Search Results - "Ji, Yingbiao"

The roles of PARP1 in gene control and cell differentiation by Ji, Yingbiao, Tulin, Alexei V

“…Cell growth and differentiation during developmental processes require the activation of many inducible genes. However, eukaryotic chromatin, which consists of…”
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Hit and run versus long-term activation of PARP-1 by its different domains fine-tunes nuclear processes by Thomas, Colin, Ji, Yingbiao, Wu, Chao, Datz, Haily, Boyle, Cody, MacLeod, Brett, Patel, Shri, Ampofo, Michelle, Currie, Michelle, Harbin, Jonathan, Pechenkina, Kate, Lodhi, Niraj, Johnson, Sarah J., Tulin, Alexei V.

“…Poly(ADP-ribose) polymerase 1 (PARP-1) is a multidomain multifunctional nuclear enzyme involved in the regulation of the chromatin structure and transcription…”
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TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths by Belle, Nicole Maloney, Ji, Yingbiao, Herbine, Karl, Wei, Yun, Park, JoonHyung, Zullo, Kelly, Hung, Li-Yin, Srivatsa, Sriram, Young, Tanner, Oniskey, Taylor, Pastore, Christopher, Nieves, Wildaliz, Somsouk, Ma, Herbert, De’Broski R.

“…Intestinal epithelial cells (IEC) have important functions in nutrient absorption, barrier integrity, regeneration, pathogen-sensing, and mucus secretion…”
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Poly(ADP-Ribosyl)ation of hnRNP A1 Protein Controls Translational Repression in Drosophila by Ji, Yingbiao, Tulin, Alexei V.

“…Poly(ADP-ribosyl)ation of heterogeneous nuclear ribonucleoproteins (hnRNPs) regulates the posttranscriptional fate of RNA during development. Drosophila hnRNP…”
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Post-transcriptional regulation by poly(ADP-ribosyl)ation of the RNA-binding proteins by Ji, Yingbiao, Tulin, Alexei V

“…Gene expression is intricately regulated at the post-transcriptional level by RNA-binding proteins (RBPs) via their interactions with pre-messenger RNA…”
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Poly(ADP-ribosyl)ation of heterogeneous nuclear ribonucleoproteins modulates splicing by Ji, Yingbiao, Tulin, Alexei V

“…The biological functions of poly(ADP-ribosyl)ation of heterogeneous nuclear ribonucleoproteins (hnRNPs) are not well understood. However, it is known that…”
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Poly(ADP-ribose) controls DE-cadherin-dependent stem cell maintenance and oocyte localization by Ji, Yingbiao, Tulin, Alexei V.

“…Within the short span of the cell cycle, poly(ADP-ribose) (pADPr) can be rapidly produced by poly(ADP-ribose) polymerases and degraded by poly(ADP-ribose)…”
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Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin by Kotova, Elena, Lodhi, Niraj, Jarnik, Michael, Pinnola, Aaron D, Ji, Yingbiao, Tulin, Alexei V

“…According to the histone code hypothesis, histone variants and modified histones provide binding sites for proteins that change the chromatin state to either…”
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Poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-interacting protein Hrp38 regulate pattern formation during Drosophila eye development by Ji, Yingbiao, Jarnik, Michael, Tulin, Alexei V.

“…Drosophila Hrp38, a homolog of human hnRNP A1, has been shown to regulate splicing, but its function can be modified by poly(ADP-ribosyl)ation. Notwithstanding…”
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Non-NAD-Like poly(ADP-Ribose) Polymerase-1 Inhibitors effectively Eliminate Cancer in vivo by Thomas, Colin, Ji, Yingbiao, Lodhi, Niraj, Kotova, Elena, Pinnola, Aaron Dan, Golovine, Konstantin, Makhov, Peter, Pechenkina, Kate, Kolenko, Vladimir, Tulin, Alexei V.

