Search Results - "Ji, Tae H."

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation by Rivero-Müller, Adolfo, Chou, Yen-Yin, Ji, Inhae, Lajic, Svetlana, Hanyaloglu, Aylin C, Jonas, Kim, Rahman, Nafis, Ji, Tae H, Huhtaniemi, Ilpo

“…G protein-coupled receptors (GPCRs) are ubiquitous mediators of signaling of hormones, neurotransmitters, and sensing. The old dogma is that a one ligand/one…”
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Two Defective Heterozygous Luteinizing Hormone Receptors Can Rescue Hormone Action by Lee, ChangWoo, Ji, Inhae, Ryu, KiSung, Song, YongSang, Conn, P. Michael, Ji, Tae H.

“…Luteinizing hormone receptor is a G protein-coupled receptor and consists of two halves: the N-terminal extracellular half (exodomain) and C-terminal…”
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Follicle-stimulating Hormone Interacts with Exoloop 3 of the Receptor by Sohn, Johann, Ryu, KiSung, Sievert, Gail, Jeoung, MyoungKun, Ji, Inhae, Ji, Tae H.

“…The human follicle-stimulating hormone (FSH) receptor consists of two distinct domains of ∼330 amino acids, the N-terminal extracellular exodomain and…”
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The Luteinizing Hormone/Chorionic Gonadotropin Receptor Has Distinct Transmembrane Conductors for cAMP and Inositol Phosphate Signals by Gilchrist, R L, Ryu, K S, Ji, I, Ji, T H

“…The luteinizing hormone/chorionic gonadotropin receptor is a member of the seven-transmembrane receptor family. It is coupled, presumably via G s and G q , to…”
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Use of defined-function mutants to access receptor–receptor interactions by Lee, ChangWoo, Ji, Inhae, Ji, Tae H

“…This article describes a novel method to access functional interactions of two defective mutant receptors. As a model, luteinizing hormone receptor, a…”
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Follicle-Stimulating Hormone Suppresses Cytosolic 3,5,3′-Triiodothyronine-Binding Protein Messenger Ribonucleic Acid Expression in Rat Granulosa Cells by Ko, CheMyong, Grieshaber, Nicole A, Ji, Inhae, Ji, Tae H

“…FSH plays crucial roles in differentiation of granulosa cells and development of follicles. Considering the broad scope of FSH effects, a large number of genes…”
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Kalirin is under-expressed in Alzheimer's disease hippocampus by Youn, HyeSook, Jeoung, MyoungKun, Koo, YongBum, Ji, Hanlee, Markesbery, William R, Ji, Inhae, Ji, Tae H

“…To identify genes aberrantly expressed in the brain of individuals with Alzheimer's Disease (AD), we analyzed RNA extracts from the hippocampus and cerebellum…”
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Cis- and Trans-Activation of Hormone Receptors: the LH Receptor by Ji, Inhae, Lee, ChangWoo, Song, YongSang, Conn, P. Michael, Ji, Tae H

“…G protein-coupled receptors (GPCRs) accommodate a wide spectrum of activators from ions to glycoprotein hormones. The mechanism of activation for this large…”
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Under-expression of Kalirin-7 Increases iNOS activity in cultured cells and correlates to elevated iNOS activity in Alzheimer's disease hippocampus by Youn, HyeSook, Ji, Inhae, Ji, Hanlee P, Markesbery, William R, Ji, Tae H

“…Recently, it has been reported that Kalirin gene transcripts are under-expressed in AD hippocampal specimens compared to the controls. The Kalirin gene…”
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Trans-activation, cis-activation and signal selection of gonadotropin receptors by Jeoung, MyoungKun, Lee, ChangWoo, Ji, Inhae, Ji, Tae H.

