, James, Jia, Danna, Liu, Fei, Yu, Shanshan, Liu, Xiliang, Xie, Shanglun, Qu, Zhen, Qin, Yayun, Huang, Yuwen, Lv, Yuexia, Li, Jingzhen, Gao, Pan, Wong, Fulton, Shu, Xinhua, Tang, Zhaohui, Liu, Mugen

“…Mutations in human prominin 1 (PROM1), encoding a transmembrane glycoprotein localized mainly to plasma membrane protrusions, have been reported to cause…”
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Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish by Jia, Danna, Gao, Pan, Lv, Yuexia, Huang, Yuwen, Reilly, James, Sun, Kui, Han, Yunqiao, Hu, Hualei, Chen, Xiang, Zhang, Zuxiao, Li, Pei, Luo, Jiong, Shu, Xinhua, Tang, Zhaohui, Liu, Fei, Liu, Mugen, Ren, Xiang

“…Mutations in TUB-like protein 1 ( TULP1 ) are associated with severe early-onset retinal degeneration in humans. However, the pathogenesis remains largely…”
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Cross-species single-cell landscapes identify the pathogenic gene characteristics of inherited retinal diseases by Hu, Hualei, Liu, Fei, Gao, Pan, Huang, Yuwen, Jia, Danna, Reilly, Jamas, Chen, Xiang, Han, Yunqiao, Sun, Kui, Luo, Jiong, Li, Pei, Zhang, Zuxiao, Wang, Qing, Lu, Qunwei, Luo, Daji, Shu, Xinhua, Tang, Zhaohui, Liu, Mugen, Ren, Xiang

“…Inherited retinal diseases (IRDs) affect ∼4.5 million people worldwide. Elusive pathogenic variants in over 280 genes are associated with one or more clinical…”
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Retinal degeneration in rpgra mutant zebrafish by Liu, Xiliang, Han, Shanshan, Liu, Fei, Yu, Shanshan, Qin, Yayun, Li, Jingzhen, Jia, Danna, Gao, Pan, Chen, Xiang, Tang, Zhaohui, Liu, Mugen, Huang, Yuwen

“…Pathogenic mutations in , one of two major human isoforms, were responsible for most X-linked retinitis pigmentosa cases. Previous studies have shown that…”
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The splicing factor DHX38 enables retinal development through safeguarding genome integrity by Sun, Kui, Han, Yunqiao, Li, Jingzhen, Yu, Shanshan, Huang, Yuwen, Zhang, Yangjun, Reilly, Jamas, Tu, Jiayi, Gao, Pan, Jia, Danna, Chen, Xiang, Hu, Hualei, Ren, Mengmeng, Li, Pei, Luo, Jiong, Ren, Xiang, Zhang, Xianqin, Shu, Xinhua, Liu, Fei, Liu, Mugen, Tang, Zhaohui

“…DEAH-Box Helicase 38 (DHX38) is a pre-mRNA splicing factor and also a disease-causing gene of autosomal recessive retinitis pigmentosa (arRP). The role of…”
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Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells by Chen, Xiang, Huang, Yuwen, Gao, Pan, Lv, Yuexia, Jia, Danna, Sun, Kui, Han, Yunqiao, Hu, Hualei, Tang, Zhaohui, Ren, Xiang, Liu, Mugen

“…Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the…”
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IFT27 regulates the long-term maintenance of photoreceptor outer segments in zebrafish by Han, Shanshan, Hu, Yue, Jia, Danna, Lv, Yuexia, Liu, Mugen, Wang, Decheng, Chao, Jin, Xia, Xuan, Wang, Qiong, Liu, Pei, Cai, Yu, Ren, Xiang

“…•Ablation of ift27 in zebrafish leads to progressive late-onset photoreceptor degeneration.•Rods degenerate before cones in ift27-/- zebrafish.•IFT27 is…”
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Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing by Li, Jingzhen, Liu, Fei, Lv, Yuexia, Sun, Kui, Zhao, Yuntong, Reilly, Jamas, Zhang, Yangjun, Tu, Jiayi, Yu, Shanshan, Liu, Xiliang, Qin, Yayun, Huang, Yuwen, Gao, Pan, Jia, Danna, Chen, Xiang, Han, Yunqiao, Shu, Xinhua, Luo, Daji, Tang, Zhaohui, Liu, Mugen

