Search Results - "Ji, Zhaoxia"

Use of compositional and combinatorial nanomaterial libraries for biological studies by Ji, Zhaoxia

“…Abstract The rapid development and production of nanomaterials has created some concerns about their potential hazard on the environment, human health and…”
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Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening by Nel, Andre, Xia, Tian, Meng, Huan, Wang, Xiang, Lin, Sijie, Ji, Zhaoxia, Zhang, Haiyuan

“…The production of engineered nanomaterials (ENMs) is a sci-entific breakthrough in material design and the development of new consumer products. While the…”
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NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials by Sun, Bingbing, Wang, Xiang, Ji, Zhaoxia, Li, Ruibin, Xia, Tian

“…Engineered nanomaterials (ENMs) continue to attract significant attention because they have novel physicochemical properties that can improve the functions of…”
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Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice by Meng, Huan, Wang, Meiying, Liu, Huiyu, Liu, Xiangsheng, Situ, Allen, Wu, Bobby, Ji, Zhaoxia, Chang, Chong Hyun, Nel, Andre E

“…Recently, a commercial albumin-bound paclitaxel (PTX) nanocarrier (Abraxane) was approved as the first new drug for pancreatic ductal adenocarcinoma in almost…”
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Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line by Meng, Huan, Liong, Monty, Xia, Tian, Li, Zongxi, Ji, Zhaoxia, Zink, Jeffrey I, Nel, Andre E

“…Overexpression of drug efflux transporters such as P-glycoprotein (Pgp) protein is one of the major mechanisms for multiple drug resistance (MDR) in cancer…”
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Codelivery of an Optimal Drug/siRNA Combination Using Mesoporous Silica Nanoparticles To Overcome Drug Resistance in Breast Cancer in Vitro and in Vivo by Meng, Huan, Mai, Wilson X, Zhang, Haiyuan, Xue, Min, Xia, Tian, Lin, Sijie, Wang, Xiang, Zhao, Yang, Ji, Zhaoxia, Zink, Jeffrey I, Nel, Andre E

“…We used a multifunctional mesoporous silica nanoparticle (MSNP) carrier to overcome doxorubicin (Dox) resistance in a multidrug resistant (MDR) human breast…”
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Toxicity Mechanisms in Escherichia coli Vary for Silver Nanoparticles and Differ from Ionic Silver by Ivask, Angela, ElBadawy, Amro, Kaweeteerawat, Chitrada, Boren, David, Fischer, Heidi, Ji, Zhaoxia, Chang, Chong Hyun, Liu, Rong, Tolaymat, Thabet, Telesca, Donatello, Zink, Jeffrey I, Cohen, Yoram, Holden, Patricia Ann, Godwin, Hilary A

“…Silver nanoparticles (Ag NPs) are commonly added to various consumer products and materials to impair bacterial growth. Recent studies suggested that the…”
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Multi-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces by Cai, Xiaoming, Dong, Jun, Liu, Jing, Zheng, Huizhen, Kaweeteerawat, Chitrada, Wang, Fangjun, Ji, Zhaoxia, Li, Ruibin

“…Increasing concerns over the possible risks of nanotechnology necessitates breakthroughs in structure–activity relationship (SAR) analyses of engineered…”
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Stability and Aggregation of Metal Oxide Nanoparticles in Natural Aqueous Matrices by Keller, Arturo A, Wang, Hongtao, Zhou, Dongxu, Lenihan, Hunter S, Cherr, Gary, Cardinale, Bradley J, Miller, Robert, Ji, Zhaoxia

“…There is a pressing need for information on the mobility of nanoparticles in the complex aqueous matrices found in realistic environmental conditions. We…”
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Identification and Optimization of Carbon Radicals on Hydrated Graphene Oxide for Ubiquitous Antibacterial Coatings by Li, Ruibin, Mansukhani, Nikhita D, Guiney, Linda M, Ji, Zhaoxia, Zhao, Yichao, Chang, Chong Hyun, French, Christopher T, Miller, Jeff F, Hersam, Mark C, Nel, Andre E, Xia, Tian

“…While the antibacterial properties of graphene oxide (GO) have been demonstrated across a spectrum of bacteria, the critical role of functional groups is…”
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High Content Screening in Zebrafish Speeds up Hazard Ranking of Transition Metal Oxide Nanoparticles by Lin, Sijie, Zhao, Yan, Xia, Tian, Meng, Huan, Ji, Zhaoxia, Liu, Rong, George, Saji, Xiong, Sijing, Wang, Xiang, Zhang, Haiyuan, Pokhrel, Suman, Mädler, Lutz, Damoiseaux, Robert, Lin, Shuo, Nel, Andre E

“…Zebrafish is an aquatic organism that can be used for high content safety screening of engineered nanomaterials (ENMs). We demonstrate, for the first time, the…”
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Use of Size and a Copolymer Design Feature To Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-Loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model by Meng, Huan, Xue, Min, Xia, Tian, Ji, Zhaoxia, Tarn, Derrick Y, Zink, Jeffrey I, Nel, Andre E