“…It has been thought that when a hormone binds to a receptor, the liganded receptor activates itself and generates hormone signals, such as the cAMP signal and…”
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Dominant-Negative Action of Disease-Causing Gonadotropin-Releasing Hormone Receptor (GnRHR) Mutants: A Trait That Potentially Coevolved with Decreased Plasma Membrane Expression of GnRHR in Humans by Leaños-Miranda, Alfredo, Ulloa-Aguirre, Alfredo, Ji, Tae H., Janovick, Jo Ann, Conn, P. Michael

“…Loss of function by 11 of 13 naturally occurring mutations in the human GnRH receptor (hGnRHR) was thought to result from impaired ligand binding or effector…”
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Trans-Activation of Mutant Follicle-Stimulating Hormone Receptors Selectively Generates Only One of Two Hormone Signals by Ji, Inhae, Lee, ChangWoo, Jeoung, MyoungKun, Koo, YongBum, Sievert, Gail A, Ji, Tae H

“…Previously, we reported that a liganded LH receptor (LHR) is capable of activating itself (cis-activation) and other nonliganded LHRs to induce cAMP…”
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Cis- and trans-activation of hormone receptors: the LH receptor by Ji, Inhae, Lee, ChangWoo, Song, YongSang, Conn, P Michael, Ji, Tae H

“…G protein-coupled receptors (GPCRs) accommodate a wide spectrum of activators from ions to glycoprotein hormones. The mechanism of activation for this large…”
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Cloning and Expression of a Receptor for an Insecticidal Toxin of Bacillus thuringiensis(∗) by Vadlamudi, Ratna K., Weber, Eric, Ji, Inhae, Ji, Tae H., Bulla, Lee A.

“…Environmentally friendly toxins of Bacillus thuringiensis are effective in controlling agriculturally and biomedically harmful insects. However, little is…”
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Gonadotropin-Releasing Hormone Receptor Couples to Multiple G Proteins in Rat Gonadotrophs and in GGH3 Cells: Evidence from Palmitoylation and Overexpression of G proteins by STANISLAUS, D, PONDER, S, JI, T. H, CONN, P. M

“…There is evidence in several cell systems suggesting that the GnRH receptor couples to multiple G proteins. Presently there are no published studies showing…”
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The Role of the Hinge Region of the Luteinizing Hormone Receptor in Hormone Interaction and Signal Generation by Zeng, Huawei, Phang, Tzulip, Song, Yong Sang, Ji, Inhae, Ji, Tae H.

“…Luteinizing hormone receptor, a G protein-coupled receptor, consists of two halves, the N-terminal extracellular hormone binding domain (exodomain) and the…”
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Regulation of RGS3 and RGS10 Palmitoylation by GnRH by Castro-Fernández, Cecilia, Janovick, Jo Ann, Brothers, Shaun P, Fisher, Rory A, Ji, Tae H, Conn, P. Michael

“…Regulators of G protein signaling (RGS) play a pivotal role in cellular signal transduction. RGS3 or RGS10 were overexpressed in GGH3 cells [GH3 cells stably…”
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Follicle-Stimulating Hormone-Responsive Cytoskeletal Genes in Rat Granulosa Cells: Class I β-Tubulin, Tropomyosin-4, and Kinesin Heavy Chain by Grieshaber, Nicole A, Ko, CheMyong, Grieshaber, Scott S, Ji, Inhae, Ji, Tae H

“…FSH regulates gene expression for granulosa cell differentiation and follicular development. Therefore, FSH-responsive genes are crucial, but only a few genes…”
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Orientation of follicle-stimulating hormone (FSH) subunits complexed with the FSH receptor. Beta subunit toward the N terminus of exodomain and alpha subunit to exoloop 3 by Sohn, Johann, Youn, HyeSook, Jeoung, MyoungKun, Koo, YongBum, Yi, ChongSeoung, Ji, Inhae, Ji, Tae H

“…Follicle-stimulating hormone (FSH) comprises an alpha subunit and a beta subunit, whereas the FSH receptor consists of two halves with distinct functions: the…”
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An Upstream Initiator-Like Element Suppresses Transcription of the Rat Luteinizing Hormone Receptor Gene by Youn, HyeSook, Koo, YongBum, Ji, Inhae, Ji, Tae H

“…Expression of the rat LH receptor (rLHR) is characterized by a dynamic response to a variety of hormonal stimuli. In addition to activation, the pattern of…”
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