“…Abstract Dysfunction of splicing factors often result in abnormal cell differentiation and apoptosis, especially in neural tissues. Mutations in pre-mRNAs…”
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CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1 by Hu, Xuebin, Lu, Zhaojing, Yu, Shanshan, Reilly, James, Liu, Fei, Jia, Danna, Qin, Yayun, Han, Shanshan, Liu, Xiliang, Qu, Zhen, Lv, Yuexia, Li, Jingzhen, Huang, Yuwen, Jiang, Tao, Jia, Haibo, Wang, Qing, Liu, Jingyu, Shu, Xinhua, Tang, Zhaohui, Liu, Mugen

“…Macroautophagy/autophagy is an important intracellular mechanism for the maintenance of cellular homeostasis. Here we show that the CERKL (ceramide kinase…”
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Accumulation of Lipid Droplets in a Novel Bietti Crystalline Dystrophy Zebrafish Model With Impaired PPARα Pathway by Gao, Pan, Jia, Danna, Li, Pei, Huang, Yuwen, Hu, Hualei, Sun, Kui, Lv, Yuexia, Chen, Xiang, Han, Yunqiao, Zhang, Zuxiao, Ren, Xiang, Wang, Qing, Liu, Fei, Tang, Zhaohui, Liu, Mugen

“…Bietti crystalline dystrophy (BCD) is a progressive retinal degenerative disease primarily characterized by numerous crystal-like deposits and degeneration of…”
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The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis by Lv, Yuexia, Li, Jingzhen, Yu, Shanshan, Zhang, Yangjun, Hu, Hualei, Sun, Kui, Jia, Danna, Han, Yunqiao, Tu, Jiayi, Huang, Yuwen, Liu, Xiliang, Zhang, Xianghan, Gao, Pan, Chen, Xiang, Shaw Williams, Mark Thomas, Tang, Zhaohui, Shu, Xinhua, Liu, Mugen, Ren, Xiang

“…Pre-mRNA splicing is a precise regulated process and is crucial for system development and homeostasis maintenance. Mutations in spliceosomal components have…”
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A large deletion spanning PITX2 and PANCR in a Chinese family with Axenfeld-Rieger syndrome by Qin, Yayun, Gao, Pang, Yu, Shanshan, Li, Jingzhen, Huang, Yuwen, Jia, Danna, Tang, Zhaohui, Li, Pengcheng, Liu, Fei, Liu, Mugen

“…To identify the genetic cause in a four-generation Chinese family with Axenfeld-Rieger syndrome (ARS). The family members received clinical examinations of the…”
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BCAS2 is essential for hematopoietic stem and progenitor cell maintenance during zebrafish embryogenesis by Yu, Shanshan, Jiang, Tao, Jia, Danna, Han, Yunqiao, Liu, Fei, Huang, Yuwen, Qu, Zhen, Zhao, Yuntong, Tu, Jiayi, Lv, Yuexia, Li, Jingzhen, Hu, Xuebin, Lu, Zhaojing, Han, Shanshan, Qin, Yayun, Liu, Xiliang, Xie, Shanglun, Wang, Qing K., Tang, Zhaohui, Luo, Daji, Liu, Mugen

“…Hematopoietic stem and progenitor cells (HSPCs) originate from the hemogenic endothelium via the endothelial-to-hematopoietic transition, are self-renewing,…”
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Reply to Corbeil et al.: Deletion of the transmembrane protein Prom1b in zebrafish disrupts outer-segment morphogenesis and causes photoreceptor degeneration by Lu, Zhaojing, Hu, Xuebin, Reilly, James, Jia, Danna, Liu, Fei, Yu, Shanshan, Liu, Xiliang, Xie, Shanglun, Qu, Zhen, Qin, Yayun, Huang, Yuwen, Lv, Yuexia, Li, Jingzhen, Gao, Pan, Wong, Fulton, Shu, Xinhua, Tang, Zhaohui, Liu, Mugen

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