Search Results - "Ji, Yelong"

Obesity exacerbates postoperative cognitive dysfunction by activating the PARP1/NAD+/SIRT1 axis through oxidative stress by Xu, Li, Ma, Yuanyuan, Ji, Yelong, Ma, Yimei, Wang, Ying, Zhao, Xining, Ge, Shengjin

“…The purposes of this study were to explore the impact of obesity on postoperative cognitive dysfunction (POCD) and to investigate the underlying mechanism by…”
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The mitochondria-targeted antioxidant MitoQ ameliorates myocardial ischemia–reperfusion injury by enhancing PINK1/Parkin-mediated mitophagy in type 2 diabetic rats by Ji, Yelong, Leng, Yan, Lei, Shaoqing, Qiu, Zhen, Ming, Hao, Zhang, Yi, Zhang, Aining, Wu, Yang, Xia, Zhongyaun

“…Type 2 diabetic hearts are more vulnerable to myocardial ischemia reperfusion (MIR) injury, which involves decreased mitophagy status with unknown mechanisms…”
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Meta-analysis of coagulation parameters associated with disease severity and poor prognosis of COVID-19 by Zhang, Aining, Leng, Yan, Zhang, Yi, Wu, Kefan, Ji, Yelong, Lei, Shaoqing, Xia, Zhongyuan

“…•COVID-19 spread rapidly around the world.•Assessed the abnormal coagulation parameters in infected patients.•Coagulopathy could be considered as a risk factor…”
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Obesity aggravated hippocampal-dependent cognitive impairment after sleeve gastrectomy in C57/BL6J mice via SIRT1/CREB/BDNF pathway by Ma, Yuanyuan, Ji, Yelong, Xu, Li, Li, Zheng, Ge, Shengjin

“…Postoperative cognitive dysfunction (POCD) is characterized by cognitive impairments following anesthesia/surgery, but the role of obesity and the underlying…”
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An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain by Ji, Yelong, Ma, Yuanyuan, Ma, Yimei, Wang, Ying, Zhao, Xining, Xu, Li, Ge, Shengjin

“…Peripheral surgery-induced neural inflammation is a key pathogenic mechanism of postoperative cognitive dysfunction (POCD). However, the mechanism underlying…”
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Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD by Ji, Yelong, Ma, Yuanyuan, Ma, Yimei, Wang, Ying, Zhao, Xining, Jin, Danfeng, Xu, Li, Ge, Shengjin

“…Neuroinflammation following peripheral surgery plays a key role in postoperative cognitive dysfunction (POCD) development and there is no effective therapy to…”
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SS-31 inhibits mtDNA–cGAS–STING signaling to improve POCD by activating mitophagy in aged mice by Ji, Yelong, Ma, Yuanyuan, Ma, Yimei, Wang, Ying, Zhao, Xining, Jin, Danfeng, Xu, Li, Ge, Shengjin

“…Background Neuroinflammation is crucial in the development of postoperative cognitive dysfunction (POCD), and microglial activation is an active participant in…”
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