Search Results - "Ji, Dongmei"

Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma by Pu, Weilin, Shi, Xiao, Yu, Pengcheng, Zhang, Meiying, Liu, Zhiyan, Tan, Licheng, Han, Peizhen, Wang, Yu, Ji, Dongmei, Gan, Hualei, Wei, Wenjun, Lu, Zhongwu, Qu, Ning, Hu, Jiaqian, Hu, Xiaohua, Luo, Zaili, Li, Huajun, Ji, Qinghai, Wang, Jiucun, Zhang, Xiaoming, Wang, Yu-Long

“…The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using single-cell RNA sequencing, we profile transcriptomes of 158,577 cells…”
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Apatinib for Chemotherapy-Refractory Advanced Metastatic Gastric Cancer: Results From a Randomized, Placebo-Controlled, Parallel-Arm, Phase II Trial by Li, Jin, Qin, Shukui, Xu, Jianming, Guo, Weijian, Xiong, Jianping, Bai, Yuxian, Sun, Guoping, Yang, Yan, Wang, Liwei, Xu, Nong, Cheng, Ying, Wang, Zhehai, Zheng, Leizhen, Tao, Min, Zhu, Xiaodong, Ji, Dongmei, Liu, Xin, Yu, Hao

“…Patients with metastatic gastric cancer (mGC) who do not respond to or who experience progression with second-line chemotherapy have no treatment options that…”
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Correction of a pathogenic gene mutation in human embryos by Ma, Hong, Marti-Gutierrez, Nuria, Park, Sang-Wook, Wu, Jun, Lee, Yeonmi, Suzuki, Keiichiro, Koski, Amy, Ji, Dongmei, Hayama, Tomonari, Ahmed, Riffat, Darby, Hayley, Van Dyken, Crystal, Li, Ying, Kang, Eunju, Park, A.-Reum, Kim, Daesik, Kim, Sang-Tae, Gong, Jianhui, Gu, Ying, Xu, Xun, Battaglia, David, Krieg, Sacha A., Lee, David M., Wu, Diana H., Wolf, Don P., Heitner, Stephen B., Belmonte, Juan Carlos Izpisua, Amato, Paula, Kim, Jin-Soo, Kaul, Sanjiv, Mitalipov, Shoukhrat

“…Genome editing has potential for the targeted correction of germline mutations. Here we describe the correction of the heterozygous MYBPC3 mutation in human…”
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Polar Body Genome Transfer for Preventing the Transmission of Inherited Mitochondrial Diseases by Wang, Tian, Sha, Hongying, Ji, Dongmei, Zhang, Helen L., Chen, Dawei, Cao, Yunxia, Zhu, Jianhong

“…Inherited mtDNA diseases transmit maternally and cause severe phenotypes. Currently, there is no effective therapy or genetic screens for these diseases;…”
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Bayesian Network Structure Learning Algorithm Combining Improved Dragonfly optimization by Ji, Dongmei, Sun, Zheng

“…Bayesian network structure learning is one of the current research hotspots in fields such as statistics and machine learning. Although it has great potential…”
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High accumulation of Mx2 renders limited multiplication of oncolytic herpes simplex virus-1 in human tumor cells by Ren, Yong, Chen, Meiling, Wu, Guangxian, Ji, Dongmei, Zhou, Grace Guoying, Ren, Pei-Gen, Fu, Wenmin

“…Increasing studies demonstrated that oncolytic activities of oHSV-1 are limited to the capacity of virus replicating in tumors. In order to potentiate the…”
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First-in-human phase I dose-escalation and dose-expansion trial of the selective MEK inhibitor HL-085 in patients with advanced melanoma harboring NRAS mutations by Wang, Xuan, Luo, Zhiguo, Chen, Jing, Chen, Yu, Ji, Dongmei, Fan, Li, Chen, Ling, Zhao, Qian, Hu, Pei, Sun, Peng, Jia, Zhongwei, Guo, Jun, Si, Lu

“…HL-085 is a selective, orally administered MEK1/2 inhibitor. We aimed to evaluate the safety and efficacy of HL-085 in patients with advanced melanoma…”
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The associations of the concentrations of toxic metals (including metalloid) in blood and follicular fluid with the risk of diminished ovarian reserve by Yue, Xinyu, Li, Qian, Tao, Jiajing, Zhang, Hua, Peng, Jie, Zhang, Dongyang, Yang, Jing, Ji, Duoxu, Tao, Fangbiao, Cao, Yunxia, Ji, Dongmei, Liang, Chunmei

“…Diminished ovarian reserve (DOR), a triggering factor for female infertility, affects 10% ∼ 35% of women of reproductive age. It is still unclear whether…”
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The associations of serum metals concentrations with the intermediate and pregnancy outcomes in women undergoing in vitro fertilization (IVF) by Li, Danyang, Liang, Chunmei, Cao, Yu, Zhu, Damin, Shen, Lingchao, Zhang, Zhikang, Jiang, Tingting, Zhang, Zhou, Zong, Kai, Liu, Yajing, Liang, Dan, Cao, Yunxia, Ji, Dongmei, Xu, Xiaofeng

“…Toxic and essential trace elements are reported to have impact on female fertility. However, studies on the potential synergistic or antagonistic effects of…”
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Elevated levels of Zn, Cu and Co are associated with an increased risk of endometriosis: Results from a case control study by Su, Xun, Yue, Xinyu, Zhang, Ying, Shen, Lingchao, Zhang, Huan, Wang, Xin, Yin, Tao, Zhang, Hua, Peng, Jie, Wang, Xiaolei, Zou, Weiwei, Liang, Dan, Du, Yinan, Liu, Yajing, Cao, Yunxia, Ji, Dongmei, Liang, Chunmei

