Search Results - "Ji, Wangquan"
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Virology, Epidemiology, Pathogenesis, and Control of COVID-19
Published in Viruses (27-03-2020)“…The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and…”
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Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches
Published in Signal transduction and targeted therapy (24-12-2020)“…On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization. As of 4 August 2020, more than…”
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Current status of hand-foot-and-mouth disease
Published in Journal of biomedical science (24-02-2023)“…Hand-foot-and-mouth disease (HFMD) is a viral illness commonly seen in young children under 5 years of age, characterized by typical manifestations such as…”
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TBK1 and IRF3 are potential therapeutic targets in Enterovirus A71-associated diseases
Published in PLoS neglected tropical diseases (10-01-2023)“…Enterovirus A71 (EV-A71) is an important causative agent of hand-foot-and-mouth disease (HFMD) associated with enormous healthcare and socioeconomic burden…”
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Global, regional, and national burden of hearing loss in children and adolescents, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021
Published in BMC public health (16-09-2024)“…Hearing loss in children and adolescents is attracting increasing attention as a growing public health problem. This study aimed to analyze the burden of…”
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An Update on Detection Technologies for SARS-CoV-2 Variants of Concern
Published in Viruses (22-10-2022)“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is responsible for the global epidemic of Coronavirus Disease 2019 (COVID-19), with a significant…”
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Single nucleotide polymorphism of Notch1 gene rs3124599 allele is associated with the severity of CVA6-related HFMD in the Chinese Han population
Published in BMC infectious diseases (29-07-2024)“…There is evidence suggesting that Notch1 signaling pathway contributes to the development of hand, foot, and mouth disease (HFMD); however, the role of Notch1…”
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An Update on Innate Immune Responses during SARS-CoV-2 Infection
Published in Viruses (14-10-2021)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a member of the family, which is responsible for the COVID-19 pandemic followed by…”
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NLRP3 inflammasome activation contributes to acute liver injury caused by CVA6 infection in mice
Published in BMC infectious diseases (05-11-2024)“…Coxsackievirus (CV) A6 has emerged as an important causative agent in global outbreaks of hand, foot, and mouth disease (HFMD), which typically presents as a…”
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Hand, Foot, and Mouth Disease Challenges and Its Antiviral Therapeutics
Published in Vaccines (Basel) (01-03-2023)“…Hand, Foot, and Mouth Disease (HFMD) is an infectious disease caused by enteroviruses (EVs) and is extremely contagious and prevalent among infants and…”
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The Disruption of the Endothelial Barrier Contributes to Acute Lung Injury Induced by Coxsackievirus A2 Infection in Mice
Published in International journal of molecular sciences (13-09-2021)“…Sporadic occurrences and outbreaks of hand, foot, and mouth disease (HFMD) caused by Coxsackievirus A2 (CVA2) have frequently reported worldwide recently,…”
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Update on Omicron variant and its threat to vulnerable populations
Published in Public health in practice (Oxford, England) (01-06-2024)“…To reduce the incidence of severe illness and fatalities, and promote the awareness of protection and precaution, increased vaccination, strengthen the…”
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Clinical and epidemiological characteristics of 96 pediatric human metapneumovirus infections in Henan, China after COVID-19 pandemic: a retrospective analysis
Published in Virology journal (30-04-2024)“…In the aftermath of the COVID-19 pandemic, there has been a surge in human metapneumovirus (HMPV) transmission, surpassing pre-epidemic levels. We aim to…”
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Pathological Features of Enterovirus 71-Associated Brain and Lung Damage in Mice Based on Quantitative Proteomic Analysis
Published in Frontiers in microbiology (18-06-2021)“…The outbreaks of enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD) have emerged as an emergency of global health due to its association…”
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Neonatal Murine Model of Coxsackievirus A2 Infection for the Evaluation of Antiviral Therapeutics and Vaccination
Published in Frontiers in microbiology (28-05-2021)“…Coxsackievirus (CV) A2 has emerged as an important etiological agent in the pathogen spectrum of hand, foot, and mouth disease (HFMD). The symptoms of CVA2…”
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A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model
Published in Emerging microbes & infections (31-12-2022)“…CVA6 is one of Enteroviruses causing worldwide epidemics of HFMD with neurological and systemic complications. A suitable animal model is necessary for…”
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Laboratory Indicators for Identifying Hand, Foot, and Mouth Disease Severity: A Systematic Review and Meta-Analysis
Published in Vaccines (Basel) (29-10-2022)“…Objective: The purpose of this study is to study laboratory indicators for the identification of hand, foot, and mouth disease (HFMD) severity. Methods: We…”
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The key mechanisms of multi-system responses triggered by central nervous system damage in hand, foot, and mouth disease severity
Published in Infectious medicine (01-09-2024)“…•Dynamic cytokines and chemokines are related to the severity of HFMD.•Activation of the Renin-angiotensin system was implicated in the pathogenesis of…”
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The CXCL10/CXCR3 Axis Promotes Disease Pathogenesis in Mice upon CVA2 Infection
Published in Microbiology spectrum (01-06-2022)“…Coxsackievirus A2 (CVA2) is an emerging pathogen that results in hand-foot-and-mouth disease (HFMD) outbreaks. Systemic inflammatory response and central…”
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Analysis of miRNAs Involved in Mouse Heart Injury Upon Coxsackievirus A2 Infection
Published in Frontiers in cellular and infection microbiology (28-01-2022)“…Coxsackievirus A2 (CVA2) has recently been constantly detected, and is associated with viral myocarditis in children. Our previous study demonstrated that CVA2…”
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