Search Results - "Ji, Senlin"
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The Regulation and Modification of GSDMD Signaling in Diseases
Published in Frontiers in immunology (14-06-2022)“…Gasdermin D (GSDMD) serves as a key executor to trigger pyroptosis and is emerging as an attractive checkpoint in host defense, inflammatory, autoimmune…”
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Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics
Published in Biomedicine & pharmacotherapy (01-07-2024)“…Neuroimmune and neurodegenerative ailments impose a substantial societal burden. Neuroimmune disorders involve the intricate regulatory interactions between…”
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Evolutionary and genetic analysis of the VP2 gene of canine parvovirus
Published in BMC genomics (17-07-2017)“…Canine parvovirus (CPV) type 2 emerged in 1978 in the USA and quickly spread among dog populations all over the world with high morbidity. Although CPV is a…”
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Comprehensive Analysis of Codon Usage on Rabies Virus and Other Lyssaviruses
Published in International journal of molecular sciences (14-08-2018)“…Rabies virus (RABV) and other lyssaviruses can cause rabies and rabies-like diseases, which are a persistent public health threat to humans and other mammals…”
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Generation of Monoclonal Antibodies against Variable Epitopes of the M Protein of Rabies Virus
Published in Viruses (23-04-2019)“…Rabies virus (RABV), the causative agent of rabies, is highly neurovirulent for warm-blooded animals with a mortality rate of up to 100%. The RABV matrix…”
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Different Expression Profiles of Bioactive Peptides in Pelophylax nigromaculatus from Distinct Regions
Published in Bioscience, biotechnology, and biochemistry (2013)“…Amphibian skin is an abundant repository of bioactive peptides, important components of the defensive system. The variability of the bioactive peptide…”
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Molecular Cloning and Characterization of Cystatin, a Cysteine Protease Inhibitor, from Bufo melanostictus
Published in Bioscience, biotechnology, and biochemistry (2013)“…Cystatins are efficient inhibitors of papain-like cysteine proteinases, and they serve various important physiological functions. In this study, a novel…”
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One Health strategies for rabies control in rural areas of China
Published in The Lancet infectious diseases (01-04-2017)“…In December, 2015, WHO proposed to eradicate rabies transmission from dogs to human beings by 2030 as described in a Comment by Dara Mohammadi.1 At present,…”
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Identification of D359-0396 as a novel inhibitor of the activation of NLRP3 inflammasome
Published in Neurochemistry international (01-10-2023)“…Pyroptosis is a unique pro-inflammatory form of programmed cell death which plays a critical role in promoting the pathogenesis of multiple inflammatory and…”
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The co-chaperone Cdc37 regulates the rabies virus phosphoprotein stability by targeting to Hsp90AA1 machinery
Published in Scientific reports (02-06-2016)“…Cdc37, as a kinase-specific co-chaperone of the chaperone Hsp90AA1 (Hsp90), actively aids with the maturation, stabilization and activation of the cellular or…”
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Identification of a Small Molecule with Strong Anti-Inflammatory Activity in Experimental Autoimmune Encephalomyelitis and Sepsis through Blocking Gasdermin D Activation
Published in The Journal of immunology (1950) (15-08-2022)“…Abstract Pyroptosis is a key inflammatory form of cell death participating in the progression of many inflammatory diseases, such as experimental autoimmune…”
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Microarray analysis of lncRNA expression in rabies virus infected human neuroblastoma cells
Published in Infection, genetics and evolution (01-01-2019)“…Rabies, caused by the rabies virus (RABV), is the oldest known zoonotic infectious disease. Although the molecular mechanisms of RABV pathogenesis have been…”
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Characterization of H7N2 Avian Influenza Virus in Wild Birds and Pikas in Qinghai-Tibet Plateau Area
Published in Scientific reports (24-08-2016)“…Qinghai Lake is a major migrating bird breeding site that has experienced several recent highly pathogenic avian influenza virus (HPAIV) epizootics. From 2006…”
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