“…The clinical potential of PARP-1 inhibitors has been recognized >10years ago, prompting intensive research on their pharmacological application in several…”
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Approaches for Investigating Translational Regulation Controlled by PARP1: Biotin-Based UV Cross-Linking and Luciferase Reporter Assay by Ji, Yingbiao

“…The RNA-binding proteins (RBPs) play a pivotal role in controlling gene expression through posttranscriptional processes. As the trans-acting factors, RBPs…”
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Charon Mediates Immune Deficiency-Driven PARP-1-Dependent Immune Responses in Drosophila by Ji, Yingbiao, Thomas, Colin, Tulin, Nikita, Lodhi, Niraj, Boamah, Ernest, Kolenko, Vladimir, Tulin, Alexei V

“…Regulation of NF-κB nuclear translocation and stability is central to mounting an effective innate immune response. In this article, we describe a novel…”
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Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors by Anthony, Sajitha, Peterson, Jeffrey R, Ji, Yingbiao

“…Inosine monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme involved in purine nucleotide biosynthesis. It is responsible for catalyzing the…”
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Cell intrinsic Wnt4 influences cDC fate determination to suppress Type 2 immunity by Hung, Li-Yin, Johnson, John L., Ji, Yingbiao, Christian, David A., Herbine, Karl R., Pastore, Christopher F., Herbert, De’Broski R.

“…Whether conventional dendritic cells (cDC) acquire subset identity under direction of Wnt family glycoproteins is unknown. We demonstrate that Wnt4, a…”
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Wnt4 controls early cDC1 commitment to suppress Type 2 immunity by Hung, Li-Yin, Johnson, John L, Ji, Yingbiao, Christian, David A, Herbine, Karl R, Pastore, Christopher F, Herbert, De’Broski R

“…Abstract Whether conventional dendritic cells (cDC) acquire subset identity under direction of regenerative glycoproteins is unknown. We demonstrate that Wnt4,…”
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Noncovalent pADPr interaction with proteins and competition with RNA for binding to proteins by Ji, Yingbiao

“…PARP1 can modify a variety of proteins through conserved domains in noncovalent manner. Since poly(ADP-ribose) is highly negatively charged and has a strong…”
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Cell-Intrinsic Wnt4 Influences Conventional Dendritic Cell Fate Determination to Suppress Type 2 Immunity by Hung, Li-Yin, Johnson, John L, Ji, Yingbiao, Christian, David A, Herbine, Karl R, Pastore, Christopher F, Herbert, De'Broski R

“…Whether conventional dendritic cells (cDC) acquire subset identity under direction of Wnt family glycoproteins is unknown. We demonstrate that Wnt4, a…”
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Lingo3 interacts with TFF2 to control mucosal integrity, Type 1 inflammation, and colitic tissue repair by Zullo, Kelly, Ji, Yingbiao, Wei, Yun, Herbine, Karl, Maloney, Nicole, Cohen, Rachel, Pastore, Christopher, Somsouk, Ma, Srivatsa, Sriram, Hung, Li-Yin, Kohanski, Michael, Cohen, Noam, Herbert, De’Broski

“…Abstract Constant exposure of intestinal epithelial cells (IEC) to potentially damaging stimuli makes mucosal repair programs essential for gut homeostasis,…”
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LINGO3 regulates mucosal tissue regeneration and promotes TFF2 dependent recovery from colitis by Zullo, Kelly M., Douglas, Bonnie, Maloney, Nicole M., Ji, Yingbiao, Wei, Yun, Herbine, Karl, Cohen, Rachel, Pastore, Christopher, Cramer, Zvi, Wang, Xin, Wei, Wenjie, Somsouk, Ma, Hung, Li Yin, Lengner, Christopher, Kohanski, Michael H., Cohen, Noam A., Herbert, De'Broski R.

“…Aim: Recovery of damaged mucosal surfaces following inflammatory insult requires diverse regenerative mechanisms that remain poorly defined. Previously, we…”
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Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and release by Hartman, Tiffiney R, Strochlic, Todd I, Ji, Yingbiao, Zinshteyn, Daniel, O'Reilly, Alana M

“…A healthy diet improves adult stem cell function and delays diseases such as cancer, heart disease, and neurodegeneration. Defining molecular mechanisms by…”
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