“…A key challenge for improving the efficacy of passive drug delivery to tumor sites by a nanocarrier is to limit reticuloendothelial system uptake and to…”
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Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation by Zhang, Haiyuan, Ji, Zhaoxia, Xia, Tian, Meng, Huan, Low-Kam, Cecile, Liu, Rong, Pokhrel, Suman, Lin, Sijie, Wang, Xiang, Liao, Yu-Pei, Wang, Meiying, Li, Linjiang, Rallo, Robert, Damoiseaux, Robert, Telesca, Donatello, Mädler, Lutz, Cohen, Yoram, Zink, Jeffrey I, Nel, Andre E

“…We demonstrate for 24 metal oxide (MOx) nanoparticles that it is possible to use conduction band energy levels to delineate their toxicological potential at…”
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Designed Synthesis of CeO2 Nanorods and Nanowires for Studying Toxicological Effects of High Aspect Ratio Nanomaterials by Ji, Zhaoxia, Wang, Xiang, Zhang, Haiyuan, Lin, Sijie, Meng, Huan, Sun, Bingbing, George, Saji, Xia, Tian, Nel, André E, Zink, Jeffrey I

“…While it has been shown that high aspect ratio nanomaterials like carbon nanotubes and TiO2 nanowires can induce toxicity by acting as fiber-like substances…”
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Role of Fe Doping in Tuning the Band Gap of TiO2 for the Photo-Oxidation-Induced Cytotoxicity Paradigm by George, Saji, Pokhrel, Suman, Ji, Zhaoxia, Henderson, Bryana L, Xia, Tian, Li, LinJiang, Zink, Jeffrey I, Nel, André E, Mädler, Lutz

“…UV-light-induced electron–hole (e–/h+) pair generation with free radical production in TiO2-based nanoparticles is a major conceptual paradigm for biological…”
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Aspect Ratio Determines the Quantity of Mesoporous Silica Nanoparticle Uptake by a Small GTPase-Dependent Macropinocytosis Mechanism by Meng, Huan, Yang, Sui, Li, Zongxi, Xia, Tian, Chen, Justin, Ji, Zhaoxia, Zhang, Haiyuan, Wang, Xiang, Lin, Sijie, Huang, Connie, Zhou, Z. Hong, Zink, Jeffrey I, Nel, Andre E

“…Although the aspect ratio (AR) of engineered nanomaterials (ENMs) is one of the key physicochemical parameters that could determine biological outcome, not…”
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Processing Pathway Dependence of Amorphous Silica Nanoparticle Toxicity: Colloidal vs Pyrolytic by Zhang, Haiyuan, Dunphy, Darren R, Jiang, Xingmao, Meng, Huan, Sun, Bingbing, Tarn, Derrick, Xue, Min, Wang, Xiang, Lin, Sijie, Ji, Zhaoxia, Li, Ruibin, Garcia, Fred L, Yang, Jing, Kirk, Martin L, Xia, Tian, Zink, Jeffrey I, Nel, Andre, Brinker, C. Jeffrey

“…We have developed structure/toxicity relationships for amorphous silica nanoparticles (NPs) synthesized through low-temperature colloidal (e.g., Stöber…”
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Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential by Wang, Xiang, Ji, Zhaoxia, Chang, Chong Hyun, Zhang, Haiyuan, Wang, Meiying, Liao, Yu-Pei, Lin, Sijie, Meng, Huan, Li, Ruibin, Sun, Bingbing, Winkle, Laura Van, Pinkerton, Kent E., Zink, Jeffrey I., Xia, Tian, Nel, André E.

“…Since more than 30% of consumer products that include engineered nanomaterials contain nano‐Ag, the safety of this material is of considerable public concern…”
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Surface Charge and Cellular Processing of Covalently Functionalized Multiwall Carbon Nanotubes Determine Pulmonary Toxicity by Li, Ruibin, Wang, Xiang, Ji, Zhaoxia, Sun, Bingbing, Zhang, Haiyuan, Chang, Chong Hyun, Lin, Sijie, Meng, Huan, Liao, Yu-Pei, Wang, Meiying, Li, Zongxi, Hwang, Angela A, Song, Tze-Bin, Xu, Run, Yang, Yang, Zink, Jeffrey I, Nel, André E, Xia, Tian

“…Functionalized carbon nanotubes (f-CNTs) are being produced in increased volume because of the ease of dispersion and maintenance of the pristine material…”
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Influence of material properties on TiO2 nanoparticle agglomeration by Zhou, Dongxu, Ji, Zhaoxia, Jiang, Xingmao, Dunphy, Darren R, Brinker, Jeffrey, Keller, Arturo A

“…Emerging nanomaterials are being manufactured with varying particle sizes, morphologies, and crystal structures in the pursuit of achieving outstanding…”
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