“…Background: Endometriosis is a common gynecological disease that affects approximately 5 %∼10 % of reproductive-aged women. Zinc (Zn), selenium (Se), copper…”
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Functional Genetic Approach Identifies MET, HER3, IGF1R, INSR Pathways as Determinants of Lapatinib Unresponsiveness in HER2-Positive Gastric Cancer by Zhang, Zhe, Wang, Jiping, Ji, Dongmei, Wang, Chenchen, Liu, Rujiao, Wu, Zheng, Liu, Lian, Zhu, Dan, Chang, Jinjia, Geng, Ruixuan, Xiong, Lei, Fang, Qiangyi, Li, Jin

“…Targeting human epidermal growth factor receptor 2 (HER2) therapy is currently considered as the standard treatment for HER2-positive (HER2+) advanced gastric…”
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Targeting of focal adhesion kinase enhances the immunogenic cell death of PEGylated liposome doxorubicin to optimize therapeutic responses of immune checkpoint blockade by Zhang, Baoyuan, Li, Ning, Gao, Jiaming, Zhao, Yuxi, Jiang, Jun, Xie, Shuang, Zhang, Cuiping, Zhang, Qingyu, Liu, Leo, Wang, Zaiqi, Ji, Dongmei, Wu, Lingying, Ren, Ruibao

“…Immune checkpoint blockade (ICB) is widely considered to exert long-term treatment benefits by activating antitumor immunity. However, many cancer patients…”
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Pathogenic mitochondrial DNA 3243A>G mutation: From genetics to phenotype by Li, Danyang, Liang, Chunmei, Zhang, Tao, Marley, Jordan Lee, Zou, Weiwei, Lian, Muqing, Ji, Dongmei

“…The mitochondrial DNA (mtDNA) m.3243A>G mutation is one of the most common pathogenic mtDNA variants, showing complex genetics, pathogenic molecular…”
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Activity and safety of SHR3680, a novel antiandrogen, in patients with metastatic castration-resistant prostate cancer: a phase I/II trial by Qin, Xiaojian, Ji, Dongmei, Gu, Weijie, Han, Weiqing, Luo, Hong, Du, Chuanjun, Zou, Qing, Sun, Zhongquan, He, Chaohong, Zhu, Shaoxing, Chong, Tie, Yao, Xin, Wan, Ben, Yang, Xinfeng, Bai, Aobing, Jin, Chunlei, Zou, Jianjun, Ye, Dingwei

“…Antagonizing the androgen-receptor (AR) pathway is an effective treatment strategy for patients with metastatic castration-resistant prostate cancer (CRPC)…”
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Cervical balloon combined with oxytocin improves clinical efficacy and safety for induction of labor with scarred uterus by Ji, Dongmei, Ding, Juhua, Li, Xiaoqiong, Li, Gang, Yin, Dong

“…Background: To evaluate cervical balloon combined with oxytocin improves clinical efficacy and safety for induction of labor with scarred uterus. Methods: The…”
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Correction: Targeting of focal adhesion kinase enhances the immunogenic cell death of PEGylated liposome doxorubicin to optimize therapeutic responses of immune checkpoint blockade by Zhang, Baoyuan, Li, Ning, Gao, Jiaming, Zhao, Yuxi, Jiang, Jun, Xie, Shuang, Zhang, Cuiping, Zhang, Qingyu, Liu, Leo, Wang, Zaiqi, Ji, Dongmei, Wu, Lingying, Ren, Ruibao

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Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models by Wu, Yinglin, Chen, Xiaoqing, Wang, Lei, Zhou, Xusha, Liu, Yonghong, Ji, Dongmei, Ren, Peigen, Zhou, Grace Guoying, Zhao, Jing

“…Combination therapy has been widely explored for oncolytic virus (OV), as it can be met with tumor resistance. The HDAC inhibitor (HDACi) panobinostat is a…”
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Influence of combined exposure levels of total arsenic and inorganic arsenic on arsenic methylation capacity among university students: findings from Bayesian kernel machine regression analysis by Jiang, Rui, Zhang, Qing, Ji, Dongmei, Jiang, Tingting, Hu, Yuan, He, Shitao, Tao, Long, Shen, Juan, Zhang, Wei, Song, Yuxiang, Ma, Yicheng, Tong, Shilu, Tao, Fangbiao, Yao, Yuyou, Liang, Chunmei

“…The arsenic (As) methylation capacity is an important determinant of susceptibility to As-related diseases. Total As (TAs) or inorganic As (iAs) was reported…”
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Four cycles of R-CHOP followed by two applications of rituximab based on negative interim PET/CT: an analysis of a prospective trial by Jin, Jia, Ji, Dongmei, Xia, Zuguang, Xue, Kai, Zhang, Qunling, Liu, Yizhen, Cao, Junning, Hong, Xiaonan, Gu, Juan J, Guo, Ye, Lv, Fangfang

“…R-CHOP with or without radiotherapy is the standard treatment for limited-stage diffuse large B-cell lymphoma (DLBCL). To prevent overtreatment, we assessed…”
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Players in Mitochondrial Dynamics and Female Reproduction by Zou, Weiwei, Ji, Dongmei, Zhang, Zhiguo, Yang, Li, Cao, Yunxia

“…Mitochondrial dynamics (fission and fusion) are essential physiological processes for mitochondrial metabolic function, mitochondrial redistribution, and…”
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